Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367673921> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W4367673921 abstract "Abstract Funding Acknowledgements Type of funding sources: None. Introduction and objectives Cardiac amyloidosis (CA) causes a restrictive cardiomyopathy, generally associated with symptoms and poor prognosis. Echocardiography plays a fundamental role in its diagnosis, and can also provide important prognostic information. Although left ventricular global longitudinal strain (GLS) has been studied using speckle-tracking echocardiography, and is known to be predictive of outcome, RV and LA involvement evaluated by deformation pattern is not yet well defined. The aim of this study is to characterize LV, RV and LA involvement in patients with CA, and to evaluate whether parameters of myocardial deformation of these cavities are correlated with functional class and/or number of hospitalizations in this group of patients. Material and methods We included 19 patients diagnosed with CA between 2021 and 2022. Demographic, clinical data and echocardiographic parameters were collected, including diastolic function parameters and study of myocardial deformation, using the speckle tracking technique of left ventricle, right ventricle, and left atrium. Statistical analysis was performed to evaluate the association between symptoms and imaging parameters. Results The mean age was 66 y.o. 77% male. The percentage of Cardiovascular risk factors was HTN 77%, DM 23%, dyslipidemia 23%. CAD 15%. Hospital admission in last year 23%. NYHA functional class II 23%. All echocardiographyc parameters and and significant correlations are showed in table 1. Regarding basic echocardiographic parameters, mean LV and RV systolic function was in normal range: LVEF 64%; RV TAPSE 21mm; mean Tricuspid annular peak systolic velocity 11,6cm/seg; RV fractional area change 40%. Concerning deformation parameters RV and LA parameters were decreased, RV free wall longitudinal strain -26,8%; RV four-chamber longitudinal strain -21,7%; LA reservoir strain 26,6%; LA conduit strain -15,1%; LA contractile strain -11%, although not significantly associated with a worse NYHA functional class or a higher number of hospital admissions, possibly due to a low sample size. In addition, a larger LA area and volume, shorter deceleration time and worse GLS correlated statistically significantly with a worse NYHA functional class, while a larger LA diameter and mean E/e' correlated with a higher number of admissions. Conclusions Echocardiography is a non-invasive, fast and simple diagnostic tool. Strain data from different cardiac chambers would allow early detection, or at least suspicion, of this entity. In addition, strain data of left atrium and right ventricle would allow to predict evolution and to be an important prognostic factor. Atrial and ventricular strain have promise for clinical utility." @default.
- W4367673921 created "2023-05-03" @default.
- W4367673921 creator A5012180890 @default.
- W4367673921 creator A5017389316 @default.
- W4367673921 creator A5048454867 @default.
- W4367673921 creator A5060442942 @default.
- W4367673921 creator A5083696185 @default.
- W4367673921 creator A5084209933 @default.
- W4367673921 date "2023-05-01" @default.
- W4367673921 modified "2023-10-14" @default.
- W4367673921 title "Correlation between heart failure symptoms and parameters of myocardial deformation in patients with cardiac amyloidosis" @default.
- W4367673921 doi "https://doi.org/10.1093/ehjacc/zuad036.031" @default.
- W4367673921 hasPublicationYear "2023" @default.
- W4367673921 type Work @default.
- W4367673921 citedByCount "0" @default.
- W4367673921 crossrefType "journal-article" @default.
- W4367673921 hasAuthorship W4367673921A5012180890 @default.
- W4367673921 hasAuthorship W4367673921A5017389316 @default.
- W4367673921 hasAuthorship W4367673921A5048454867 @default.
- W4367673921 hasAuthorship W4367673921A5060442942 @default.
- W4367673921 hasAuthorship W4367673921A5083696185 @default.
- W4367673921 hasAuthorship W4367673921A5084209933 @default.
- W4367673921 hasBestOaLocation W43676739211 @default.
- W4367673921 hasConcept C126322002 @default.
- W4367673921 hasConcept C164705383 @default.
- W4367673921 hasConcept C2777607188 @default.
- W4367673921 hasConcept C2778198053 @default.
- W4367673921 hasConcept C2778296771 @default.
- W4367673921 hasConcept C2778797674 @default.
- W4367673921 hasConcept C2778921608 @default.
- W4367673921 hasConcept C57900726 @default.
- W4367673921 hasConcept C71924100 @default.
- W4367673921 hasConcept C78085059 @default.
- W4367673921 hasConcept C84393581 @default.
- W4367673921 hasConceptScore W4367673921C126322002 @default.
- W4367673921 hasConceptScore W4367673921C164705383 @default.
- W4367673921 hasConceptScore W4367673921C2777607188 @default.
- W4367673921 hasConceptScore W4367673921C2778198053 @default.
- W4367673921 hasConceptScore W4367673921C2778296771 @default.
- W4367673921 hasConceptScore W4367673921C2778797674 @default.
- W4367673921 hasConceptScore W4367673921C2778921608 @default.
- W4367673921 hasConceptScore W4367673921C57900726 @default.
- W4367673921 hasConceptScore W4367673921C71924100 @default.
- W4367673921 hasConceptScore W4367673921C78085059 @default.
- W4367673921 hasConceptScore W4367673921C84393581 @default.
- W4367673921 hasIssue "Supplement_1" @default.
- W4367673921 hasLocation W43676739211 @default.
- W4367673921 hasOpenAccess W4367673921 @default.
- W4367673921 hasPrimaryLocation W43676739211 @default.
- W4367673921 hasRelatedWork W185626139 @default.
- W4367673921 hasRelatedWork W1964205598 @default.
- W4367673921 hasRelatedWork W2316342240 @default.
- W4367673921 hasRelatedWork W2347245660 @default.
- W4367673921 hasRelatedWork W2362265450 @default.
- W4367673921 hasRelatedWork W2375703560 @default.
- W4367673921 hasRelatedWork W2475222081 @default.
- W4367673921 hasRelatedWork W2912421895 @default.
- W4367673921 hasRelatedWork W2954999431 @default.
- W4367673921 hasRelatedWork W2965474825 @default.
- W4367673921 hasVolume "12" @default.
- W4367673921 isParatext "false" @default.
- W4367673921 isRetracted "false" @default.
- W4367673921 workType "article" @default.