Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367837335> ?p ?o ?g. }
- W4367837335 endingPage "123014" @default.
- W4367837335 startingPage "123014" @default.
- W4367837335 abstract "Bacterial infection has been considered as a significant obstacle for wound healing. Nitric oxide (NO), as a novel alternative for antibiotics, has emerged as a promising antibacterial agent. However, the precise spatiotemporal controlled release of NO still remains a major challenge. Herein, a near-infrared (NIR) light triggered NO release nanoplatform (designated as PB-NO@PDA-PHMB) with enhanced broad-spectrum antibacterial and anti-biofilm properties was constructed. Given that PB-NO@PDA-PHMB has strong absorption in the NIR region and exhibits excellent photothermal effect, it can rapidly trigger NO release by NIR irradiation. PB-NO@PDA-PHMB can effectively contact and capture bacteria, and then exhibit synergistic effect of photothermal and gas therapy. In vitro and in vivo experiments indicated that PB-NO@PDA-PHMB exhibited excellent biocompatibility, satisfactory synergistic antibacterial efficacy and the capability of accelerating wound healing. Under NIR irradiation (808 nm, 1 W cm−2, 7 min), PB-NO@PDA-PHMB (80 μg mL−1) achieved 100% bactericidal activity against both Gram-negative bacteria Escherichia coli (E. coli) and Gram-positive bacteria Staphyloccocus aureus (S. aureus), removed 58.94% of S. aureus biofilm. Therefore, this all-in-one antibacterial nanoplatform with high NIR responsiveness provides a promising antibiotic-free strategy for bacterial infection treatment." @default.
- W4367837335 created "2023-05-04" @default.
- W4367837335 creator A5010479652 @default.
- W4367837335 creator A5020199151 @default.
- W4367837335 creator A5023736408 @default.
- W4367837335 creator A5039009774 @default.
- W4367837335 creator A5063931826 @default.
- W4367837335 creator A5081425657 @default.
- W4367837335 date "2023-06-01" @default.
- W4367837335 modified "2023-09-27" @default.
- W4367837335 title "PHMB modified photothermally triggered nitric oxide release nanoplatform for precise synergistic therapy of wound bacterial infections" @default.
- W4367837335 cites W1963940127 @default.
- W4367837335 cites W2033156964 @default.
- W4367837335 cites W2076497970 @default.
- W4367837335 cites W2154150171 @default.
- W4367837335 cites W2594669178 @default.
- W4367837335 cites W2688985511 @default.
- W4367837335 cites W2755219721 @default.
- W4367837335 cites W2796394769 @default.
- W4367837335 cites W2896969491 @default.
- W4367837335 cites W2944543750 @default.
- W4367837335 cites W2945855775 @default.
- W4367837335 cites W2953384298 @default.
- W4367837335 cites W2960758355 @default.
- W4367837335 cites W2991661281 @default.
- W4367837335 cites W2999819669 @default.
- W4367837335 cites W3006762758 @default.
- W4367837335 cites W3010589531 @default.
- W4367837335 cites W3011607406 @default.
- W4367837335 cites W3034791748 @default.
- W4367837335 cites W3035215984 @default.
- W4367837335 cites W3041715525 @default.
- W4367837335 cites W3047136164 @default.
- W4367837335 cites W3072334995 @default.
- W4367837335 cites W3109462015 @default.
- W4367837335 cites W3112713656 @default.
- W4367837335 cites W3116219345 @default.
- W4367837335 cites W3130496021 @default.
- W4367837335 cites W3158487069 @default.
- W4367837335 cites W3159635531 @default.
- W4367837335 cites W3160367452 @default.
- W4367837335 cites W3173747963 @default.
- W4367837335 cites W3174167338 @default.
- W4367837335 cites W3174320609 @default.
- W4367837335 cites W3175228952 @default.
- W4367837335 cites W3196038262 @default.
- W4367837335 cites W3197750777 @default.
- W4367837335 cites W3198862468 @default.
- W4367837335 cites W3201037629 @default.
- W4367837335 cites W3201130220 @default.
- W4367837335 cites W3202195386 @default.
- W4367837335 cites W3205094902 @default.
- W4367837335 cites W3209908006 @default.
- W4367837335 cites W3211858418 @default.
- W4367837335 cites W3215154339 @default.
- W4367837335 cites W3216741582 @default.
- W4367837335 cites W4200286445 @default.
- W4367837335 cites W4210617720 @default.
- W4367837335 cites W4211009618 @default.
- W4367837335 cites W4212772261 @default.
- W4367837335 cites W4214725163 @default.
- W4367837335 cites W4214864098 @default.
- W4367837335 cites W4220859742 @default.
- W4367837335 cites W4221062461 @default.
- W4367837335 cites W4282927795 @default.
- W4367837335 cites W4283025817 @default.
- W4367837335 cites W4283763856 @default.
- W4367837335 cites W4288809101 @default.
- W4367837335 cites W4306248004 @default.
- W4367837335 doi "https://doi.org/10.1016/j.ijpharm.2023.123014" @default.
- W4367837335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37146954" @default.
- W4367837335 hasPublicationYear "2023" @default.
- W4367837335 type Work @default.
- W4367837335 citedByCount "0" @default.
- W4367837335 crossrefType "journal-article" @default.
- W4367837335 hasAuthorship W4367837335A5010479652 @default.
- W4367837335 hasAuthorship W4367837335A5020199151 @default.
- W4367837335 hasAuthorship W4367837335A5023736408 @default.
- W4367837335 hasAuthorship W4367837335A5039009774 @default.
- W4367837335 hasAuthorship W4367837335A5063931826 @default.
- W4367837335 hasAuthorship W4367837335A5081425657 @default.
- W4367837335 hasConcept C104317684 @default.
- W4367837335 hasConcept C150903083 @default.
- W4367837335 hasConcept C171250308 @default.
- W4367837335 hasConcept C178790620 @default.
- W4367837335 hasConcept C182606246 @default.
- W4367837335 hasConcept C185592680 @default.
- W4367837335 hasConcept C192562407 @default.
- W4367837335 hasConcept C203014093 @default.
- W4367837335 hasConcept C207001950 @default.
- W4367837335 hasConcept C2777230088 @default.
- W4367837335 hasConcept C2777742735 @default.
- W4367837335 hasConcept C2779489039 @default.
- W4367837335 hasConcept C2780104969 @default.
- W4367837335 hasConcept C2780269544 @default.
- W4367837335 hasConcept C501593827 @default.
- W4367837335 hasConcept C519581460 @default.
- W4367837335 hasConcept C523546767 @default.