Matches in SemOpenAlex for { <https://semopenalex.org/work/W4375862010> ?p ?o ?g. }
- W4375862010 endingPage "245" @default.
- W4375862010 startingPage "245" @default.
- W4375862010 abstract "Golden pompano, Trachinotus ovatus, is a perciform fish with great economic value and is widely cultured in the coastal areas of China. The wide occurrence of bacterial, parasitic and viral diseases has seriously threatened the sustainable development of the golden pompano culture industry. Janus kinases (JAKs) play important roles in most cytokine-mediated inflammatory responses, antiviral immune responses, autoimmune responses and disease pathologies. The present study aimed to obtain the full-length cDNA sequences of JAKs (JAK1, JAK2a, JAK3 and TYK2) from golden pompano and investigate their roles following stimulation with lipopolysaccharide (LPS), polyriboinosinic-polyribocytidylic acid (poly I:C) and Vibrio alginolyticus using RT-PCR, RACE-PCR and real-time qPCR methods. All four JAK proteins of golden pompano shared similar conserved domains, had high identities and clustered well with their teleost counterparts in phylogenetic analysis. Furthermore, these four genes were expressed in all examined tissues from healthy fish and induced in head kidney (HK), spleen, liver and gill post LPS, poly I:C and V. alginolyticus stimulation. Knowledge of the roles of JAKs in the immune response to different microbial pathogens provides a basis for further understanding of these functions." @default.
- W4375862010 created "2023-05-10" @default.
- W4375862010 creator A5010642062 @default.
- W4375862010 creator A5035969605 @default.
- W4375862010 creator A5045907811 @default.
- W4375862010 creator A5051629835 @default.
- W4375862010 creator A5053703803 @default.
- W4375862010 creator A5073817022 @default.
- W4375862010 creator A5087957402 @default.
- W4375862010 date "2023-05-08" @default.
- W4375862010 modified "2023-10-01" @default.
- W4375862010 title "Molecular Characterization and Expression Analysis of Four Janus Kinases (JAK1, JAK2a, JAK3 and TYK2) from Golden Pompano (Trachinotus ovatus)" @default.
- W4375862010 cites W1615372886 @default.
- W4375862010 cites W1671779243 @default.
- W4375862010 cites W1965295046 @default.
- W4375862010 cites W1966833202 @default.
- W4375862010 cites W1970308473 @default.
- W4375862010 cites W1978214927 @default.
- W4375862010 cites W1988473775 @default.
- W4375862010 cites W2004993813 @default.
- W4375862010 cites W2011438792 @default.
- W4375862010 cites W2040089362 @default.
- W4375862010 cites W2055339871 @default.
- W4375862010 cites W2083004364 @default.
- W4375862010 cites W2086941795 @default.
- W4375862010 cites W2107277218 @default.
- W4375862010 cites W2114065448 @default.
- W4375862010 cites W2173626692 @default.
- W4375862010 cites W2208388066 @default.
- W4375862010 cites W2311203695 @default.
- W4375862010 cites W2465710624 @default.
- W4375862010 cites W2508728094 @default.
- W4375862010 cites W2533540049 @default.
- W4375862010 cites W2548497570 @default.
- W4375862010 cites W2580811839 @default.
- W4375862010 cites W2601742683 @default.
- W4375862010 cites W2606815536 @default.
- W4375862010 cites W2765679226 @default.
- W4375862010 cites W2777659524 @default.
- W4375862010 cites W2781877560 @default.
- W4375862010 cites W2782957893 @default.
- W4375862010 cites W2805465930 @default.
- W4375862010 cites W2892635078 @default.
- W4375862010 cites W2892785178 @default.
- W4375862010 cites W2965910386 @default.
- W4375862010 cites W2968711795 @default.
- W4375862010 cites W2971188351 @default.
- W4375862010 cites W2995159094 @default.
- W4375862010 cites W3014462878 @default.
- W4375862010 cites W3037233470 @default.
- W4375862010 cites W3109694774 @default.
- W4375862010 cites W3109914560 @default.
- W4375862010 cites W3118519502 @default.
- W4375862010 cites W3157332822 @default.
- W4375862010 cites W3195237214 @default.
- W4375862010 cites W3202722940 @default.
- W4375862010 cites W3206298898 @default.
- W4375862010 cites W3215726358 @default.
- W4375862010 cites W4220836928 @default.
- W4375862010 cites W4221050240 @default.
- W4375862010 cites W4225133150 @default.
- W4375862010 cites W4229377733 @default.
- W4375862010 cites W4280610936 @default.
- W4375862010 cites W4283703910 @default.
- W4375862010 cites W4285730425 @default.
- W4375862010 cites W4285740773 @default.
- W4375862010 cites W4289014005 @default.
- W4375862010 cites W4292860322 @default.
- W4375862010 cites W4294946083 @default.
- W4375862010 cites W4297201355 @default.
- W4375862010 cites W4310136315 @default.
- W4375862010 cites W4313327488 @default.
- W4375862010 cites W4313530305 @default.
- W4375862010 cites W4313730610 @default.
- W4375862010 cites W4315853551 @default.
- W4375862010 cites W4317906732 @default.
- W4375862010 cites W4318483235 @default.
- W4375862010 cites W4319222348 @default.
- W4375862010 cites W4321487561 @default.
- W4375862010 cites W4321769001 @default.
- W4375862010 cites W4321793519 @default.
- W4375862010 doi "https://doi.org/10.3390/fishes8050245" @default.
- W4375862010 hasPublicationYear "2023" @default.
- W4375862010 type Work @default.
- W4375862010 citedByCount "0" @default.
- W4375862010 crossrefType "journal-article" @default.
- W4375862010 hasAuthorship W4375862010A5010642062 @default.
- W4375862010 hasAuthorship W4375862010A5035969605 @default.
- W4375862010 hasAuthorship W4375862010A5045907811 @default.
- W4375862010 hasAuthorship W4375862010A5051629835 @default.
- W4375862010 hasAuthorship W4375862010A5053703803 @default.
- W4375862010 hasAuthorship W4375862010A5073817022 @default.
- W4375862010 hasAuthorship W4375862010A5087957402 @default.
- W4375862010 hasBestOaLocation W43758620101 @default.
- W4375862010 hasConcept C104317684 @default.
- W4375862010 hasConcept C112392421 @default.
- W4375862010 hasConcept C136449434 @default.
- W4375862010 hasConcept C159047783 @default.