FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4368377277> ?p ?o ?g. }

• W4368377277 abstract "Introduction Serum Cystatin C level, an indication of kidney function, has been implicated in the pathogenesis of Alzheimer’s disease and cognitive impairment. In this cross-sectional study, we looked into the relation between serum Cystatin C levels and cognition in a group of U.S. older adults. Method The data of this study were from the National Health and Nutrition Examination Survey (NHANES) 1999–2002. A total of 4,832 older adults aged ≥60 who met the inclusion criteria were included. The Dade Behring N Latex Cystatin C assay, which is a particle-enhanced nephelometric assay (PENIA), was utilized to assess Cystatin C levels in participants’ blood samples. Participants’ cognition was examined using the digit symbol substitution test (DSST). Z -scores of the DSST were calculated based on sample means and standard deviations (SD). To investigate the relationships between the quartiles of serum Cystatin C level and DSST z scores, multiple linear regression models were developed while controlling for age, sex, race/ethnicity, and education. Results The average age of the participants was 71.1 (SD 7.8). The participants were about half female (50.5%), non-Hispanic White (61.2%), and (36.1%) who had completed at least some college. They had an average serum Cystatin C level of 1.0 mg/dl (SD 0.44). After performing multiple linear regression with a reference group consisting of participants in quartile one of plasma Cystatin C levels, we found that serum Cystatin C levels in quartiles three and four were independently associated with lower DSST z scores (β = −0.059, 95% CI −0.200 to −0.074 and β = −0.108, 95% CI −0.319 to −0.184, respectively). Conclusion Higher serum Cystatin C level is associated with worse processing speed, sustained attention, and working memory in older adults. Cystatin C level may be a biomarker for cognitive decline in older adults." @default.
• W4368377277 created "2023-05-05" @default.
• W4368377277 creator A5017101244 @default.
• W4368377277 creator A5025913683 @default.
• W4368377277 creator A5035988060 @default.
• W4368377277 creator A5048687499 @default.
• W4368377277 creator A5087592842 @default.
• W4368377277 date "2023-05-03" @default.
• W4368377277 modified "2023-10-05" @default.
• W4368377277 title "Association between serum cystatin C level and cognition in older adults: a cross-sectional analysis" @default.
• W4368377277 cites W1590309046 @default.
• W4368377277 cites W1597629772 @default.
• W4368377277 cites W1605885548 @default.
• W4368377277 cites W1940569337 @default.
• W4368377277 cites W1969387743 @default.
• W4368377277 cites W2022184632 @default.
• W4368377277 cites W2030094387 @default.
• W4368377277 cites W2039502252 @default.
• W4368377277 cites W2047699811 @default.
• W4368377277 cites W2049931789 @default.
• W4368377277 cites W2062279381 @default.
• W4368377277 cites W2069518930 @default.
• W4368377277 cites W2079589045 @default.
• W4368377277 cites W2121883535 @default.
• W4368377277 cites W2123775770 @default.
• W4368377277 cites W2133488570 @default.
• W4368377277 cites W2140031808 @default.
• W4368377277 cites W2160097311 @default.
• W4368377277 cites W2328066096 @default.
• W4368377277 cites W2402991504 @default.
• W4368377277 cites W2418109200 @default.
• W4368377277 cites W2432488913 @default.
• W4368377277 cites W2471096910 @default.
• W4368377277 cites W2587302224 @default.
• W4368377277 cites W2793151523 @default.
• W4368377277 cites W2800893684 @default.
• W4368377277 cites W2888254436 @default.
• W4368377277 cites W2962602583 @default.
• W4368377277 cites W2994904265 @default.
• W4368377277 cites W3046275966 @default.
• W4368377277 cites W3093148829 @default.
• W4368377277 cites W4210785180 @default.
• W4368377277 cites W4251443752 @default.
• W4368377277 doi "https://doi.org/10.3389/fnins.2023.1200763" @default.
• W4368377277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37207178" @default.
• W4368377277 hasPublicationYear "2023" @default.
• W4368377277 type Work @default.
• W4368377277 citedByCount "1" @default.
• W4368377277 crossrefType "journal-article" @default.
• W4368377277 hasAuthorship W4368377277A5017101244 @default.
• W4368377277 hasAuthorship W4368377277A5025913683 @default.
• W4368377277 hasAuthorship W4368377277A5035988060 @default.
• W4368377277 hasAuthorship W4368377277A5048687499 @default.
• W4368377277 hasAuthorship W4368377277A5087592842 @default.
• W4368377277 hasBestOaLocation W43683772771 @default.
• W4368377277 hasConcept C119857082 @default.
• W4368377277 hasConcept C126322002 @default.
• W4368377277 hasConcept C134018914 @default.
• W4368377277 hasConcept C142052008 @default.
• W4368377277 hasConcept C142724271 @default.
• W4368377277 hasConcept C159641895 @default.
• W4368377277 hasConcept C204787440 @default.
• W4368377277 hasConcept C27081682 @default.
• W4368377277 hasConcept C2777965283 @default.
• W4368377277 hasConcept C2779548226 @default.
• W4368377277 hasConcept C2779874844 @default.
• W4368377277 hasConcept C2780412452 @default.
• W4368377277 hasConcept C2908647359 @default.
• W4368377277 hasConcept C41008148 @default.
• W4368377277 hasConcept C44249647 @default.
• W4368377277 hasConcept C48921125 @default.
• W4368377277 hasConcept C68443243 @default.
• W4368377277 hasConcept C71924100 @default.
• W4368377277 hasConcept C90924648 @default.
• W4368377277 hasConcept C99454951 @default.
• W4368377277 hasConceptScore W4368377277C119857082 @default.
• W4368377277 hasConceptScore W4368377277C126322002 @default.
• W4368377277 hasConceptScore W4368377277C134018914 @default.
• W4368377277 hasConceptScore W4368377277C142052008 @default.
• W4368377277 hasConceptScore W4368377277C142724271 @default.
• W4368377277 hasConceptScore W4368377277C159641895 @default.
• W4368377277 hasConceptScore W4368377277C204787440 @default.
• W4368377277 hasConceptScore W4368377277C27081682 @default.
• W4368377277 hasConceptScore W4368377277C2777965283 @default.
• W4368377277 hasConceptScore W4368377277C2779548226 @default.
• W4368377277 hasConceptScore W4368377277C2779874844 @default.
• W4368377277 hasConceptScore W4368377277C2780412452 @default.
• W4368377277 hasConceptScore W4368377277C2908647359 @default.
• W4368377277 hasConceptScore W4368377277C41008148 @default.
• W4368377277 hasConceptScore W4368377277C44249647 @default.
• W4368377277 hasConceptScore W4368377277C48921125 @default.
• W4368377277 hasConceptScore W4368377277C68443243 @default.
• W4368377277 hasConceptScore W4368377277C71924100 @default.
• W4368377277 hasConceptScore W4368377277C90924648 @default.
• W4368377277 hasConceptScore W4368377277C99454951 @default.
• W4368377277 hasLocation W43683772771 @default.
• W4368377277 hasLocation W43683772772 @default.
• W4368377277 hasLocation W43683772773 @default.
• W4368377277 hasOpenAccess W4368377277 @default.
• W4368377277 hasPrimaryLocation W43683772771 @default.

• next