FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4372337657> ?p ?o ?g. }

• W4372337657 endingPage "194760352211186" @default.
• W4372337657 startingPage "194760352211186" @default.
• W4372337657 abstract "Vitrification of articular cartilage (AC) is a promising technique which may enable long-term tissue banking of AC allografts. We previously developed a 2-step, dual-temperature, multi-cryoprotectant agent (CPA) loading protocol to cryopreserve particulated AC (1 mm3 cubes). Furthermore, we also determined that the inclusion of ascorbic acid (AA) effectively mitigates CPA toxicity in cryopreserved AC. Prior to clinical translation, chondrocytes must remain viable after tissue re-warming and before transplantation. However, the effects of short-term hypothermic storage of particulated AC after vitrification and re-warming are not documented. This study evaluated the chondrocyte viability of post-vitrified particulated AC during a 7-day tissue storage period at 4 °C. We hypothesized that porcine particulated AC could be stored for up to 7 days after successful vitrification without significant loss of cell viability, and these results would be enhanced when cartilage is incubated in storage medium supplemented with clinical grade AA.Three experimental groups were examined at 5 time points: a fresh control (only incubated in medium), a vitrified - AA group, and a vitrified + AA group (N = 7).There was a mild decline in cell viability but both treatment groups maintained a viability of greater than 80% viable cells which is acceptable for clinical translation.We determined that particulated AC can be stored for up to 7 days after successful vitrification without a clinically significant decline in chondrocyte viability. This information can be used to guide tissue banks regarding the implementation of AC vitrification to increase cartilage allograft availability." @default.
• W4372337657 created "2023-05-07" @default.
• W4372337657 creator A5025426540 @default.
• W4372337657 creator A5026070633 @default.
• W4372337657 creator A5030470774 @default.
• W4372337657 creator A5036256954 @default.
• W4372337657 creator A5064512528 @default.
• W4372337657 creator A5070197790 @default.
• W4372337657 creator A5083851547 @default.
• W4372337657 date "2023-05-06" @default.
• W4372337657 modified "2023-09-26" @default.
• W4372337657 title "Chondrocyte Viability of Particulated Porcine Articular Cartilage Is Maintained in Tissue Storage After Cryoprotectant Exposure, Vitrification, and Tissue Warming" @default.
• W4372337657 cites W1498079026 @default.
• W4372337657 cites W1812173421 @default.
• W4372337657 cites W1894819560 @default.
• W4372337657 cites W1926917876 @default.
• W4372337657 cites W1967291580 @default.
• W4372337657 cites W1967477876 @default.
• W4372337657 cites W1989352925 @default.
• W4372337657 cites W1992671072 @default.
• W4372337657 cites W2009888584 @default.
• W4372337657 cites W2011038175 @default.
• W4372337657 cites W2012202237 @default.
• W4372337657 cites W2024447227 @default.
• W4372337657 cites W2028363445 @default.
• W4372337657 cites W2039849523 @default.
• W4372337657 cites W2070260162 @default.
• W4372337657 cites W2083810223 @default.
• W4372337657 cites W2091541550 @default.
• W4372337657 cites W2100872082 @default.
• W4372337657 cites W2116134385 @default.
• W4372337657 cites W2124636884 @default.
• W4372337657 cites W2154000401 @default.
• W4372337657 cites W2164351458 @default.
• W4372337657 cites W2168576724 @default.
• W4372337657 cites W2172990979 @default.
• W4372337657 cites W2173506395 @default.
• W4372337657 cites W2185509750 @default.
• W4372337657 cites W2195945456 @default.
• W4372337657 cites W2326146330 @default.
• W4372337657 cites W2342613583 @default.
• W4372337657 cites W2395856029 @default.
• W4372337657 cites W2587317072 @default.
• W4372337657 cites W2905826186 @default.
• W4372337657 cites W2918376130 @default.
• W4372337657 cites W2949658782 @default.
• W4372337657 cites W2991312984 @default.
• W4372337657 cites W2999715847 @default.
• W4372337657 cites W3046769973 @default.
• W4372337657 cites W3094146477 @default.
• W4372337657 cites W3109891627 @default.
• W4372337657 cites W3130154280 @default.
• W4372337657 cites W3136060904 @default.
• W4372337657 cites W3185499831 @default.
• W4372337657 cites W3206829594 @default.
• W4372337657 cites W4210951291 @default.
• W4372337657 cites W3048169521 @default.
• W4372337657 doi "https://doi.org/10.1177/19476035221118656" @default.
• W4372337657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37148124" @default.
• W4372337657 hasPublicationYear "2023" @default.
• W4372337657 type Work @default.
• W4372337657 citedByCount "0" @default.
• W4372337657 crossrefType "journal-article" @default.
• W4372337657 hasAuthorship W4372337657A5025426540 @default.
• W4372337657 hasAuthorship W4372337657A5026070633 @default.
• W4372337657 hasAuthorship W4372337657A5030470774 @default.
• W4372337657 hasAuthorship W4372337657A5036256954 @default.
• W4372337657 hasAuthorship W4372337657A5064512528 @default.
• W4372337657 hasAuthorship W4372337657A5070197790 @default.
• W4372337657 hasAuthorship W4372337657A5083851547 @default.
• W4372337657 hasBestOaLocation W43723376571 @default.
• W4372337657 hasConcept C105702510 @default.
• W4372337657 hasConcept C141071460 @default.
• W4372337657 hasConcept C1491633281 @default.
• W4372337657 hasConcept C16685009 @default.
• W4372337657 hasConcept C179933525 @default.
• W4372337657 hasConcept C185592680 @default.
• W4372337657 hasConcept C196843134 @default.
• W4372337657 hasConcept C2778022349 @default.
• W4372337657 hasConcept C2780550940 @default.
• W4372337657 hasConcept C2781403057 @default.
• W4372337657 hasConcept C2911091166 @default.
• W4372337657 hasConcept C53227056 @default.
• W4372337657 hasConcept C55493867 @default.
• W4372337657 hasConcept C68528507 @default.
• W4372337657 hasConcept C71924100 @default.
• W4372337657 hasConcept C86803240 @default.
• W4372337657 hasConcept C95444343 @default.
• W4372337657 hasConceptScore W4372337657C105702510 @default.
• W4372337657 hasConceptScore W4372337657C141071460 @default.
• W4372337657 hasConceptScore W4372337657C1491633281 @default.
• W4372337657 hasConceptScore W4372337657C16685009 @default.
• W4372337657 hasConceptScore W4372337657C179933525 @default.
• W4372337657 hasConceptScore W4372337657C185592680 @default.
• W4372337657 hasConceptScore W4372337657C196843134 @default.
• W4372337657 hasConceptScore W4372337657C2778022349 @default.
• W4372337657 hasConceptScore W4372337657C2780550940 @default.
• W4372337657 hasConceptScore W4372337657C2781403057 @default.

• next