FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376105364> ?p ?o ?g. }

• W4376105364 endingPage "7776" @default.
• W4376105364 startingPage "7765" @default.
• W4376105364 abstract "Lycopene β-cyclase (EC 5.5.1.19) is one of the key enzymes in the biosynthesis of β-carotene and derived carotenoids. It catalyzes isomerase reactions to form β-carotene from lycopene by β-cyclization of both of its ψ-ends. Lycopene β-cyclases are widespread in nature. We systematically analyzed the phylogeny of lycopene β-cyclases from all kingdoms of life and predicted their transmembrane structures. To this end, a collection of previously characterized lycopene β-cyclase polypeptide sequences served as bait sequences to identify their closest homologues in a range of bacteria, archaea, fungi, algae, and plant species. Furthermore, a DeepTMHMM scan was applied to search for the presence of transmembrane domains. A phylogenetic tree suggests at least five distinct clades, and the DeepTMHMM scan revealed that lycopene β-cyclases are a group of structurally different proteins: membrane-bound and cytosolic enzymes. Representative lycopene β-cyclases were screened in the lycopene-overproducing Corynebacterium glutamicum strain for β-carotene and astaxanthin production. This systematic screening facilitates the identification of new enzymes for carotenoid production. Higher astaxanthin production and less reduction of total carotenoids were achieved with the cytosolic lycopene β-cyclase CrtL from Synechococcus elongatus and the membrane-bound heterodimeric lycopene β-cyclase CrtYcd from Brevibacterium linens." @default.
• W4376105364 created "2023-05-12" @default.
• W4376105364 creator A5044478520 @default.
• W4376105364 creator A5053117100 @default.
• W4376105364 creator A5091393671 @default.
• W4376105364 creator A5091546829 @default.
• W4376105364 date "2023-05-10" @default.
• W4376105364 modified "2023-10-17" @default.
• W4376105364 title "Screening of Structurally Distinct Lycopene β-Cyclases for Production of the Cyclic C40 Carotenoids β-Carotene and Astaxanthin by <i>Corynebacterium glutamicum</i>" @default.
• W4376105364 cites W1880932991 @default.
• W4376105364 cites W1974833847 @default.
• W4376105364 cites W1977261325 @default.
• W4376105364 cites W1989201395 @default.
• W4376105364 cites W2020942708 @default.
• W4376105364 cites W2025770311 @default.
• W4376105364 cites W2028201207 @default.
• W4376105364 cites W2046858329 @default.
• W4376105364 cites W2049757216 @default.
• W4376105364 cites W2050648523 @default.
• W4376105364 cites W2055043387 @default.
• W4376105364 cites W2060814382 @default.
• W4376105364 cites W2066895678 @default.
• W4376105364 cites W2069573895 @default.
• W4376105364 cites W2079056573 @default.
• W4376105364 cites W2090892535 @default.
• W4376105364 cites W2111647009 @default.
• W4376105364 cites W2124762986 @default.
• W4376105364 cites W2151630859 @default.
• W4376105364 cites W2163860072 @default.
• W4376105364 cites W2164028644 @default.
• W4376105364 cites W2164136241 @default.
• W4376105364 cites W2164190876 @default.
• W4376105364 cites W2460756007 @default.
• W4376105364 cites W2603783018 @default.
• W4376105364 cites W2799414564 @default.
• W4376105364 cites W2799538853 @default.
• W4376105364 cites W2886079965 @default.
• W4376105364 cites W2982551297 @default.
• W4376105364 cites W3008999672 @default.
• W4376105364 cites W3009105477 @default.
• W4376105364 cites W3011468320 @default.
• W4376105364 cites W3092730721 @default.
• W4376105364 cites W3119152485 @default.
• W4376105364 cites W3156458251 @default.
• W4376105364 cites W3177472573 @default.
• W4376105364 cites W3177828909 @default.
• W4376105364 cites W3194371877 @default.
• W4376105364 cites W4210491595 @default.
• W4376105364 cites W4213296419 @default.
• W4376105364 cites W4223551334 @default.
• W4376105364 cites W4306168503 @default.
• W4376105364 cites W4317475595 @default.
• W4376105364 cites W4317478153 @default.
• W4376105364 cites W4321442616 @default.
• W4376105364 doi "https://doi.org/10.1021/acs.jafc.3c01492" @default.
• W4376105364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37162369" @default.
• W4376105364 hasPublicationYear "2023" @default.
• W4376105364 type Work @default.
• W4376105364 citedByCount "1" @default.
• W4376105364 crossrefType "journal-article" @default.
• W4376105364 hasAuthorship W4376105364A5044478520 @default.
• W4376105364 hasAuthorship W4376105364A5053117100 @default.
• W4376105364 hasAuthorship W4376105364A5091393671 @default.
• W4376105364 hasAuthorship W4376105364A5091546829 @default.
• W4376105364 hasConcept C104317684 @default.
• W4376105364 hasConcept C181199279 @default.
• W4376105364 hasConcept C2776260651 @default.
• W4376105364 hasConcept C2780022147 @default.
• W4376105364 hasConcept C2780069284 @default.
• W4376105364 hasConcept C2780962900 @default.
• W4376105364 hasConcept C28781525 @default.
• W4376105364 hasConcept C553450214 @default.
• W4376105364 hasConcept C55493867 @default.
• W4376105364 hasConcept C86803240 @default.
• W4376105364 hasConceptScore W4376105364C104317684 @default.
• W4376105364 hasConceptScore W4376105364C181199279 @default.
• W4376105364 hasConceptScore W4376105364C2776260651 @default.
• W4376105364 hasConceptScore W4376105364C2780022147 @default.
• W4376105364 hasConceptScore W4376105364C2780069284 @default.
• W4376105364 hasConceptScore W4376105364C2780962900 @default.
• W4376105364 hasConceptScore W4376105364C28781525 @default.
• W4376105364 hasConceptScore W4376105364C553450214 @default.
• W4376105364 hasConceptScore W4376105364C55493867 @default.
• W4376105364 hasConceptScore W4376105364C86803240 @default.
• W4376105364 hasFunder F4320321114 @default.
• W4376105364 hasIssue "20" @default.
• W4376105364 hasLocation W43761053641 @default.
• W4376105364 hasLocation W43761053642 @default.
• W4376105364 hasOpenAccess W4376105364 @default.
• W4376105364 hasPrimaryLocation W43761053641 @default.
• W4376105364 hasRelatedWork W197263901 @default.
• W4376105364 hasRelatedWork W1991824533 @default.
• W4376105364 hasRelatedWork W2018560381 @default.
• W4376105364 hasRelatedWork W2035801704 @default.
• W4376105364 hasRelatedWork W2292789524 @default.
• W4376105364 hasRelatedWork W2576161661 @default.
• W4376105364 hasRelatedWork W2982551297 @default.
• W4376105364 hasRelatedWork W3023190156 @default.

• next