Matches in SemOpenAlex for { <https://semopenalex.org/work/W4375846976> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W4375846976 endingPage "5739" @default.
- W4375846976 startingPage "5736" @default.
- W4375846976 abstract "High genetic variability of the hepatitis C virus (HCV) due to copying errors during the viral cycle leads to the development of mutations, and resistance-associated variants (RAVs), even with the advent of direct-acting antivirals (DAAs). Assessment of the presence of these mutations is essential for targeted treatment regimens and proper infection management, as treatment is related to genotypes and developing mutations. The study investigates the presence of resistance mutations in the nonstructural protein 5B (NS5B) region in treatment naïve patients. 100 positive plasma samples from patients presented for a follow-up service of chronic HCV infection (CHC) at the National Institute of Hygiene (NIH) of Rabat-Morocco. NS5B sequencing revealed the presence of C316N in one treatment naïve patient of subtype 1b. Additionally, six treatment-naïve patients with subtypes 2a and 2i exhibited the presence of the M289L mutation." @default.
- W4375846976 created "2023-05-10" @default.
- W4375846976 creator A5092335982 @default.
- W4375846976 date "2023-04-30" @default.
- W4375846976 modified "2023-09-30" @default.
- W4375846976 title "C316N Polymorphism associated with resistance to HCV polymerase NS5B in treatment-naïve patient with chronic hepatitis C" @default.
- W4375846976 doi "https://doi.org/10.55522/jmpas.v12i2.4763" @default.
- W4375846976 hasPublicationYear "2023" @default.
- W4375846976 type Work @default.
- W4375846976 citedByCount "0" @default.
- W4375846976 crossrefType "journal-article" @default.
- W4375846976 hasAuthorship W4375846976A5092335982 @default.
- W4375846976 hasBestOaLocation W43758469761 @default.
- W4375846976 hasConcept C104317684 @default.
- W4375846976 hasConcept C135763542 @default.
- W4375846976 hasConcept C156719811 @default.
- W4375846976 hasConcept C159047783 @default.
- W4375846976 hasConcept C182707283 @default.
- W4375846976 hasConcept C203014093 @default.
- W4375846976 hasConcept C2522874641 @default.
- W4375846976 hasConcept C2776408679 @default.
- W4375846976 hasConcept C2781426373 @default.
- W4375846976 hasConcept C2781463415 @default.
- W4375846976 hasConcept C3020491458 @default.
- W4375846976 hasConcept C49105822 @default.
- W4375846976 hasConcept C501734568 @default.
- W4375846976 hasConcept C54355233 @default.
- W4375846976 hasConcept C71924100 @default.
- W4375846976 hasConcept C86803240 @default.
- W4375846976 hasConceptScore W4375846976C104317684 @default.
- W4375846976 hasConceptScore W4375846976C135763542 @default.
- W4375846976 hasConceptScore W4375846976C156719811 @default.
- W4375846976 hasConceptScore W4375846976C159047783 @default.
- W4375846976 hasConceptScore W4375846976C182707283 @default.
- W4375846976 hasConceptScore W4375846976C203014093 @default.
- W4375846976 hasConceptScore W4375846976C2522874641 @default.
- W4375846976 hasConceptScore W4375846976C2776408679 @default.
- W4375846976 hasConceptScore W4375846976C2781426373 @default.
- W4375846976 hasConceptScore W4375846976C2781463415 @default.
- W4375846976 hasConceptScore W4375846976C3020491458 @default.
- W4375846976 hasConceptScore W4375846976C49105822 @default.
- W4375846976 hasConceptScore W4375846976C501734568 @default.
- W4375846976 hasConceptScore W4375846976C54355233 @default.
- W4375846976 hasConceptScore W4375846976C71924100 @default.
- W4375846976 hasConceptScore W4375846976C86803240 @default.
- W4375846976 hasIssue "2" @default.
- W4375846976 hasLocation W43758469761 @default.
- W4375846976 hasOpenAccess W4375846976 @default.
- W4375846976 hasPrimaryLocation W43758469761 @default.
- W4375846976 hasRelatedWork W1988825091 @default.
- W4375846976 hasRelatedWork W2008024230 @default.
- W4375846976 hasRelatedWork W2034793309 @default.
- W4375846976 hasRelatedWork W2040778513 @default.
- W4375846976 hasRelatedWork W2078169456 @default.
- W4375846976 hasRelatedWork W2118565957 @default.
- W4375846976 hasRelatedWork W2306533667 @default.
- W4375846976 hasRelatedWork W2472129033 @default.
- W4375846976 hasRelatedWork W2953494464 @default.
- W4375846976 hasRelatedWork W4289517873 @default.
- W4375846976 hasVolume "12" @default.
- W4375846976 isParatext "false" @default.
- W4375846976 isRetracted "false" @default.
- W4375846976 workType "article" @default.