FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4375956051> ?p ?o ?g. }

• W4375956051 abstract "Abstract Background and Aims Colectomy and reconstruction in patients with inflammatory bowel disease [IBD] may adversely affect fertility, but few population-based studies on this subject are available. Methods Fertility was assessed in 2989 women and 3771 men with IBD and prior colectomy during 1964–2014, identified from the Swedish National Patient Register, and in 35 092 matched individuals. Results Reconstruction with ileoanal pouch anastomosis [IPAA] was as common as ileorectal anastomosis [IRA] in ulcerative colitis [UC] and IBD-unclassified [IBD-U] but rare in Crohn’s disease [CD]. Compared with the matched reference cohort, women with IBD had lower fertility overall after colectomy (hazard ratio [HR] 0.65, confidence interval [CI] 0.61–0.69), with least impact with leaving the rectum intact [HR 0.79, CI 0.70–0.90]. Compared with colectomy only, fertility in female patients remained unaffected after IRA [HR 0.86, CI 0.63–1.17 for UC, 0.86, CI 0.68–1.08 for IBD-U and 1.07, CI 0.70–1.63 for CD], but was impaired after IPAA, especially in UC [HR 0.67, CI 0.50–0.88], and after completion proctectomy [HR 0.65, CI 0.49–0.85 for UC, 0.68, CI 0.55–0.85 for IBD-U and 0.61, CI 0.38–0.96 for CD]. In men, fertility was marginally reduced following colectomy [HR 0.89, CI 0.85–0.94], regardless of reconstruction. Conclusions Fertility was reduced in women after colectomy for IBD. The least impact was seen when a deviated rectum was left intact. IRA was associated with no further reduction in fertility, whereas proctectomy and IPAA were associated with the strongest impairment. IRA therefore seems to be the preferred reconstruction to preserve fertility in selected female patients. Fertility in men was only moderately reduced after colectomy." @default.
• W4375956051 created "2023-05-10" @default.
• W4375956051 creator A5022647341 @default.
• W4375956051 creator A5038901877 @default.
• W4375956051 creator A5046569826 @default.
• W4375956051 creator A5058647879 @default.
• W4375956051 date "2023-05-09" @default.
• W4375956051 modified "2023-10-01" @default.
• W4375956051 title "Female and Male Fertility after Colectomy and Reconstructive Surgery in Inflammatory Bowel Diesase: A National Cohort Study from Sweden" @default.
• W4375956051 cites W144464069 @default.
• W4375956051 cites W1825250834 @default.
• W4375956051 cites W1997654936 @default.
• W4375956051 cites W2022373216 @default.
• W4375956051 cites W2026706338 @default.
• W4375956051 cites W2040454131 @default.
• W4375956051 cites W2044879509 @default.
• W4375956051 cites W2059673635 @default.
• W4375956051 cites W2141761576 @default.
• W4375956051 cites W2149347585 @default.
• W4375956051 cites W2149880732 @default.
• W4375956051 cites W2164180626 @default.
• W4375956051 cites W2166018731 @default.
• W4375956051 cites W2166946715 @default.
• W4375956051 cites W2185850265 @default.
• W4375956051 cites W2188248802 @default.
• W4375956051 cites W2233885014 @default.
• W4375956051 cites W2279883728 @default.
• W4375956051 cites W2299180075 @default.
• W4375956051 cites W2330307193 @default.
• W4375956051 cites W2546063853 @default.
• W4375956051 cites W2563421175 @default.
• W4375956051 cites W2578653911 @default.
• W4375956051 cites W2589398327 @default.
• W4375956051 cites W2611154315 @default.
• W4375956051 cites W2921768776 @default.
• W4375956051 cites W2988977315 @default.
• W4375956051 cites W3087428338 @default.
• W4375956051 cites W4281286337 @default.
• W4375956051 cites W4285590073 @default.
• W4375956051 cites W4323284210 @default.
• W4375956051 cites W959798553 @default.
• W4375956051 doi "https://doi.org/10.1093/ecco-jcc/jjad079" @default.
• W4375956051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37158789" @default.
• W4375956051 hasPublicationYear "2023" @default.
• W4375956051 type Work @default.
• W4375956051 citedByCount "0" @default.
• W4375956051 crossrefType "journal-article" @default.
• W4375956051 hasAuthorship W4375956051A5022647341 @default.
• W4375956051 hasAuthorship W4375956051A5038901877 @default.
• W4375956051 hasAuthorship W4375956051A5046569826 @default.
• W4375956051 hasAuthorship W4375956051A5058647879 @default.
• W4375956051 hasBestOaLocation W43759560511 @default.
• W4375956051 hasConcept C126322002 @default.
• W4375956051 hasConcept C141071460 @default.
• W4375956051 hasConcept C207103383 @default.
• W4375956051 hasConcept C2776667177 @default.
• W4375956051 hasConcept C2777077811 @default.
• W4375956051 hasConcept C2778260677 @default.
• W4375956051 hasConcept C2779134260 @default.
• W4375956051 hasConcept C2780479503 @default.
• W4375956051 hasConcept C2781074409 @default.
• W4375956051 hasConcept C2908647359 @default.
• W4375956051 hasConcept C29456083 @default.
• W4375956051 hasConcept C44249647 @default.
• W4375956051 hasConcept C518429986 @default.
• W4375956051 hasConcept C71924100 @default.
• W4375956051 hasConcept C72563966 @default.
• W4375956051 hasConcept C90924648 @default.
• W4375956051 hasConcept C99454951 @default.
• W4375956051 hasConceptScore W4375956051C126322002 @default.
• W4375956051 hasConceptScore W4375956051C141071460 @default.
• W4375956051 hasConceptScore W4375956051C207103383 @default.
• W4375956051 hasConceptScore W4375956051C2776667177 @default.
• W4375956051 hasConceptScore W4375956051C2777077811 @default.
• W4375956051 hasConceptScore W4375956051C2778260677 @default.
• W4375956051 hasConceptScore W4375956051C2779134260 @default.
• W4375956051 hasConceptScore W4375956051C2780479503 @default.
• W4375956051 hasConceptScore W4375956051C2781074409 @default.
• W4375956051 hasConceptScore W4375956051C2908647359 @default.
• W4375956051 hasConceptScore W4375956051C29456083 @default.
• W4375956051 hasConceptScore W4375956051C44249647 @default.
• W4375956051 hasConceptScore W4375956051C518429986 @default.
• W4375956051 hasConceptScore W4375956051C71924100 @default.
• W4375956051 hasConceptScore W4375956051C72563966 @default.
• W4375956051 hasConceptScore W4375956051C90924648 @default.
• W4375956051 hasConceptScore W4375956051C99454951 @default.
• W4375956051 hasLocation W43759560511 @default.
• W4375956051 hasLocation W43759560512 @default.
• W4375956051 hasOpenAccess W4375956051 @default.
• W4375956051 hasPrimaryLocation W43759560511 @default.
• W4375956051 hasRelatedWork W1600938591 @default.
• W4375956051 hasRelatedWork W1998231725 @default.
• W4375956051 hasRelatedWork W2031512696 @default.
• W4375956051 hasRelatedWork W2063017601 @default.
• W4375956051 hasRelatedWork W2065075660 @default.
• W4375956051 hasRelatedWork W2073501359 @default.
• W4375956051 hasRelatedWork W207598912 @default.
• W4375956051 hasRelatedWork W2312951914 @default.
• W4375956051 hasRelatedWork W2784614229 @default.
• W4375956051 hasRelatedWork W4254196334 @default.

• next