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- W4372203436 endingPage "105221" @default.
- W4372203436 startingPage "105221" @default.
- W4372203436 abstract "Event-related potentials (ERPs) represent the cortical processing of sensory, motor or cognitive functions invoked by particular events or stimuli. A current theory posits that the catecholaminergic neurotransmitters dopamine (DA) and norepinephrine (NE) modulate a number of endogenous ERPs during various cognitive processes. This manuscript aims to evaluate a leading neurotransmitter hypothesis with a systematic overview and meta-analysis of pharmacologic DA and NE manipulation of specific ERPs in healthy subjects during executive function. Specifically, the frontally-distributed P3a, N2, and Ne/ERN (or error-related negativity) are supposedly modulated primarily by DA, whereas the parietally-distributed P3b is thought to be modulated by NE. Based on preceding research, we refer to this distinction between frontally-distributed DA-sensitive and parietally-distributed NE-sensitive ERP components as the Extended Neurobiological Polich (ENP) hypothesis. Our systematic review and meta-analysis indicate that this distinction is too simplistic and many factors interact with DA and NE to influence these specific ERPs. These may include genetic factors, the specific cognitive processes engaged, or elements of study design, i.e. session or sequence effects or data-analysis strategies." @default.
- W4372203436 created "2023-05-07" @default.
- W4372203436 creator A5030986324 @default.
- W4372203436 creator A5037788060 @default.
- W4372203436 creator A5081883481 @default.
- W4372203436 date "2023-08-01" @default.
- W4372203436 modified "2023-10-15" @default.
- W4372203436 title "Dopaminergic and norepinephrinergic modulation of endogenous event-related potentials: A systematic review and meta-analysis" @default.
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