Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376105605> ?p ?o ?g. }
- W4376105605 endingPage "977" @default.
- W4376105605 startingPage "969" @default.
- W4376105605 abstract "Study Design. Prospective pharmacoepidemiologic study. Objective. To investigate clinical and sociodemographic factors associated with persistent opioid use in the years following spine surgery among patients with persistent opioid use preceding lumbar spine surgery. Summary of Background Data. It is unknown whether successful spine surgery leads to a cessation of preoperative persistent opioid use. Materials and Methods. Data from the Norwegian Registry for Spine Surgery and the Norwegian Prescription Database were linked for patients operated for degenerative lumbar spine disorders between 2007 and 2017. The primary outcome measure was persistent opioid use in the second year after surgery. Functional disability was measured with the Oswestry Disability Index (ODI). Factors associated with persistent opioid use in the year before, and two years following, surgery were identified using multivariable logistic regression analysis. The variables included in the analysis were selected based on their demonstrated role in prior studies. Results. The prevalence of persistent opioid use was 8.7% in the year before surgery. Approximately two-thirds of patients also met the criteria for persistent opioid use the second year after surgery. Among patients who did not meet the criteria for persistent opioid use the year before surgery, 991 (3.3%) patients developed persistent opioid use in the second year following surgery. The strongest association was exhibited by high doses of benzodiazepines in the year preceding surgery (OR 1.7, 95% CI 1.26 to 2.19, P<0.001). Among patients without persistent opioid use, the most influential factor associated with new-onset persistent opioid use in the second year after surgery was the use of high doses of benzodiazepines (OR 1.8, 95% CI 1.26 to 2.44, P<0.001), high doses of z-hypnotics (OR 2.6, 95% CI 2.10 to 3.23, P<0.001) and previous surgery at the same lumbar level (OR 1.37, 95% CI 1.11 to 1.68, P=0.003). Conclusion. A substantial proportion of patients reported sustained opioid use after surgery. Patients with persistent opioid use before surgery should be supported to taper off opioid treatment. Special efforts appear to be required to taper off opioid use in patients using high doses of benzodiazepines. Level of Evidence. 2; Prospective observational study." @default.
- W4376105605 created "2023-05-12" @default.
- W4376105605 creator A5006464726 @default.
- W4376105605 creator A5034935855 @default.
- W4376105605 creator A5036697478 @default.
- W4376105605 creator A5037337687 @default.
- W4376105605 creator A5062394652 @default.
- W4376105605 creator A5069598254 @default.
- W4376105605 creator A5082484204 @default.
- W4376105605 date "2023-05-08" @default.
- W4376105605 modified "2023-10-16" @default.
- W4376105605 title "Persistent Use of Prescription Opioids Before and After Lumbar Spine Surgery" @default.
- W4376105605 cites W100098653 @default.
- W4376105605 cites W1746077325 @default.
- W4376105605 cites W1845987094 @default.
- W4376105605 cites W1865885977 @default.
- W4376105605 cites W1886671350 @default.
- W4376105605 cites W1918781854 @default.
- W4376105605 cites W1948003901 @default.
- W4376105605 cites W1965999023 @default.
- W4376105605 cites W1974992958 @default.
- W4376105605 cites W1984986783 @default.
- W4376105605 cites W2014112647 @default.
- W4376105605 cites W2015986868 @default.
- W4376105605 cites W2019400522 @default.
- W4376105605 cites W2024012275 @default.
- W4376105605 cites W2032462160 @default.
- W4376105605 cites W2046967920 @default.
- W4376105605 cites W2141580828 @default.
- W4376105605 cites W2156646026 @default.
- W4376105605 cites W2561663951 @default.
- W4376105605 cites W2586619856 @default.
- W4376105605 cites W2597966538 @default.
- W4376105605 cites W2762190328 @default.
- W4376105605 cites W2792728773 @default.
- W4376105605 cites W2808806962 @default.
- W4376105605 cites W2884196354 @default.
- W4376105605 cites W2889674674 @default.
- W4376105605 cites W2907408736 @default.
- W4376105605 cites W2912520537 @default.
- W4376105605 cites W2998953385 @default.
- W4376105605 cites W3011664963 @default.
- W4376105605 cites W3037455647 @default.
- W4376105605 cites W3037692129 @default.
- W4376105605 cites W3186284651 @default.
- W4376105605 cites W4205239825 @default.
- W4376105605 cites W4210397959 @default.
- W4376105605 cites W4225400058 @default.
- W4376105605 cites W4295014339 @default.
- W4376105605 cites W4297963786 @default.
- W4376105605 cites W4300981863 @default.
- W4376105605 cites W4306733221 @default.
- W4376105605 cites W4310131935 @default.
- W4376105605 cites W4327600907 @default.
- W4376105605 doi "https://doi.org/10.1097/brs.0000000000004710" @default.
- W4376105605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37163646" @default.
- W4376105605 hasPublicationYear "2023" @default.
- W4376105605 type Work @default.
- W4376105605 citedByCount "0" @default.
- W4376105605 crossrefType "journal-article" @default.
- W4376105605 hasAuthorship W4376105605A5006464726 @default.
- W4376105605 hasAuthorship W4376105605A5034935855 @default.
- W4376105605 hasAuthorship W4376105605A5036697478 @default.
- W4376105605 hasAuthorship W4376105605A5037337687 @default.
- W4376105605 hasAuthorship W4376105605A5062394652 @default.
- W4376105605 hasAuthorship W4376105605A5069598254 @default.
- W4376105605 hasAuthorship W4376105605A5082484204 @default.
- W4376105605 hasConcept C126322002 @default.
- W4376105605 hasConcept C138885662 @default.
- W4376105605 hasConcept C141071460 @default.
- W4376105605 hasConcept C142724271 @default.
- W4376105605 hasConcept C151956035 @default.
- W4376105605 hasConcept C170493617 @default.
- W4376105605 hasConcept C188816634 @default.
- W4376105605 hasConcept C204787440 @default.
- W4376105605 hasConcept C2426938 @default.
- W4376105605 hasConcept C2775998654 @default.
- W4376105605 hasConcept C2780907711 @default.
- W4376105605 hasConcept C2781063702 @default.
- W4376105605 hasConcept C41895202 @default.
- W4376105605 hasConcept C44575665 @default.
- W4376105605 hasConcept C63428231 @default.
- W4376105605 hasConcept C71924100 @default.
- W4376105605 hasConcept C98274493 @default.
- W4376105605 hasConceptScore W4376105605C126322002 @default.
- W4376105605 hasConceptScore W4376105605C138885662 @default.
- W4376105605 hasConceptScore W4376105605C141071460 @default.
- W4376105605 hasConceptScore W4376105605C142724271 @default.
- W4376105605 hasConceptScore W4376105605C151956035 @default.
- W4376105605 hasConceptScore W4376105605C170493617 @default.
- W4376105605 hasConceptScore W4376105605C188816634 @default.
- W4376105605 hasConceptScore W4376105605C204787440 @default.
- W4376105605 hasConceptScore W4376105605C2426938 @default.
- W4376105605 hasConceptScore W4376105605C2775998654 @default.
- W4376105605 hasConceptScore W4376105605C2780907711 @default.
- W4376105605 hasConceptScore W4376105605C2781063702 @default.
- W4376105605 hasConceptScore W4376105605C41895202 @default.
- W4376105605 hasConceptScore W4376105605C44575665 @default.