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- W4375844553 abstract "Abstract: Quinoline and its derivatives have been utilized and marketed as antibacterial, antimalarial, anticancer, hypertension, asthma (COPD), etc. The diverse pharmacological properties of quinolone are related to its chemical structure. Nowadays, it is common practice to combine at least two pharmacophores to create a single molecule with powerful pharmacological effects. This helps to synergize pharmacological qualities, enables interaction with several targets, or lessens the negative effects related to them. Various synthetic approaches which have been used in recent times for the synthesis of quinoline and its derivatives are listed in the manuscript with their merits and demerit. The structure-activity relationship relating various pharmacological actions with molecular structure and interaction with several targets has also been highlighted to provide a good comprehension to the researchers for future studies on quinoline." @default.
- W4375844553 created "2023-05-10" @default.
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- W4375844553 date "2023-05-05" @default.
- W4375844553 modified "2023-09-23" @default.
- W4375844553 title "Quinoline and Analogs: Insight into the synthesis, biological activity, structure-activity relationship, and interaction with targets" @default.
- W4375844553 doi "https://doi.org/10.2174/1570193x20666230505152611" @default.
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