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• W4376113391 startingPage "114233" @default.
• W4376113391 abstract "Sign-tracking is a behavior with relevance to cue-triggered relapse addiction, a Pavlovian conditioned approach behavior directed at the conditioned stimulus. The study examined one strategy for reducing the magnetic pull of drug-associated conditioned stimuli, using selective serotonin reuptake inhibitors (SSRIs) citalopram (0, 10, and 20 mg/kg), escitalopram (0, 10, and 20 mg/kg) and fluoxetine (0, 5, and 10 mg/kg). Male Sprague-Dawley rats were first trained in a standard sign-tracking task and then acutely administered these drugs in a series of three experiments. In each study, it was found that measures of sign-tracking were reduced, although effects on goal-tracking were different between drugs. This study provides evidence that administration of serotonergic antidepressants is effective in reducing sign-tracking and may have some efficacy in preventing cue-triggered relapse." @default.
• W4376113391 created "2023-05-12" @default.
• W4376113391 creator A5069150711 @default.
• W4376113391 date "2023-09-01" @default.
• W4376113391 modified "2023-09-23" @default.
• W4376113391 title "Effects of three serotonin reuptake inhibitors on sign-tracking in male Sprague-Dawley rats" @default.
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• W4376113391 doi "https://doi.org/10.1016/j.physbeh.2023.114233" @default.
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