Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376130918> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4376130918 abstract "To research the effects of autonomic neuropathy of the digestive system induced by bortezomib on clinical efficacy and quality of life.A total of 150 patients with newly diagnosed multiple myeloma (MM) were hospitalized in our department from January 2018 to December 2021, and treated with bortezomib-based combination regimens. To observe the incidence of autonomic neuropathy of the digestive system and analyse the correlations between the severity of autonomic neuropathy and the efficacy, survival, age, underlying diseases and personal history.The incidence of autonomic neuropathy of the digestive system was 60.0%. The overall response rate (ORR), 2-year progression-free survival (PFS) rate and 2-year overall survival (OS) rate in the grade 3 group of autonomic neuropathy were significantly lower than those in the grade 1-2 group, and the differences were statistically significant (P < 0.05). Age, constipation, diabetes, fracture/spinal cord compression in bed and history of alcoholism were positively correlated with the risk of autonomic neuropathy of the digestive system (P < 0.05). The autonomic neuropathy of the digestive system was significantly alleviated in most patients after the timely adjustment of the treatment regimen, and bortezomib could continue to be administered.The incidence of autonomic neuropathy of the digestive system induced by bortezomib is high, and its severity is closely related to efficacy, advanced age, constipation, diabetes, fracture/spinal cord compression in bed and history of alcoholism. Early detection and early treatment are necessary to better treat the disease and reverse the autonomic neuropathy." @default.
- W4376130918 created "2023-05-12" @default.
- W4376130918 creator A5014030085 @default.
- W4376130918 creator A5046597133 @default.
- W4376130918 creator A5049032815 @default.
- W4376130918 creator A5090201830 @default.
- W4376130918 date "2023-05-11" @default.
- W4376130918 modified "2023-09-23" @default.
- W4376130918 title "Study on autonomic neuropathy of the digestive system caused by bortezomib in the treatment of multiple myeloma" @default.
- W4376130918 cites W1996860716 @default.
- W4376130918 cites W2001160758 @default.
- W4376130918 cites W2069868358 @default.
- W4376130918 cites W2144728882 @default.
- W4376130918 cites W2486629951 @default.
- W4376130918 cites W2508934129 @default.
- W4376130918 cites W2557975627 @default.
- W4376130918 cites W2605384785 @default.
- W4376130918 cites W2623549118 @default.
- W4376130918 cites W2792903930 @default.
- W4376130918 cites W2803122042 @default.
- W4376130918 cites W2883151633 @default.
- W4376130918 cites W2889531115 @default.
- W4376130918 cites W2954389199 @default.
- W4376130918 cites W2971235367 @default.
- W4376130918 cites W3049745533 @default.
- W4376130918 cites W3083679990 @default.
- W4376130918 cites W3125503555 @default.
- W4376130918 cites W4210734847 @default.
- W4376130918 cites W4281551651 @default.
- W4376130918 doi "https://doi.org/10.1080/16078454.2023.2210907" @default.
- W4376130918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37166129" @default.
- W4376130918 hasPublicationYear "2023" @default.
- W4376130918 type Work @default.
- W4376130918 citedByCount "0" @default.
- W4376130918 crossrefType "journal-article" @default.
- W4376130918 hasAuthorship W4376130918A5014030085 @default.
- W4376130918 hasAuthorship W4376130918A5046597133 @default.
- W4376130918 hasAuthorship W4376130918A5049032815 @default.
- W4376130918 hasAuthorship W4376130918A5090201830 @default.
- W4376130918 hasBestOaLocation W43761309181 @default.
- W4376130918 hasConcept C120665830 @default.
- W4376130918 hasConcept C121332964 @default.
- W4376130918 hasConcept C126322002 @default.
- W4376130918 hasConcept C141071460 @default.
- W4376130918 hasConcept C2776364478 @default.
- W4376130918 hasConcept C2776715637 @default.
- W4376130918 hasConcept C2777478702 @default.
- W4376130918 hasConcept C2777480322 @default.
- W4376130918 hasConcept C2781112942 @default.
- W4376130918 hasConcept C54355233 @default.
- W4376130918 hasConcept C61511704 @default.
- W4376130918 hasConcept C71924100 @default.
- W4376130918 hasConcept C81885089 @default.
- W4376130918 hasConcept C86803240 @default.
- W4376130918 hasConcept C90924648 @default.
- W4376130918 hasConceptScore W4376130918C120665830 @default.
- W4376130918 hasConceptScore W4376130918C121332964 @default.
- W4376130918 hasConceptScore W4376130918C126322002 @default.
- W4376130918 hasConceptScore W4376130918C141071460 @default.
- W4376130918 hasConceptScore W4376130918C2776364478 @default.
- W4376130918 hasConceptScore W4376130918C2776715637 @default.
- W4376130918 hasConceptScore W4376130918C2777478702 @default.
- W4376130918 hasConceptScore W4376130918C2777480322 @default.
- W4376130918 hasConceptScore W4376130918C2781112942 @default.
- W4376130918 hasConceptScore W4376130918C54355233 @default.
- W4376130918 hasConceptScore W4376130918C61511704 @default.
- W4376130918 hasConceptScore W4376130918C71924100 @default.
- W4376130918 hasConceptScore W4376130918C81885089 @default.
- W4376130918 hasConceptScore W4376130918C86803240 @default.
- W4376130918 hasConceptScore W4376130918C90924648 @default.
- W4376130918 hasFunder F4320318379 @default.
- W4376130918 hasIssue "1" @default.
- W4376130918 hasLocation W43761309181 @default.
- W4376130918 hasLocation W43761309182 @default.
- W4376130918 hasOpenAccess W4376130918 @default.
- W4376130918 hasPrimaryLocation W43761309181 @default.
- W4376130918 hasRelatedWork W107681997 @default.
- W4376130918 hasRelatedWork W2063424779 @default.
- W4376130918 hasRelatedWork W2104965094 @default.
- W4376130918 hasRelatedWork W2313089823 @default.
- W4376130918 hasRelatedWork W2377458274 @default.
- W4376130918 hasRelatedWork W2409439928 @default.
- W4376130918 hasRelatedWork W3028919400 @default.
- W4376130918 hasRelatedWork W3048020937 @default.
- W4376130918 hasRelatedWork W3114885162 @default.
- W4376130918 hasRelatedWork W4376130918 @default.
- W4376130918 hasVolume "28" @default.
- W4376130918 isParatext "false" @default.
- W4376130918 isRetracted "false" @default.
- W4376130918 workType "article" @default.