FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4375855765> ?p ?o ?g. }

• W4375855765 endingPage "948" @default.
• W4375855765 startingPage "937" @default.
• W4375855765 abstract "Abstract Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at an unprecedented temporal precision for neurological disorders. This has the potential to lead to a breakthrough in neurotechnology, but the translation to clinical practice remains a significant challenge. Via bidirectional implantable brain‐computer‐interfaces that have become commercially available, aDBS can now sense and selectively modulate pathophysiological brain circuit activity. Pilot studies investigating different aDBS control strategies showed promising results, but the short experimental study designs have not yet supported individualized analyses of patient‐specific factors in biomarker and therapeutic response dynamics. Notwithstanding the clear theoretical advantages of a patient‐tailored approach, these new stimulation possibilities open a vast and mostly unexplored parameter space, leading to practical hurdles in the implementation and development of clinical trials. Therefore, a thorough understanding of the neurophysiological and neurotechnological aspects related to aDBS is crucial to develop evidence‐based treatment regimens for clinical practice. Therapeutic success of aDBS will depend on the integrated development of strategies for feedback signal identification, artifact mitigation, signal processing, and control policy adjustment, for precise stimulation delivery tailored to individual patients. The present review introduces the reader to the neurophysiological foundation of aDBS for Parkinson's disease (PD) and other network disorders, explains currently available aDBS control policies, and highlights practical pitfalls and difficulties to be addressed in the upcoming years. Finally, it highlights the importance of interdisciplinary clinical neurotechnological research within and across DBS centers, toward an individualized patient‐centered approach to invasive brain stimulation. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society." @default.
• W4375855765 created "2023-05-10" @default.
• W4375855765 creator A5004124787 @default.
• W4375855765 creator A5039521481 @default.
• W4375855765 creator A5058848174 @default.
• W4375855765 creator A5067475369 @default.
• W4375855765 date "2023-05-06" @default.
• W4375855765 modified "2023-10-03" @default.
• W4375855765 title "Adaptive Deep Brain Stimulation: From Experimental Evidence Toward Practical Implementation" @default.
• W4375855765 cites W1498617277 @default.
• W4375855765 cites W1554611386 @default.
• W4375855765 cites W1624016815 @default.
• W4375855765 cites W1911165778 @default.
• W4375855765 cites W1967168287 @default.
• W4375855765 cites W2048658576 @default.
• W4375855765 cites W2056777881 @default.
• W4375855765 cites W2087550316 @default.
• W4375855765 cites W2098219093 @default.
• W4375855765 cites W2103908673 @default.
• W4375855765 cites W2124211545 @default.
• W4375855765 cites W2131981265 @default.
• W4375855765 cites W2141405085 @default.
• W4375855765 cites W2143685192 @default.
• W4375855765 cites W2310916568 @default.
• W4375855765 cites W2423154567 @default.
• W4375855765 cites W2511969663 @default.
• W4375855765 cites W2515990420 @default.
• W4375855765 cites W2556228493 @default.
• W4375855765 cites W2559957586 @default.
• W4375855765 cites W2588429935 @default.
• W4375855765 cites W2599888381 @default.
• W4375855765 cites W2682270125 @default.
• W4375855765 cites W2742778017 @default.
• W4375855765 cites W2744169335 @default.
• W4375855765 cites W2759599347 @default.
• W4375855765 cites W2764335780 @default.
• W4375855765 cites W2768053978 @default.
• W4375855765 cites W2778986485 @default.
• W4375855765 cites W2786828489 @default.
• W4375855765 cites W2792770438 @default.
• W4375855765 cites W2802450380 @default.
• W4375855765 cites W2808855215 @default.
• W4375855765 cites W2885369490 @default.
• W4375855765 cites W2885584851 @default.
• W4375855765 cites W2885729211 @default.
• W4375855765 cites W2890333253 @default.
• W4375855765 cites W2899579807 @default.
• W4375855765 cites W2900501779 @default.
• W4375855765 cites W2907666668 @default.
• W4375855765 cites W2917762754 @default.
• W4375855765 cites W2920832879 @default.
• W4375855765 cites W2927340161 @default.
• W4375855765 cites W2954375104 @default.
• W4375855765 cites W2971601388 @default.
• W4375855765 cites W2990929233 @default.
• W4375855765 cites W2998787804 @default.
• W4375855765 cites W3005992334 @default.
• W4375855765 cites W3006227044 @default.
• W4375855765 cites W3026423714 @default.
• W4375855765 cites W3042523037 @default.
• W4375855765 cites W3045835085 @default.
• W4375855765 cites W3092364559 @default.
• W4375855765 cites W3097021208 @default.
• W4375855765 cites W3108898910 @default.
• W4375855765 cites W3111484088 @default.
• W4375855765 cites W3128863783 @default.
• W4375855765 cites W3133918036 @default.
• W4375855765 cites W3154587456 @default.
• W4375855765 cites W3158340479 @default.
• W4375855765 cites W3161936698 @default.
• W4375855765 cites W3180762017 @default.
• W4375855765 cites W3185943518 @default.
• W4375855765 cites W3193363096 @default.
• W4375855765 cites W3194613969 @default.
• W4375855765 cites W3204511428 @default.
• W4375855765 cites W3206442043 @default.
• W4375855765 cites W3208276566 @default.
• W4375855765 cites W3209518402 @default.
• W4375855765 cites W3214055161 @default.
• W4375855765 cites W4200465000 @default.
• W4375855765 cites W4210458691 @default.
• W4375855765 cites W4213435970 @default.
• W4375855765 cites W4214936523 @default.
• W4375855765 cites W4220745162 @default.
• W4375855765 cites W4220787531 @default.
• W4375855765 cites W4224245946 @default.
• W4375855765 cites W4248105862 @default.
• W4375855765 cites W4281867964 @default.
• W4375855765 cites W4284893694 @default.
• W4375855765 cites W4318615238 @default.
• W4375855765 doi "https://doi.org/10.1002/mds.29415" @default.
• W4375855765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37148553" @default.
• W4375855765 hasPublicationYear "2023" @default.
• W4375855765 type Work @default.
• W4375855765 citedByCount "5" @default.
• W4375855765 countsByYear W43758557652023 @default.
• W4375855765 crossrefType "journal-article" @default.
• W4375855765 hasAuthorship W4375855765A5004124787 @default.

• next