Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376128468> ?p ?o ?g. }
- W4376128468 abstract "Surgical resection is the most common approach for the treatment of osteosarcoma. However, two major complications, including residual tumor cells and large bone defects, often arise from the surgical resection of osteosarcoma. Discovering new strategies for programmatically solving the two above-mentioned puzzles has become a worldwide challenge. Herein, a novel one-step strategy is reported for natural phenolic acid planted nanohybrids with desired physicochemical properties and steerable photothermal effects for efficacious osteosarcoma suppression and bone healing. Nanohybrids are prepared based on the self-assembly of chlorogenic acid and gold nanorods through robust Au-catechol interface actions, featuring precise nanostructures, great water solubility, good stability, and adjustable hyperthermia generating capacity. As expected, on the one hand, these integrated nanohybrids can severely trigger apoptosis and suppress tumor growth with strong hyperthermia. On the other hand, with controllable mild NIR irradiation, the nanohybrids promote the expression of heat shock proteins and induce prominent osteogenic differentiation. This work initiates a brand-new strategy for assisting osteosarcoma surgical excision to resolve the blockage of residual tumor cells elimination and bone regeneration." @default.
- W4376128468 created "2023-05-12" @default.
- W4376128468 creator A5004675986 @default.
- W4376128468 creator A5015057905 @default.
- W4376128468 creator A5024846921 @default.
- W4376128468 creator A5028154943 @default.
- W4376128468 creator A5032072875 @default.
- W4376128468 creator A5046044862 @default.
- W4376128468 creator A5055722039 @default.
- W4376128468 creator A5062854702 @default.
- W4376128468 date "2023-05-19" @default.
- W4376128468 modified "2023-09-24" @default.
- W4376128468 title "Natural Chlorogenic Acid Planted Nanohybrids with Steerable Hyperthermia for Osteosarcoma Suppression and Bone Regeneration" @default.
- W4376128468 cites W1980088710 @default.
- W4376128468 cites W1986690159 @default.
- W4376128468 cites W2003213153 @default.
- W4376128468 cites W2021437500 @default.
- W4376128468 cites W2046803956 @default.
- W4376128468 cites W2057293894 @default.
- W4376128468 cites W2058374592 @default.
- W4376128468 cites W2092858957 @default.
- W4376128468 cites W2154577831 @default.
- W4376128468 cites W2182373365 @default.
- W4376128468 cites W2269026190 @default.
- W4376128468 cites W2301813316 @default.
- W4376128468 cites W2336387005 @default.
- W4376128468 cites W2559830479 @default.
- W4376128468 cites W2593100393 @default.
- W4376128468 cites W2600572285 @default.
- W4376128468 cites W2763046181 @default.
- W4376128468 cites W2767209834 @default.
- W4376128468 cites W2801389248 @default.
- W4376128468 cites W2803132938 @default.
- W4376128468 cites W2883055543 @default.
- W4376128468 cites W2885073214 @default.
- W4376128468 cites W2888878293 @default.
- W4376128468 cites W2890981759 @default.
- W4376128468 cites W2891730151 @default.
- W4376128468 cites W2903740926 @default.
- W4376128468 cites W2940917005 @default.
- W4376128468 cites W2953503600 @default.
- W4376128468 cites W2955724393 @default.
- W4376128468 cites W2960558416 @default.
- W4376128468 cites W2976837897 @default.
- W4376128468 cites W2990368517 @default.
- W4376128468 cites W3005478486 @default.
- W4376128468 cites W3011757764 @default.
- W4376128468 cites W3023715334 @default.
- W4376128468 cites W3028554178 @default.
- W4376128468 cites W3036581531 @default.
- W4376128468 cites W3086473620 @default.
- W4376128468 cites W3117612948 @default.
- W4376128468 cites W3127107918 @default.
- W4376128468 cites W3137619198 @default.
- W4376128468 cites W3167958127 @default.
- W4376128468 cites W3175162752 @default.
- W4376128468 cites W3182160131 @default.
- W4376128468 cites W3183536837 @default.
- W4376128468 cites W3191067701 @default.
- W4376128468 cites W3193641074 @default.
- W4376128468 cites W3193993111 @default.
- W4376128468 cites W3195593345 @default.
- W4376128468 cites W4200331153 @default.
- W4376128468 cites W4205472863 @default.
- W4376128468 cites W4210404924 @default.
- W4376128468 cites W4210611210 @default.
- W4376128468 cites W4211247370 @default.
- W4376128468 cites W4213009909 @default.
- W4376128468 cites W4213373273 @default.
- W4376128468 cites W4214915953 @default.
- W4376128468 cites W4220829155 @default.
- W4376128468 cites W4221017746 @default.
- W4376128468 cites W4223638250 @default.
- W4376128468 cites W4223900802 @default.
- W4376128468 cites W4224289599 @default.
- W4376128468 cites W4245495770 @default.
- W4376128468 cites W4281646258 @default.
- W4376128468 cites W4306147716 @default.
- W4376128468 cites W4306168166 @default.
- W4376128468 cites W4308054815 @default.
- W4376128468 cites W4308372579 @default.
- W4376128468 cites W4311292030 @default.
- W4376128468 doi "https://doi.org/10.1002/adhm.202300325" @default.
- W4376128468 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37167574" @default.
- W4376128468 hasPublicationYear "2023" @default.
- W4376128468 type Work @default.
- W4376128468 citedByCount "0" @default.
- W4376128468 crossrefType "journal-article" @default.
- W4376128468 hasAuthorship W4376128468A5004675986 @default.
- W4376128468 hasAuthorship W4376128468A5015057905 @default.
- W4376128468 hasAuthorship W4376128468A5024846921 @default.
- W4376128468 hasAuthorship W4376128468A5028154943 @default.
- W4376128468 hasAuthorship W4376128468A5032072875 @default.
- W4376128468 hasAuthorship W4376128468A5046044862 @default.
- W4376128468 hasAuthorship W4376128468A5055722039 @default.
- W4376128468 hasAuthorship W4376128468A5062854702 @default.
- W4376128468 hasConcept C126322002 @default.
- W4376128468 hasConcept C136229726 @default.
- W4376128468 hasConcept C171056886 @default.
- W4376128468 hasConcept C171250308 @default.