Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367627890> ?p ?o ?g. }
- W4367627890 endingPage "819" @default.
- W4367627890 startingPage "819" @default.
- W4367627890 abstract "The enzymatic acetylation in the organic solvents of a number of the important bioactive cardiac glycosides was investigated. With the bufanolide proscillaridin A and the cardenolide lanatoside C, acylation, as expected, occurred at the secondary 4′-OH of the rhamnopyranosyl unit of the former (by the action of Novozym 435 lipase) and the primary 6′′′′-OH of the terminal glucopyranosyl unit of the latter (best results obtained by the action of the lipase PS). Only lipase PS was found to be able to acylate the cardenolides digitoxin and digoxin at the 4‴-OH of their terminal digitoxose unit. The corresponding monoacetyl derivatives, both of which are commercialized drugs, could be isolated with good yields. The investigation of the Novozym 435-catalyzed acetylation of free D-digitoxose provided a possible explanation for the inability of this lipase to acylate digitoxin and digoxin." @default.
- W4367627890 created "2023-05-02" @default.
- W4367627890 creator A5048507060 @default.
- W4367627890 creator A5059538213 @default.
- W4367627890 creator A5065889825 @default.
- W4367627890 creator A5080608218 @default.
- W4367627890 date "2023-04-28" @default.
- W4367627890 modified "2023-09-26" @default.
- W4367627890 title "Regioselective Esterification of Cardiac Glycosides Catalyzed by Novozym 435 and Lipase PS in Organic Solvents" @default.
- W4367627890 cites W1563892911 @default.
- W4367627890 cites W1968081336 @default.
- W4367627890 cites W1975924867 @default.
- W4367627890 cites W1988461682 @default.
- W4367627890 cites W1991587605 @default.
- W4367627890 cites W2002298824 @default.
- W4367627890 cites W2006350653 @default.
- W4367627890 cites W2011143887 @default.
- W4367627890 cites W2014676992 @default.
- W4367627890 cites W2019253270 @default.
- W4367627890 cites W2025769792 @default.
- W4367627890 cites W2033046219 @default.
- W4367627890 cites W2040286050 @default.
- W4367627890 cites W2050754435 @default.
- W4367627890 cites W2053955693 @default.
- W4367627890 cites W2055297061 @default.
- W4367627890 cites W2059572160 @default.
- W4367627890 cites W2070225898 @default.
- W4367627890 cites W2076666035 @default.
- W4367627890 cites W2077757044 @default.
- W4367627890 cites W2085581766 @default.
- W4367627890 cites W2090135106 @default.
- W4367627890 cites W2092815460 @default.
- W4367627890 cites W2139194456 @default.
- W4367627890 cites W2215177355 @default.
- W4367627890 cites W2279474689 @default.
- W4367627890 cites W2542750231 @default.
- W4367627890 cites W2604567954 @default.
- W4367627890 cites W2624370041 @default.
- W4367627890 cites W2767707410 @default.
- W4367627890 cites W2808680713 @default.
- W4367627890 cites W2940571490 @default.
- W4367627890 cites W2953145956 @default.
- W4367627890 cites W3003151291 @default.
- W4367627890 cites W3157759727 @default.
- W4367627890 cites W3168441456 @default.
- W4367627890 cites W3193543560 @default.
- W4367627890 cites W3212432902 @default.
- W4367627890 cites W4281705023 @default.
- W4367627890 cites W4281847138 @default.
- W4367627890 cites W2073339621 @default.
- W4367627890 doi "https://doi.org/10.3390/catal13050819" @default.
- W4367627890 hasPublicationYear "2023" @default.
- W4367627890 type Work @default.
- W4367627890 citedByCount "0" @default.
- W4367627890 crossrefType "journal-article" @default.
- W4367627890 hasAuthorship W4367627890A5048507060 @default.
- W4367627890 hasAuthorship W4367627890A5059538213 @default.
- W4367627890 hasAuthorship W4367627890A5065889825 @default.
- W4367627890 hasAuthorship W4367627890A5080608218 @default.
- W4367627890 hasBestOaLocation W43676278901 @default.
- W4367627890 hasConcept C104317684 @default.
- W4367627890 hasConcept C119157956 @default.
- W4367627890 hasConcept C126322002 @default.
- W4367627890 hasConcept C161790260 @default.
- W4367627890 hasConcept C178790620 @default.
- W4367627890 hasConcept C181199279 @default.
- W4367627890 hasConcept C185592680 @default.
- W4367627890 hasConcept C193557335 @default.
- W4367627890 hasConcept C194671627 @default.
- W4367627890 hasConcept C2777707475 @default.
- W4367627890 hasConcept C2777781521 @default.
- W4367627890 hasConcept C2778198053 @default.
- W4367627890 hasConcept C2779542420 @default.
- W4367627890 hasConcept C2779697368 @default.
- W4367627890 hasConcept C2780628665 @default.
- W4367627890 hasConcept C55493867 @default.
- W4367627890 hasConcept C71924100 @default.
- W4367627890 hasConceptScore W4367627890C104317684 @default.
- W4367627890 hasConceptScore W4367627890C119157956 @default.
- W4367627890 hasConceptScore W4367627890C126322002 @default.
- W4367627890 hasConceptScore W4367627890C161790260 @default.
- W4367627890 hasConceptScore W4367627890C178790620 @default.
- W4367627890 hasConceptScore W4367627890C181199279 @default.
- W4367627890 hasConceptScore W4367627890C185592680 @default.
- W4367627890 hasConceptScore W4367627890C193557335 @default.
- W4367627890 hasConceptScore W4367627890C194671627 @default.
- W4367627890 hasConceptScore W4367627890C2777707475 @default.
- W4367627890 hasConceptScore W4367627890C2777781521 @default.
- W4367627890 hasConceptScore W4367627890C2778198053 @default.
- W4367627890 hasConceptScore W4367627890C2779542420 @default.
- W4367627890 hasConceptScore W4367627890C2779697368 @default.
- W4367627890 hasConceptScore W4367627890C2780628665 @default.
- W4367627890 hasConceptScore W4367627890C55493867 @default.
- W4367627890 hasConceptScore W4367627890C71924100 @default.
- W4367627890 hasIssue "5" @default.
- W4367627890 hasLocation W43676278901 @default.
- W4367627890 hasLocation W43676278902 @default.
- W4367627890 hasOpenAccess W4367627890 @default.