FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367692564> ?p ?o ?g. }

• W4367692564 endingPage "355" @default.
• W4367692564 startingPage "343" @default.
• W4367692564 abstract "Remote ischemic conditioning (RIC) has been beneficial in laboratory studies of anthracycline cardiotoxicity, but its effects in patients is not established.The authors studied the effect of RIC on cardiac biomarkers and function during and after anthracycline chemotherapy.The ERIC-Onc study (Effect of Remote Ischaemic Conditioning in Oncology Patients; NCT02471885) was a randomized, single-blind, sham-controlled study of RIC at each chemotherapy cycle. The primary endpoint was troponin T (TnT) during chemotherapy and up to 1 year. Secondary outcomes included cardiac function, major adverse cardiovascular events (MACE), and MACE or cancer death. Cardiac myosin-binding-protein C (cMyC) was investigated in parallel with TnT.The study was prematurely halted after the evaluation of 55 patients (RIC n = 28, sham n = 27). Biomarkers increased from baseline to cycle 6 of chemotherapy for all patients (median TnT 6 [IQR: 4-9] ng/L to 33 [IQR: 16-36)] ng/L; P ≤ 0.001; cMyC 3 (IQR: 2-5) ng/L to 47 (IQR: 18-49) ng/L; P ≤ 0.001). Mixed-effects regression analysis for repeated measures showed no difference in TnT between the 2 groups (RIC vs sham, mean difference 3.15 ng/L; 95% CI: -0.04 to 6.33; P = 0.053), or cMyC (RIC vs sham, mean difference 4.17 ng/L; 95% CI: -0.12 to 8.45; P = 0.056). There were more MACE and cancer deaths in the RIC group (11 vs 3; HR: 0.25; 95% CI: 0.07-0.90; P = 0.034), with more cancer deaths (8 vs 1; HR: 0.21; 95% CI: 0.04-0.95; P = 0.043) at 1 year.TnT and cMyC significantly increased during anthracycline chemotherapy with 81% having a TnT ≥14 ng/L at cycle 6. RIC did not affect the rise in biomarkers, but there was a small increase in early cancer deaths, possibly related to the greater proportion of patients with metastatic disease randomized to the RIC group (54%vs 37%). (Effect of Remote Ischaemic Conditioning in Oncology Patients [ERIC-ONC]; NCT02471885)." @default.
• W4367692564 created "2023-05-03" @default.
• W4367692564 creator A5004024070 @default.
• W4367692564 creator A5009291823 @default.
• W4367692564 creator A5012907283 @default.
• W4367692564 creator A5014011356 @default.
• W4367692564 creator A5047892549 @default.
• W4367692564 creator A5054773163 @default.
• W4367692564 date "2023-06-01" @default.
• W4367692564 modified "2023-10-09" @default.
• W4367692564 title "Anthracyclines and Biomarkers of Myocardial Injury" @default.
• W4367692564 cites W1986235853 @default.
• W4367692564 cites W2004640561 @default.
• W4367692564 cites W2012517632 @default.
• W4367692564 cites W2056190116 @default.
• W4367692564 cites W2098268167 @default.
• W4367692564 cites W2104277034 @default.
• W4367692564 cites W2108811490 @default.
• W4367692564 cites W2109775164 @default.
• W4367692564 cites W2112357840 @default.
• W4367692564 cites W2122179672 @default.
• W4367692564 cites W2136272230 @default.
• W4367692564 cites W2142877037 @default.
• W4367692564 cites W2147646179 @default.
• W4367692564 cites W2181020396 @default.
• W4367692564 cites W2195724956 @default.
• W4367692564 cites W2281735941 @default.
• W4367692564 cites W2298838354 @default.
• W4367692564 cites W2341147279 @default.
• W4367692564 cites W2530199167 @default.
• W4367692564 cites W2596054539 @default.
• W4367692564 cites W2604605177 @default.
• W4367692564 cites W2803156669 @default.
• W4367692564 cites W2883422223 @default.
• W4367692564 cites W2909507870 @default.
• W4367692564 cites W2914574872 @default.
• W4367692564 cites W2972010323 @default.
• W4367692564 cites W2987112152 @default.
• W4367692564 cites W2995575990 @default.
• W4367692564 cites W3011400996 @default.
• W4367692564 cites W3017458749 @default.
• W4367692564 cites W3037672008 @default.
• W4367692564 cites W3041889642 @default.
• W4367692564 cites W3089951997 @default.
• W4367692564 doi "https://doi.org/10.1016/j.jaccao.2023.03.008" @default.
• W4367692564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37397080" @default.
• W4367692564 hasPublicationYear "2023" @default.
• W4367692564 type Work @default.
• W4367692564 citedByCount "2" @default.
• W4367692564 countsByYear W43676925642023 @default.
• W4367692564 crossrefType "journal-article" @default.
• W4367692564 hasAuthorship W4367692564A5004024070 @default.
• W4367692564 hasAuthorship W4367692564A5009291823 @default.
• W4367692564 hasAuthorship W4367692564A5012907283 @default.
• W4367692564 hasAuthorship W4367692564A5014011356 @default.
• W4367692564 hasAuthorship W4367692564A5047892549 @default.
• W4367692564 hasAuthorship W4367692564A5054773163 @default.
• W4367692564 hasBestOaLocation W43676925641 @default.
• W4367692564 hasConcept C111566952 @default.
• W4367692564 hasConcept C115725540 @default.
• W4367692564 hasConcept C121608353 @default.
• W4367692564 hasConcept C126322002 @default.
• W4367692564 hasConcept C143998085 @default.
• W4367692564 hasConcept C164705383 @default.
• W4367692564 hasConcept C168563851 @default.
• W4367692564 hasConcept C203092338 @default.
• W4367692564 hasConcept C2776694085 @default.
• W4367692564 hasConcept C2776802502 @default.
• W4367692564 hasConcept C2778198053 @default.
• W4367692564 hasConcept C2778233292 @default.
• W4367692564 hasConcept C2780400711 @default.
• W4367692564 hasConcept C2780739214 @default.
• W4367692564 hasConcept C36036425 @default.
• W4367692564 hasConcept C500558357 @default.
• W4367692564 hasConcept C530470458 @default.
• W4367692564 hasConcept C71924100 @default.
• W4367692564 hasConcept C90924648 @default.
• W4367692564 hasConceptScore W4367692564C111566952 @default.
• W4367692564 hasConceptScore W4367692564C115725540 @default.
• W4367692564 hasConceptScore W4367692564C121608353 @default.
• W4367692564 hasConceptScore W4367692564C126322002 @default.
• W4367692564 hasConceptScore W4367692564C143998085 @default.
• W4367692564 hasConceptScore W4367692564C164705383 @default.
• W4367692564 hasConceptScore W4367692564C168563851 @default.
• W4367692564 hasConceptScore W4367692564C203092338 @default.
• W4367692564 hasConceptScore W4367692564C2776694085 @default.
• W4367692564 hasConceptScore W4367692564C2776802502 @default.
• W4367692564 hasConceptScore W4367692564C2778198053 @default.
• W4367692564 hasConceptScore W4367692564C2778233292 @default.
• W4367692564 hasConceptScore W4367692564C2780400711 @default.
• W4367692564 hasConceptScore W4367692564C2780739214 @default.
• W4367692564 hasConceptScore W4367692564C36036425 @default.
• W4367692564 hasConceptScore W4367692564C500558357 @default.
• W4367692564 hasConceptScore W4367692564C530470458 @default.
• W4367692564 hasConceptScore W4367692564C71924100 @default.
• W4367692564 hasConceptScore W4367692564C90924648 @default.
• W4367692564 hasIssue "3" @default.
• W4367692564 hasLocation W43676925641 @default.

• next