Matches in SemOpenAlex for { <https://semopenalex.org/work/W4367839771> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4367839771 abstract "After nearly a decade of new data, the Evidence-Based Consensus Conference Statement from the AAPS was updated for prophylactic systemic antibiotics to prevent surgical site infections (SSI). Pharmacotherapeutic concepts using antimicrobial stewardships were applied for clinical interpretation and management to optimize patient outcomes and minimize resistance.PRISMA, Cochrane, and GRADE certainty of evidence guidelines were implemented for the structure and synthesis of the review. PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were systematically and independently searched for randomized controlled trials (RCTs). We included patients that had Plastic and Reconstructive Surgery and were treated with prophylactic systemic antibiotics administered perioperatively (preoperative, intraoperative, postoperative). Comparisons were made between active interventions and/or non-active interventions (placebo) at different prespecified durations to determine the development of an (SSI). Meta-analyses were performed.We included 138 RCTs that met eligibility criteria. RCTs consisted of 18 Breast, 10 Cosmetic, 21 Hand/Peripheral Nerve, 61 Pediatric/Craniofacial, and 41 Reconstructive studies. We further examined bacterial data extracted from studies for patients that did and did not take prophylactic systemic antibiotics for prevention of SSI. Clinical recommendations were provided using Level-I evidence.Surgeons have long been overprescribing systemic antibiotic prophylaxis in Plastic and Reconstructive Surgery. Evidence supports antibiotic prophylaxis to prevent SSI for specific indications and durations. Prolonged antibiotic use has not been linked to reductions in SSIs and misuse may increase the bacterial diversity of infections. Greater efforts should focus on transitioning from practice-based medicine to pharmacotherapeutic evidence-based medicine." @default.
- W4367839771 created "2023-05-04" @default.
- W4367839771 creator A5007220205 @default.
- W4367839771 creator A5008597448 @default.
- W4367839771 creator A5014887568 @default.
- W4367839771 creator A5030592684 @default.
- W4367839771 creator A5030871345 @default.
- W4367839771 creator A5065051021 @default.
- W4367839771 date "2023-05-02" @default.
- W4367839771 modified "2023-10-10" @default.
- W4367839771 title "Evidence-Based Medicine: Systemic Perioperative Antibiotic Prophylaxis for Prevention of Surgical-Site Infections in Plastic and Reconstructive Surgery" @default.
- W4367839771 doi "https://doi.org/10.1097/prs.0000000000010608" @default.
- W4367839771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37141459" @default.
- W4367839771 hasPublicationYear "2023" @default.
- W4367839771 type Work @default.
- W4367839771 citedByCount "1" @default.
- W4367839771 crossrefType "journal-article" @default.
- W4367839771 hasAuthorship W4367839771A5007220205 @default.
- W4367839771 hasAuthorship W4367839771A5008597448 @default.
- W4367839771 hasAuthorship W4367839771A5014887568 @default.
- W4367839771 hasAuthorship W4367839771A5030592684 @default.
- W4367839771 hasAuthorship W4367839771A5030871345 @default.
- W4367839771 hasAuthorship W4367839771A5065051021 @default.
- W4367839771 hasConcept C116558999 @default.
- W4367839771 hasConcept C141071460 @default.
- W4367839771 hasConcept C142724271 @default.
- W4367839771 hasConcept C168563851 @default.
- W4367839771 hasConcept C17744445 @default.
- W4367839771 hasConcept C177713679 @default.
- W4367839771 hasConcept C189708586 @default.
- W4367839771 hasConcept C19648533 @default.
- W4367839771 hasConcept C199539241 @default.
- W4367839771 hasConcept C204787440 @default.
- W4367839771 hasConcept C2776478404 @default.
- W4367839771 hasConcept C2778602436 @default.
- W4367839771 hasConcept C2779473830 @default.
- W4367839771 hasConcept C31174226 @default.
- W4367839771 hasConcept C501593827 @default.
- W4367839771 hasConcept C71924100 @default.
- W4367839771 hasConcept C86803240 @default.
- W4367839771 hasConcept C89423630 @default.
- W4367839771 hasConceptScore W4367839771C116558999 @default.
- W4367839771 hasConceptScore W4367839771C141071460 @default.
- W4367839771 hasConceptScore W4367839771C142724271 @default.
- W4367839771 hasConceptScore W4367839771C168563851 @default.
- W4367839771 hasConceptScore W4367839771C17744445 @default.
- W4367839771 hasConceptScore W4367839771C177713679 @default.
- W4367839771 hasConceptScore W4367839771C189708586 @default.
- W4367839771 hasConceptScore W4367839771C19648533 @default.
- W4367839771 hasConceptScore W4367839771C199539241 @default.
- W4367839771 hasConceptScore W4367839771C204787440 @default.
- W4367839771 hasConceptScore W4367839771C2776478404 @default.
- W4367839771 hasConceptScore W4367839771C2778602436 @default.
- W4367839771 hasConceptScore W4367839771C2779473830 @default.
- W4367839771 hasConceptScore W4367839771C31174226 @default.
- W4367839771 hasConceptScore W4367839771C501593827 @default.
- W4367839771 hasConceptScore W4367839771C71924100 @default.
- W4367839771 hasConceptScore W4367839771C86803240 @default.
- W4367839771 hasConceptScore W4367839771C89423630 @default.
- W4367839771 hasLocation W43678397711 @default.
- W4367839771 hasLocation W43678397712 @default.
- W4367839771 hasOpenAccess W4367839771 @default.
- W4367839771 hasPrimaryLocation W43678397711 @default.
- W4367839771 hasRelatedWork W1996551696 @default.
- W4367839771 hasRelatedWork W2011976818 @default.
- W4367839771 hasRelatedWork W2016006997 @default.
- W4367839771 hasRelatedWork W2338076166 @default.
- W4367839771 hasRelatedWork W2418011111 @default.
- W4367839771 hasRelatedWork W2906553061 @default.
- W4367839771 hasRelatedWork W2999349737 @default.
- W4367839771 hasRelatedWork W4205460667 @default.
- W4367839771 hasRelatedWork W4306946280 @default.
- W4367839771 hasRelatedWork W4316467617 @default.
- W4367839771 hasVolume "Publish Ahead of Print" @default.
- W4367839771 isParatext "false" @default.
- W4367839771 isRetracted "false" @default.
- W4367839771 workType "article" @default.