FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4372313268> ?p ?o ?g. }

• W4372313268 abstract "To develop and validate a predictive nomogram for tumor residue 3-6 months after treatment based on postradiotherapy plasma Epstein-Barr virus (EBV) deoxyribonucleic acid (DNA), clinical stage, and radiotherapy (RT) dose in patients with stage II-IVA nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiation therapy (IMRT).In this retrospective study, 1050 eligible patients with stage II-IVA NPC, who completed curative IMRT and underwent pretreatment and postradiotherapy (-7 to +28 days after IMRT) EBV DNA testing, were enrolled from 2012 to 2017. The prognostic value of the residue was explored using Cox regression analysis in patients (n=1050). A nomogram for predicting tumor residues after 3-6 months was developed using logistic regression analyses in the development cohort (n=736) and validated in an internal cohort (n=314).Tumor residue was an independent inferior prognostic factor for 5-year overall survival, progression-free survival, locoregional recurrence-free survival and distant metastasis-free survival (all P<0.001). A prediction nomogram based on postradiotherapy plasma EBV DNA level (0 vs. 1-499 vs. ≥500 copies/ml), clinical stage (II vs. III vs. IVA), and RT dose (68.00-69.96 vs. 70.00-74.00 Gy) estimated the probability of residue development. The nomogram showed better discrimination (area under the curve (AUC): 0.752) than either the clinical stage (0.659) or postradiotherapy EBV DNA level (0.627) alone in the development and validation cohorts (AUC: 0.728).We developed and validated a nomogram model integrating clinical characteristics at the end of IMRT for predicting whether tumor will residue or not after 3-6 months. Thus, high-risk NPC patients who might benefit from immediate additional intervention could be identified by the model, and the probability of residue can be reduced in the future." @default.
• W4372313268 created "2023-05-07" @default.
• W4372313268 creator A5008171524 @default.
• W4372313268 creator A5014823568 @default.
• W4372313268 creator A5025216680 @default.
• W4372313268 creator A5032181924 @default.
• W4372313268 creator A5037660489 @default.
• W4372313268 creator A5047215778 @default.
• W4372313268 creator A5048052584 @default.
• W4372313268 creator A5055665508 @default.
• W4372313268 creator A5063145199 @default.
• W4372313268 creator A5067778191 @default.
• W4372313268 creator A5070961992 @default.
• W4372313268 creator A5071215674 @default.
• W4372313268 creator A5081244781 @default.
• W4372313268 date "2023-05-06" @default.
• W4372313268 modified "2023-10-03" @default.
• W4372313268 title "Tumor residue in patients with stage II–IVA nasopharyngeal carcinoma who received intensity-modulated radiation therapy: development and validation of a prediction nomogram integrating postradiotherapy plasma Epstein–Barr virus deoxyribonucleic acid, clinical stage, and radiotherapy dose" @default.
• W4372313268 cites W1968017437 @default.
• W4372313268 cites W1994321029 @default.
• W4372313268 cites W2001333968 @default.
• W4372313268 cites W2001924074 @default.
• W4372313268 cites W2008267376 @default.
• W4372313268 cites W2031105319 @default.
• W4372313268 cites W2054504841 @default.
• W4372313268 cites W2072300649 @default.
• W4372313268 cites W2098802000 @default.
• W4372313268 cites W2105589623 @default.
• W4372313268 cites W2130492755 @default.
• W4372313268 cites W2131589968 @default.
• W4372313268 cites W2136080892 @default.
• W4372313268 cites W2138066012 @default.
• W4372313268 cites W2147380663 @default.
• W4372313268 cites W2148480080 @default.
• W4372313268 cites W2148754315 @default.
• W4372313268 cites W2149067175 @default.
• W4372313268 cites W2161986916 @default.
• W4372313268 cites W2174306046 @default.
• W4372313268 cites W2186378789 @default.
• W4372313268 cites W2328176404 @default.
• W4372313268 cites W2348566907 @default.
• W4372313268 cites W2567143849 @default.
• W4372313268 cites W2573152477 @default.
• W4372313268 cites W2592043832 @default.
• W4372313268 cites W2621704337 @default.
• W4372313268 cites W2802475838 @default.
• W4372313268 cites W2881137594 @default.
• W4372313268 cites W2947165726 @default.
• W4372313268 cites W2999142891 @default.
• W4372313268 cites W3012695695 @default.
• W4372313268 cites W3021836841 @default.
• W4372313268 cites W3090586523 @default.
• W4372313268 cites W3115988948 @default.
• W4372313268 cites W3118937854 @default.
• W4372313268 cites W3119658120 @default.
• W4372313268 cites W3172428308 @default.
• W4372313268 cites W3201249639 @default.
• W4372313268 cites W4211017340 @default.
• W4372313268 cites W4324009880 @default.
• W4372313268 doi "https://doi.org/10.1186/s12885-023-10827-0" @default.
• W4372313268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37149594" @default.
• W4372313268 hasPublicationYear "2023" @default.
• W4372313268 type Work @default.
• W4372313268 citedByCount "0" @default.
• W4372313268 crossrefType "journal-article" @default.
• W4372313268 hasAuthorship W4372313268A5008171524 @default.
• W4372313268 hasAuthorship W4372313268A5014823568 @default.
• W4372313268 hasAuthorship W4372313268A5025216680 @default.
• W4372313268 hasAuthorship W4372313268A5032181924 @default.
• W4372313268 hasAuthorship W4372313268A5037660489 @default.
• W4372313268 hasAuthorship W4372313268A5047215778 @default.
• W4372313268 hasAuthorship W4372313268A5048052584 @default.
• W4372313268 hasAuthorship W4372313268A5055665508 @default.
• W4372313268 hasAuthorship W4372313268A5063145199 @default.
• W4372313268 hasAuthorship W4372313268A5067778191 @default.
• W4372313268 hasAuthorship W4372313268A5070961992 @default.
• W4372313268 hasAuthorship W4372313268A5071215674 @default.
• W4372313268 hasAuthorship W4372313268A5081244781 @default.
• W4372313268 hasBestOaLocation W43723132681 @default.
• W4372313268 hasConcept C126322002 @default.
• W4372313268 hasConcept C143998085 @default.
• W4372313268 hasConcept C146357865 @default.
• W4372313268 hasConcept C151730666 @default.
• W4372313268 hasConcept C167135981 @default.
• W4372313268 hasConcept C2778997737 @default.
• W4372313268 hasConcept C2989005 @default.
• W4372313268 hasConcept C34626388 @default.
• W4372313268 hasConcept C50382708 @default.
• W4372313268 hasConcept C509974204 @default.
• W4372313268 hasConcept C71924100 @default.
• W4372313268 hasConcept C72563966 @default.
• W4372313268 hasConcept C86803240 @default.
• W4372313268 hasConcept C90924648 @default.
• W4372313268 hasConceptScore W4372313268C126322002 @default.
• W4372313268 hasConceptScore W4372313268C143998085 @default.
• W4372313268 hasConceptScore W4372313268C146357865 @default.
• W4372313268 hasConceptScore W4372313268C151730666 @default.
• W4372313268 hasConceptScore W4372313268C167135981 @default.
• W4372313268 hasConceptScore W4372313268C2778997737 @default.
• W4372313268 hasConceptScore W4372313268C2989005 @default.

• next