FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4368361670> ?p ?o ?g. }

• W4368361670 endingPage "627" @default.
• W4368361670 startingPage "615" @default.
• W4368361670 abstract "Aim: Among 15 human (h) carbonic anhydrase (CA; EC 4.2.1.1) isoforms, two (hCA IX and XII) play important roles in the growth and survival of tumor cells, making them therapeutic targets for cancer treatment. This study aimed to develop novel sulfonamide-based compounds as selective hCA IX and XII inhibitors. Materials & methods: A library of novel N-sulfonyl carbamimidothioates was obtained for CA inhibitory activity studies against four hCA isoforms. Results: None of the developed compounds displayed inhibitory potential against off-target isoforms hCA I and II. However, they effectively inhibited tumor-associated hCA IX and XII. Conclusion: The present study suggests potent lead compounds as selective hCA IX and XII inhibitors with anticancer activity." @default.
• W4368361670 created "2023-05-05" @default.
• W4368361670 creator A5015328975 @default.
• W4368361670 creator A5016753502 @default.
• W4368361670 creator A5035013697 @default.
• W4368361670 creator A5036969494 @default.
• W4368361670 creator A5068404198 @default.
• W4368361670 date "2023-04-01" @default.
• W4368361670 modified "2023-10-05" @default.
• W4368361670 title "Investigation of carbonic anhydrase inhibitory potency of (<i>Z/E</i>)-alkyl <i>N</i>‘-benzyl-<i>N</i>-(arylsulfonyl)-carbamimidothioates" @default.
• W4368361670 cites W1523479214 @default.
• W4368361670 cites W1573899446 @default.
• W4368361670 cites W1982430777 @default.
• W4368361670 cites W1991845210 @default.
• W4368361670 cites W2042007637 @default.
• W4368361670 cites W2045927961 @default.
• W4368361670 cites W2047178318 @default.
• W4368361670 cites W2067592933 @default.
• W4368361670 cites W2080860795 @default.
• W4368361670 cites W2088350865 @default.
• W4368361670 cites W2097524602 @default.
• W4368361670 cites W2111775991 @default.
• W4368361670 cites W2119752391 @default.
• W4368361670 cites W2120859012 @default.
• W4368361670 cites W2153412842 @default.
• W4368361670 cites W2465060989 @default.
• W4368361670 cites W2604420724 @default.
• W4368361670 cites W2740987920 @default.
• W4368361670 cites W2771348893 @default.
• W4368361670 cites W2792428864 @default.
• W4368361670 cites W2792809240 @default.
• W4368361670 cites W2795286490 @default.
• W4368361670 cites W2805727885 @default.
• W4368361670 cites W2807235413 @default.
• W4368361670 cites W2891768838 @default.
• W4368361670 cites W2896867935 @default.
• W4368361670 cites W2901194941 @default.
• W4368361670 cites W2951754707 @default.
• W4368361670 cites W3016605747 @default.
• W4368361670 cites W3018468142 @default.
• W4368361670 cites W3111292866 @default.
• W4368361670 cites W3157475894 @default.
• W4368361670 cites W3197985339 @default.
• W4368361670 cites W4281969170 @default.
• W4368361670 cites W4307721266 @default.
• W4368361670 cites W4308973977 @default.
• W4368361670 cites W4309309644 @default.
• W4368361670 cites W4315619817 @default.
• W4368361670 cites W4315621202 @default.
• W4368361670 cites W4317871327 @default.
• W4368361670 cites W4318671183 @default.
• W4368361670 cites W4319827408 @default.
• W4368361670 doi "https://doi.org/10.4155/fmc-2022-0287" @default.
• W4368361670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37140057" @default.
• W4368361670 hasPublicationYear "2023" @default.
• W4368361670 type Work @default.
• W4368361670 citedByCount "1" @default.
• W4368361670 countsByYear W43683616702023 @default.
• W4368361670 crossrefType "journal-article" @default.
• W4368361670 hasAuthorship W4368361670A5015328975 @default.
• W4368361670 hasAuthorship W4368361670A5016753502 @default.
• W4368361670 hasAuthorship W4368361670A5035013697 @default.
• W4368361670 hasAuthorship W4368361670A5036969494 @default.
• W4368361670 hasAuthorship W4368361670A5068404198 @default.
• W4368361670 hasConcept C104317684 @default.
• W4368361670 hasConcept C126322002 @default.
• W4368361670 hasConcept C17077164 @default.
• W4368361670 hasConcept C178790620 @default.
• W4368361670 hasConcept C181199279 @default.
• W4368361670 hasConcept C185592680 @default.
• W4368361670 hasConcept C202751555 @default.
• W4368361670 hasConcept C2775914622 @default.
• W4368361670 hasConcept C2780263894 @default.
• W4368361670 hasConcept C2781039511 @default.
• W4368361670 hasConcept C2911210155 @default.
• W4368361670 hasConcept C53345823 @default.
• W4368361670 hasConcept C55493867 @default.
• W4368361670 hasConcept C57992300 @default.
• W4368361670 hasConcept C71240020 @default.
• W4368361670 hasConcept C71924100 @default.
• W4368361670 hasConcept C86803240 @default.
• W4368361670 hasConcept C87906975 @default.
• W4368361670 hasConcept C98274493 @default.
• W4368361670 hasConceptScore W4368361670C104317684 @default.
• W4368361670 hasConceptScore W4368361670C126322002 @default.
• W4368361670 hasConceptScore W4368361670C17077164 @default.
• W4368361670 hasConceptScore W4368361670C178790620 @default.
• W4368361670 hasConceptScore W4368361670C181199279 @default.
• W4368361670 hasConceptScore W4368361670C185592680 @default.
• W4368361670 hasConceptScore W4368361670C202751555 @default.
• W4368361670 hasConceptScore W4368361670C2775914622 @default.
• W4368361670 hasConceptScore W4368361670C2780263894 @default.
• W4368361670 hasConceptScore W4368361670C2781039511 @default.
• W4368361670 hasConceptScore W4368361670C2911210155 @default.
• W4368361670 hasConceptScore W4368361670C53345823 @default.
• W4368361670 hasConceptScore W4368361670C55493867 @default.
• W4368361670 hasConceptScore W4368361670C57992300 @default.
• W4368361670 hasConceptScore W4368361670C71240020 @default.

• next