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- W4375852223 abstract "We thank Chambal et al. 1 Chambal M, Forsthoffer C, Egnaczyk A, et. al. Comparison of Targeted vs. expanded pharmacogenomic testing: what are we missing? J Am Pharm Assoc (2003), in press. Google Scholar for publishing “Comparison of targeted vs. expanded pharmacogenomic testing: What are we missing?” As clinicians who offer pharmacogenomics (PGx) services, we believe that the greatest benefit of expanded PGx testing is within primary care. 2 Massart M. Berenbrok L.A. Munro C. Berman N.R. Empey P.E. A multidisciplinary precision medicine service in primary care. Ann Fam Med. 2022; 20: 88 Crossref Scopus (0) Google Scholar Currently, our multidisciplinary primary care team uses multigene PGx panels that include gene-drug pairs with and without Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines and PGx data in Food and Drug Administration medication labeling. 3 Guidelines. Clinical Pharmacogenetics Implementation Consortium. https://cpicpgx.org/guidelines/Date accessed: April 26, 2023 Google Scholar ,4 Table of pharmacogenomic biomarkers in drug labeling. U.S. Food & Drug Administration. https://www.fda.gov/drugs/science-and-research-drugs/table-pharmacogenomic-biomarkers-drug-labelingDate accessed: April 26, 2023 Google Scholar Although we do not interpret pharmacogenes with low evidence supporting a gene-drug interaction, we believe that primary care teams are well positioned to maximize the utility of expanded PGx panels by interpreting genes with CPIC guidelines and reinterpreting results as evidence for gene-drug pairs strengthen. Furthermore, when expanded PGx testing panels are ordered by primary care teams, we believe that the data can be comprehensively documented to avoid costs associated with ordering multiple PGx tests over a patient’s lifetime." @default.
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- W4375852223 date "2023-05-01" @default.
- W4375852223 modified "2023-09-26" @default.
- W4375852223 title "Primary care is what’s missing: A response to a comparison of targeted vs. expanded pharmacogenomic testing" @default.
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- W4375852223 doi "https://doi.org/10.1016/j.japh.2023.05.004" @default.
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