Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367610010> ?p ?o ?g. }
- W4367610010 endingPage "1567" @default.
- W4367610010 startingPage "1555" @default.
- W4367610010 abstract "Older adults with Type II Diabetes Mellitus (DM) experience mild cognitive impairment, specifically in the domain of recall/working memory. No consistent causative structural cortical deficits have been identified in persons with DM (PwDM). Memory deficits may be exacerbated in older adult females, who are at the highest risk of cardiovascular decline due to DM. The focus of the current study was to evaluate functional cortical hemodynamic activity during memory tasks in postmenopausal PwDM. Functional Near Infrared Spectroscopy (fNIRS) was used to monitor oxyhemoglobin (HbO) and deoxyhemoglobin (HbR) during memory-based tasks in a cross-sectional sample of postmenopausal women with DM. Twenty-one community-dwelling DM females (age = 65 ± 6 years) and twenty-one age- and sex-matched healthy controls (age = 66 ± 6 years) were evaluated. Working memory performance (via N-back) was evaluated while study participants donned cortical fNIRS. Health state, metabolic data, and menopausal status data were also collected. Deficits in working memory accuracy were found in the DM group as compared to controls. Differences in HbO responses emerged in the DM group. The DM group exhibited altered PFC activity magnitudes and increased functional cortical activity across ROIs compared to controls. HbO and HbR responses were not associated with worsened health state measures. These data indicate a shift in cortical activity patterns with memory deficits in postmenopausal PwDM. This DM-specific shift of HbO is a novel finding that is unlikely to be detected by fMRI. This underscores the value of using non-MRI-based neuroimaging techniques to evaluate cortical hemodynamic function to detect early mild cognitive impairment." @default.
- W4367610010 created "2023-05-02" @default.
- W4367610010 creator A5003875383 @default.
- W4367610010 creator A5004437210 @default.
- W4367610010 creator A5011211745 @default.
- W4367610010 creator A5030442054 @default.
- W4367610010 creator A5034398320 @default.
- W4367610010 creator A5034923948 @default.
- W4367610010 creator A5038527573 @default.
- W4367610010 creator A5042785173 @default.
- W4367610010 creator A5081775625 @default.
- W4367610010 date "2023-05-01" @default.
- W4367610010 modified "2023-09-27" @default.
- W4367610010 title "Functional near infrared spectroscopy detects cortical activation changes concurrent with memory loss in postmenopausal women with Type II Diabetes" @default.
- W4367610010 cites W1532021133 @default.
- W4367610010 cites W1906317191 @default.
- W4367610010 cites W1908953877 @default.
- W4367610010 cites W1909861402 @default.
- W4367610010 cites W1965801493 @default.
- W4367610010 cites W1966759687 @default.
- W4367610010 cites W1968000777 @default.
- W4367610010 cites W1968474912 @default.
- W4367610010 cites W1968703316 @default.
- W4367610010 cites W1973003238 @default.
- W4367610010 cites W1985304419 @default.
- W4367610010 cites W1991550546 @default.
- W4367610010 cites W1992529560 @default.
- W4367610010 cites W1997130084 @default.
- W4367610010 cites W1997935250 @default.
- W4367610010 cites W1999124715 @default.
- W4367610010 cites W2009792683 @default.
- W4367610010 cites W2022774148 @default.
- W4367610010 cites W2026283383 @default.
- W4367610010 cites W2046254753 @default.
- W4367610010 cites W2081898812 @default.
- W4367610010 cites W2087732718 @default.
- W4367610010 cites W2097880694 @default.
- W4367610010 cites W2105957367 @default.
- W4367610010 cites W2122600842 @default.
- W4367610010 cites W2124625759 @default.
- W4367610010 cites W2125956101 @default.
- W4367610010 cites W2136022845 @default.
- W4367610010 cites W2136800398 @default.
- W4367610010 cites W2137523819 @default.
- W4367610010 cites W2139133769 @default.
- W4367610010 cites W2141505663 @default.
- W4367610010 cites W2156177387 @default.
- W4367610010 cites W2157526886 @default.
- W4367610010 cites W2157957223 @default.
- W4367610010 cites W2165758561 @default.
- W4367610010 cites W2318272148 @default.
- W4367610010 cites W2345328813 @default.
- W4367610010 cites W2404801683 @default.
- W4367610010 cites W2405118675 @default.
- W4367610010 cites W2473051925 @default.
- W4367610010 cites W2549242739 @default.
- W4367610010 cites W2568954607 @default.
- W4367610010 cites W2583224357 @default.
- W4367610010 cites W2586484764 @default.
- W4367610010 cites W2733572936 @default.
- W4367610010 cites W2803554436 @default.
- W4367610010 cites W2885026379 @default.
- W4367610010 cites W2886301707 @default.
- W4367610010 cites W2889170055 @default.
- W4367610010 cites W2896400195 @default.
- W4367610010 cites W2912841818 @default.
- W4367610010 cites W2963123582 @default.
- W4367610010 cites W2973738822 @default.
- W4367610010 cites W2982402476 @default.
- W4367610010 cites W3004625228 @default.
- W4367610010 cites W3017190883 @default.
- W4367610010 cites W3020298514 @default.
- W4367610010 cites W3082399512 @default.
- W4367610010 cites W3087884588 @default.
- W4367610010 cites W3140082799 @default.
- W4367610010 cites W3180268861 @default.
- W4367610010 cites W3184637193 @default.
- W4367610010 cites W4225009033 @default.
- W4367610010 cites W4282969561 @default.
- W4367610010 doi "https://doi.org/10.1007/s00221-023-06581-1" @default.
- W4367610010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37127798" @default.
- W4367610010 hasPublicationYear "2023" @default.
- W4367610010 type Work @default.
- W4367610010 citedByCount "1" @default.
- W4367610010 countsByYear W43676100102023 @default.
- W4367610010 crossrefType "journal-article" @default.
- W4367610010 hasAuthorship W4367610010A5003875383 @default.
- W4367610010 hasAuthorship W4367610010A5004437210 @default.
- W4367610010 hasAuthorship W4367610010A5011211745 @default.
- W4367610010 hasAuthorship W4367610010A5030442054 @default.
- W4367610010 hasAuthorship W4367610010A5034398320 @default.
- W4367610010 hasAuthorship W4367610010A5034923948 @default.
- W4367610010 hasAuthorship W4367610010A5038527573 @default.
- W4367610010 hasAuthorship W4367610010A5042785173 @default.
- W4367610010 hasAuthorship W4367610010A5081775625 @default.
- W4367610010 hasBestOaLocation W43676100102 @default.
- W4367610010 hasConcept C100660578 @default.
- W4367610010 hasConcept C126322002 @default.