FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367665613> ?p ?o ?g. }

• W4367665613 abstract "Ssu72, a dual-specificity protein phosphatase, not only participates in transcription biogenesis, but also affects pathophysiological functions in a tissue-specific manner. Recently, it has been shown that Ssu72 is required for T cell differentiation and function by controlling multiple immune receptor-mediated signals, including TCR and several cytokine receptor signaling pathways. Ssu72 deficiency in T cells is associated with impaired fine-tuning of receptor-mediated signaling and a defect in CD4+ T cell homeostasis, resulting in immune-mediated diseases. However, the mechanism by which Ssu72 in T cells integrates the pathophysiology of multiple immune-mediated diseases is still poorly elucidated. In this review, we will focus on the immunoregulatory mechanism of Ssu72 phosphatase in CD4+ T cell differentiation, activation, and phenotypic function. We will also discuss the current understanding of the correlation between Ssu72 in T cells and pathological functions which suggests that Ssu72 might be a therapeutic target in autoimmune disorders and other diseases." @default.
• W4367665613 created "2023-05-03" @default.
• W4367665613 creator A5056337221 @default.
• W4367665613 creator A5057812772 @default.
• W4367665613 date "2023-01-01" @default.
• W4367665613 modified "2023-10-15" @default.
• W4367665613 title "Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages" @default.
• W4367665613 cites W1516387210 @default.
• W4367665613 cites W1537063289 @default.
• W4367665613 cites W1596258860 @default.
• W4367665613 cites W1777296950 @default.
• W4367665613 cites W1913298513 @default.
• W4367665613 cites W1958742527 @default.
• W4367665613 cites W1968913955 @default.
• W4367665613 cites W1973454407 @default.
• W4367665613 cites W1982496217 @default.
• W4367665613 cites W1982926364 @default.
• W4367665613 cites W1993712998 @default.
• W4367665613 cites W1995957006 @default.
• W4367665613 cites W2001941062 @default.
• W4367665613 cites W2008512592 @default.
• W4367665613 cites W2009644403 @default.
• W4367665613 cites W2010519878 @default.
• W4367665613 cites W2011446655 @default.
• W4367665613 cites W2014489332 @default.
• W4367665613 cites W2016827757 @default.
• W4367665613 cites W2020304403 @default.
• W4367665613 cites W2024727248 @default.
• W4367665613 cites W2025761406 @default.
• W4367665613 cites W2026111998 @default.
• W4367665613 cites W2027699993 @default.
• W4367665613 cites W2029640857 @default.
• W4367665613 cites W2032547672 @default.
• W4367665613 cites W2043776488 @default.
• W4367665613 cites W2047566174 @default.
• W4367665613 cites W2052998574 @default.
• W4367665613 cites W2056097637 @default.
• W4367665613 cites W2071131149 @default.
• W4367665613 cites W2073672027 @default.
• W4367665613 cites W2074438676 @default.
• W4367665613 cites W2076799533 @default.
• W4367665613 cites W2088233979 @default.
• W4367665613 cites W2091945743 @default.
• W4367665613 cites W2092894985 @default.
• W4367665613 cites W2095164057 @default.
• W4367665613 cites W2097811455 @default.
• W4367665613 cites W2100699905 @default.
• W4367665613 cites W2103600875 @default.
• W4367665613 cites W2104401957 @default.
• W4367665613 cites W2108259296 @default.
• W4367665613 cites W2111048478 @default.
• W4367665613 cites W2119236548 @default.
• W4367665613 cites W2119649463 @default.
• W4367665613 cites W2121219094 @default.
• W4367665613 cites W2121227637 @default.
• W4367665613 cites W2126060249 @default.
• W4367665613 cites W2126874760 @default.
• W4367665613 cites W2127809081 @default.
• W4367665613 cites W2131486699 @default.
• W4367665613 cites W2131678280 @default.
• W4367665613 cites W2132216539 @default.
• W4367665613 cites W2138609584 @default.
• W4367665613 cites W2141649011 @default.
• W4367665613 cites W2142017607 @default.
• W4367665613 cites W2146607274 @default.
• W4367665613 cites W2148712172 @default.
• W4367665613 cites W2150505180 @default.
• W4367665613 cites W2155779547 @default.
• W4367665613 cites W2160241168 @default.
• W4367665613 cites W2166282414 @default.
• W4367665613 cites W2166356293 @default.
• W4367665613 cites W2211069246 @default.
• W4367665613 cites W2284327277 @default.
• W4367665613 cites W2337534061 @default.
• W4367665613 cites W2507334943 @default.
• W4367665613 cites W2576351276 @default.
• W4367665613 cites W2600881183 @default.
• W4367665613 cites W2601742683 @default.
• W4367665613 cites W2612220899 @default.
• W4367665613 cites W2623733076 @default.
• W4367665613 cites W2734775771 @default.
• W4367665613 cites W2740495409 @default.
• W4367665613 cites W2777469091 @default.
• W4367665613 cites W2786987313 @default.
• W4367665613 cites W2791371888 @default.
• W4367665613 cites W2793633504 @default.
• W4367665613 cites W2797429263 @default.
• W4367665613 cites W2803300773 @default.
• W4367665613 cites W2889022810 @default.
• W4367665613 cites W2898699548 @default.
• W4367665613 cites W2941033601 @default.
• W4367665613 cites W2975736685 @default.
• W4367665613 cites W3012377065 @default.
• W4367665613 cites W3015337416 @default.
• W4367665613 cites W3027228654 @default.
• W4367665613 cites W3028149335 @default.
• W4367665613 cites W3032282399 @default.
• W4367665613 cites W3082525510 @default.
• W4367665613 cites W3084360530 @default.
• W4367665613 cites W3110688801 @default.

• next