Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367623873> ?p ?o ?g. }
- W4367623873 endingPage "721" @default.
- W4367623873 startingPage "714" @default.
- W4367623873 abstract "Molecules that contain a stereogenic phosphorus atom are crucial to medicine, agrochemistry and catalysis. While methods are available for the selective construction of various chiral organophosphorus compounds, catalytic enantioselective approaches for their synthesis are far less common. Given the vastness of possible substituent combinations around a phosphorus atom, protocols for their preparation should also be divergent, providing facile access not only to one but to many classes of phosphorus compounds. Here we introduce a catalytic and enantioselective strategy for the preparation of an enantioenriched phosphorus(V) centre that can be diversified enantiospecifically to a wide range of biologically relevant phosphorus(V) compounds. The process, which involves an enantioselective nucleophilic substitution catalysed by a superbasic bifunctional iminophosphorane catalyst, can accommodate a wide range of carbon substituents at phosphorus. The resulting stable, yet versatile, synthetic intermediates can be combined with a multitude of medicinally relevant O-, N- and S-based nucleophiles." @default.
- W4367623873 created "2023-05-02" @default.
- W4367623873 creator A5007839860 @default.
- W4367623873 creator A5008000365 @default.
- W4367623873 creator A5013010105 @default.
- W4367623873 creator A5013585464 @default.
- W4367623873 creator A5013804286 @default.
- W4367623873 creator A5058975914 @default.
- W4367623873 creator A5059540181 @default.
- W4367623873 creator A5078075979 @default.
- W4367623873 creator A5080148464 @default.
- W4367623873 creator A5080707337 @default.
- W4367623873 date "2023-05-01" @default.
- W4367623873 modified "2023-09-30" @default.
- W4367623873 title "Catalytic enantioselective nucleophilic desymmetrization of phosphonate esters" @default.
- W4367623873 cites W1975688146 @default.
- W4367623873 cites W2017708936 @default.
- W4367623873 cites W2022176339 @default.
- W4367623873 cites W2027414936 @default.
- W4367623873 cites W2053083338 @default.
- W4367623873 cites W2063253214 @default.
- W4367623873 cites W2091119032 @default.
- W4367623873 cites W2091461549 @default.
- W4367623873 cites W2132656062 @default.
- W4367623873 cites W2142218301 @default.
- W4367623873 cites W2150973112 @default.
- W4367623873 cites W2170656464 @default.
- W4367623873 cites W2225637732 @default.
- W4367623873 cites W2292021561 @default.
- W4367623873 cites W2318555877 @default.
- W4367623873 cites W2324777773 @default.
- W4367623873 cites W2333320944 @default.
- W4367623873 cites W2409572969 @default.
- W4367623873 cites W2464309602 @default.
- W4367623873 cites W2493630713 @default.
- W4367623873 cites W2527149090 @default.
- W4367623873 cites W2607504039 @default.
- W4367623873 cites W2608862652 @default.
- W4367623873 cites W2742581645 @default.
- W4367623873 cites W2768088417 @default.
- W4367623873 cites W2802454936 @default.
- W4367623873 cites W2886572205 @default.
- W4367623873 cites W2899249903 @default.
- W4367623873 cites W2920844349 @default.
- W4367623873 cites W2941122258 @default.
- W4367623873 cites W2969524563 @default.
- W4367623873 cites W2970784242 @default.
- W4367623873 cites W2979128015 @default.
- W4367623873 cites W2989475738 @default.
- W4367623873 cites W2991620646 @default.
- W4367623873 cites W3008653361 @default.
- W4367623873 cites W3011384835 @default.
- W4367623873 cites W3012372987 @default.
- W4367623873 cites W3014457157 @default.
- W4367623873 cites W3022799436 @default.
- W4367623873 cites W3030203986 @default.
- W4367623873 cites W3039747299 @default.
- W4367623873 cites W3083688366 @default.
- W4367623873 cites W3155177878 @default.
- W4367623873 cites W3163343020 @default.
- W4367623873 cites W4200561672 @default.
- W4367623873 cites W4236119433 @default.
- W4367623873 cites W4282917882 @default.
- W4367623873 doi "https://doi.org/10.1038/s41557-023-01165-6" @default.
- W4367623873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37127757" @default.
- W4367623873 hasPublicationYear "2023" @default.
- W4367623873 type Work @default.
- W4367623873 citedByCount "6" @default.
- W4367623873 countsByYear W43676238732023 @default.
- W4367623873 crossrefType "journal-article" @default.
- W4367623873 hasAuthorship W4367623873A5007839860 @default.
- W4367623873 hasAuthorship W4367623873A5008000365 @default.
- W4367623873 hasAuthorship W4367623873A5013010105 @default.
- W4367623873 hasAuthorship W4367623873A5013585464 @default.
- W4367623873 hasAuthorship W4367623873A5013804286 @default.
- W4367623873 hasAuthorship W4367623873A5058975914 @default.
- W4367623873 hasAuthorship W4367623873A5059540181 @default.
- W4367623873 hasAuthorship W4367623873A5078075979 @default.
- W4367623873 hasAuthorship W4367623873A5080148464 @default.
- W4367623873 hasAuthorship W4367623873A5080707337 @default.
- W4367623873 hasBestOaLocation W43676238731 @default.
- W4367623873 hasConcept C134195300 @default.
- W4367623873 hasConcept C146686406 @default.
- W4367623873 hasConcept C161790260 @default.
- W4367623873 hasConcept C178790620 @default.
- W4367623873 hasConcept C178907741 @default.
- W4367623873 hasConcept C185592680 @default.
- W4367623873 hasConcept C21951064 @default.
- W4367623873 hasConcept C2777190055 @default.
- W4367623873 hasConcept C2777626080 @default.
- W4367623873 hasConcept C2778689049 @default.
- W4367623873 hasConcept C2780443040 @default.
- W4367623873 hasConceptScore W4367623873C134195300 @default.
- W4367623873 hasConceptScore W4367623873C146686406 @default.
- W4367623873 hasConceptScore W4367623873C161790260 @default.
- W4367623873 hasConceptScore W4367623873C178790620 @default.
- W4367623873 hasConceptScore W4367623873C178907741 @default.
- W4367623873 hasConceptScore W4367623873C185592680 @default.