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- W4375851627 abstract "Energy is needed by cancer cells to stay alive and communicate with their surroundings. The primary organelles for cellular metabolism and energy synthesis are mitochondria. Researchers recently proved that cancer cells can steal immune cells' mitochondria using nanoscale tubes. This finding demonstrates the dependence of cancer cells on normal cells for their living and function. It also denotes the importance of mitochondria in cancer cells’ biology. Emerging evidence has demonstrated how mitochondria are essential for cancer cells to survive in the harsh tumor microenvironment, evade the immune system, obtain more aggressive features, and resist treatments. For instance, functional mitochondria can improve cancer resistance against radiotherapy by scavenging the released reactive oxygen species. Therefore, targeting mitochondria can potentially enhance oncological outcomes, according to this notion. The patients' reactions to radiation are varied, ranging from a complete response to even cancer progression during treatment. This concept illustrates how different levels of mitochondrial metabolism might contribute to this heterogeneity. Considering this notion can help to improve personalized oncological treatments. This article outlines the importance of mitochondrial metabolism in cancer biology and personalized treatments." @default.
- W4375851627 created "2023-05-10" @default.
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- W4375851627 date "2023-05-08" @default.
- W4375851627 modified "2023-09-29" @default.
- W4375851627 title "Anti-mitochondrial Therapy: A New Dimension of Personalized Oncology" @default.
- W4375851627 doi "https://doi.org/10.20944/preprints202305.0482.v1" @default.
- W4375851627 hasPublicationYear "2023" @default.
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