Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367835213> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4367835213 endingPage "74" @default.
- W4367835213 startingPage "67" @default.
- W4367835213 abstract "AimTo evaluate the relationship between serological indicators of Herpesviridae infection and evolution of symptoms in children with chronic spontaneous urticaria (CSU).MethodsIn this observational study, consecutive children with CSU underwent, at presentation, clinical and laboratory work-up, autologous serum skin test (ASST) to identify autoimmune urticaria (CAU), disease severity assessment (urticaria activity score 7, UAS7), serological diagnostics for Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpes virus-6 (HHV-6), and parvovirus B19, as well as for Mycoplasma pneumoniae and Chlamydia pneumoniae. Children were re-assessed at 1, 6, and 12 months after the commencement of antihistamine/antileukotriene treatment.ResultsNone of the 56 included children had an acute CMV/EBV or HHV-6 infection, but 17 (30.3%) had IgG antibodies against CMV, EBV, or HHV-6 (five were also seropositive for parvovirus B19); 24 (42.8%) suffered from CAU; and 9 (16.1%) were seropositive for Mycoplasma/Chlamydia pneumoniae. The initial symptom severity was moderate-to-severe (UAS7 quartiles 18-32) and comparable between Herpesviridae-seropositive and Herpesviridae-seronegative patients. At 1, 6, and 12 months, UAS7 was consistently higher in seropositive children. In a multivariable analysis (adjusted for age, baseline UAS7, ASST, mean platelet volume, and other serology), Herpesviridae seropositivity was associated with higher UAS scores: mean difference 4.2 score points (95% confidence interval 0.5-7.9; Bayes estimate 4.2, 95% credible interval 1.2-7.3) in a mixed model for repeated measures. This estimate was comparable between children with positive (CAU) and negative (CSU) ASST.ConclusionA history of CMV/EBV/HHV-6 infection might contribute to a slower-resolving CSU in children." @default.
- W4367835213 created "2023-05-04" @default.
- W4367835213 creator A5011590109 @default.
- W4367835213 creator A5014187299 @default.
- W4367835213 creator A5049822051 @default.
- W4367835213 date "2023-04-01" @default.
- W4367835213 modified "2023-10-14" @default.
- W4367835213 title "Association between serological indicators of past contacts with Herpesviridae and a slower resolution of chronic spontaneous urticaria in children" @default.
- W4367835213 cites W1820466493 @default.
- W4367835213 cites W1980373508 @default.
- W4367835213 cites W2027664945 @default.
- W4367835213 cites W2081506756 @default.
- W4367835213 cites W2083492616 @default.
- W4367835213 cites W2149082019 @default.
- W4367835213 cites W2341125252 @default.
- W4367835213 cites W2537397002 @default.
- W4367835213 cites W2590970441 @default.
- W4367835213 cites W2614617566 @default.
- W4367835213 cites W2768085516 @default.
- W4367835213 cites W2791703900 @default.
- W4367835213 cites W2810953097 @default.
- W4367835213 cites W2911405925 @default.
- W4367835213 cites W2917662849 @default.
- W4367835213 cites W2923527542 @default.
- W4367835213 cites W2934481534 @default.
- W4367835213 cites W2973061015 @default.
- W4367835213 cites W3015842317 @default.
- W4367835213 cites W3031049166 @default.
- W4367835213 cites W3150943992 @default.
- W4367835213 doi "https://doi.org/10.3325/cmj.2023.64.67" @default.
- W4367835213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37131308" @default.
- W4367835213 hasPublicationYear "2023" @default.
- W4367835213 type Work @default.
- W4367835213 citedByCount "0" @default.
- W4367835213 crossrefType "journal-article" @default.
- W4367835213 hasAuthorship W4367835213A5011590109 @default.
- W4367835213 hasAuthorship W4367835213A5014187299 @default.
- W4367835213 hasAuthorship W4367835213A5049822051 @default.
- W4367835213 hasBestOaLocation W43678352131 @default.
- W4367835213 hasConcept C126322002 @default.
- W4367835213 hasConcept C159654299 @default.
- W4367835213 hasConcept C203014093 @default.
- W4367835213 hasConcept C2522874641 @default.
- W4367835213 hasConcept C2776409557 @default.
- W4367835213 hasConcept C2777399126 @default.
- W4367835213 hasConcept C2777732132 @default.
- W4367835213 hasConcept C2777914695 @default.
- W4367835213 hasConcept C2779215961 @default.
- W4367835213 hasConcept C2779820661 @default.
- W4367835213 hasConcept C2780122209 @default.
- W4367835213 hasConcept C2780727368 @default.
- W4367835213 hasConcept C45189115 @default.
- W4367835213 hasConcept C71924100 @default.
- W4367835213 hasConceptScore W4367835213C126322002 @default.
- W4367835213 hasConceptScore W4367835213C159654299 @default.
- W4367835213 hasConceptScore W4367835213C203014093 @default.
- W4367835213 hasConceptScore W4367835213C2522874641 @default.
- W4367835213 hasConceptScore W4367835213C2776409557 @default.
- W4367835213 hasConceptScore W4367835213C2777399126 @default.
- W4367835213 hasConceptScore W4367835213C2777732132 @default.
- W4367835213 hasConceptScore W4367835213C2777914695 @default.
- W4367835213 hasConceptScore W4367835213C2779215961 @default.
- W4367835213 hasConceptScore W4367835213C2779820661 @default.
- W4367835213 hasConceptScore W4367835213C2780122209 @default.
- W4367835213 hasConceptScore W4367835213C2780727368 @default.
- W4367835213 hasConceptScore W4367835213C45189115 @default.
- W4367835213 hasConceptScore W4367835213C71924100 @default.
- W4367835213 hasIssue "2" @default.
- W4367835213 hasLocation W43678352131 @default.
- W4367835213 hasLocation W43678352132 @default.
- W4367835213 hasLocation W43678352133 @default.
- W4367835213 hasOpenAccess W4367835213 @default.
- W4367835213 hasPrimaryLocation W43678352131 @default.
- W4367835213 hasRelatedWork W2057013135 @default.
- W4367835213 hasRelatedWork W2136073971 @default.
- W4367835213 hasRelatedWork W2136126662 @default.
- W4367835213 hasRelatedWork W2152981939 @default.
- W4367835213 hasRelatedWork W2157600163 @default.
- W4367835213 hasRelatedWork W2194230682 @default.
- W4367835213 hasRelatedWork W2409028883 @default.
- W4367835213 hasRelatedWork W2416536807 @default.
- W4367835213 hasRelatedWork W2985581640 @default.
- W4367835213 hasRelatedWork W4311797974 @default.
- W4367835213 hasVolume "64" @default.
- W4367835213 isParatext "false" @default.
- W4367835213 isRetracted "false" @default.
- W4367835213 workType "article" @default.