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- W4375865636 abstract "La scintigraphie osseuse est un examen d’imagerie nucléaire utilisant un radiopharmaceutique composé d’un biphosphonate couplé à un isotopie radioactif (technétium 99m). La fixation du radiopharmaceutique est particulièrement importante au niveau des structures osseuses ayant une forte activité ostéoblastique. Ces anomalies peuvent être secondaires à une pathologie bénigne (fracture, descellement de prothèse, pathologies rhumatismales, etc…) ou à une pathologie maligne (lésion primitive osseuse ou secondaire). Sa sensibilité élevée la rend particulièrement intéressante au stade initial de la pathologie, notamment quand les radiographies sont normales. Par ailleurs, la spécificité de la scintigraphie osseuse s’est nettement améliorée ces dernières années par l’utilisation de plus en plus fréquente de la tomographie couplée au scanner X. Nous détaillons le principe de fonctionnement de la scintigraphie osseuse, les fixations normales avec ses variantes ainsi que les fixations pathologiques dans les pathologies traumatiques, rhumatismales, prothétiques ou cancéreuses. Bone scintigraphy is a nuclear imaging scan using a radiopharmaceutical composed of a bisphosphonate coupled to a radionuclide (technetium 99m). Radiopharmaceutical uptake is particularly important at the level of the bone structures having a strong osteoblastic activity. These uptakes can be due to a benign pathology (fracture, loosening of prosthesis, rheumatic pathologies, etc.) or to a malignant pathology (primary or secondary bone lesion). The high sensitivity of bone scintigraphy makes it particularly interesting at the initial stage of the pathology, especially when X-rays are normal. In addition, its specificity has clearly improved in recent years with the increasingly use of tomoscintigraphy coupled with X-ray scanning (SPECT/CT). We describe the operating principle of bone scintigraphy, normal uptakes with its variants as well as pathological uptake features in traumatic, rheumatic, prosthetic or cancerous pathologies." @default.
- W4375865636 created "2023-05-10" @default.
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- W4375865636 date "2023-05-01" @default.
- W4375865636 modified "2023-10-17" @default.
- W4375865636 title "Partie 7. Spécificités pédiatriques" @default.
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- W4375865636 doi "https://doi.org/10.1016/j.mednuc.2023.03.009" @default.
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