FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376133040> ?p ?o ?g. }

• W4376133040 endingPage "571" @default.
• W4376133040 startingPage "571" @default.
• W4376133040 abstract "Importance Hearing loss is the most important modifiable risk factor for cognitive impairment; however, the association of hearing loss with anatomical and functional connectivity is not fully understood. This association may be elucidated by evaluating the findings of newer imaging technologies. Objectives To evaluate the association of hearing loss with anatomical and functional connectivity in patients with mild cognitive impairment (MCI) by using multimodal imaging technology. Design, Setting, and Participants This was a prospective cross-sectional study of patients with MCI under the care of a neurology clinic at the Soonchunhyang University Bucheon Hospital (Republic of Korea) from April to September 2021. Data were analyzed from April 1 to June 30, 2022. Main Outcomes and Measures Pure tone averages (PTA) and word recognition scores were used to measure hearing acuity. Magnetic resonance imaging (MRI) and positron emission tomography scans of the brain were used to assess functional and anatomical connectivity. Results of diffusion MRI, voxel- and surface-based morphometric imaging, and global brain amyloid standardized uptake ratio were analyzed. Neuroimaging parameters of patients with MCI plus hearing loss were compared with those of patients with MCI and no hearing loss. Correlation analyses among neuroimaging parameters, PTA, and word recognition scores were performed. Results Of 48 patients with MCI, 30 (62.5%) had hearing loss (PTA &amp;gt;25 dB) and 18 (37.5%) did not (PTA ≤25 dB). Median (IQR) age was 73.5 (69.0-78.0) years in the group with hearing loss and 75.0 (65.0-78.0) years in the group with normal hearing; there were 20 (66.7%) and 14 (77.8%) women in each group, respectively. The group with MCI plus hearing loss demonstrated decreased functional connectivity between the bilateral insular and anterior divisions of the cingulate cortex, and decreased fractional anisotropy in the bilateral fornix, corpus callosum forceps major and tapetum, left parahippocampal cingulum, and left superior thalamic radiation. Fractional anisotropy in the corpus callosum forceps major and bilateral parahippocampal cingulum negatively correlated with the severity of hearing loss shown by PTA testing. The 2 groups were not significantly different in global β-amyloid uptake, gray matter volume, and cortical thickness. Conclusion and Relevance The findings of this prospective cross-sectional study suggest that alterations in the salience network may contribute to the neural basis of cognitive impairment associated with hearing loss in patients who are on the Alzheimer disease continuum." @default.
• W4376133040 created "2023-05-12" @default.
• W4376133040 creator A5004522965 @default.
• W4376133040 creator A5009816420 @default.
• W4376133040 creator A5037868500 @default.
• W4376133040 creator A5062551982 @default.
• W4376133040 creator A5069043281 @default.
• W4376133040 creator A5072780051 @default.
• W4376133040 creator A5078101542 @default.
• W4376133040 creator A5088757263 @default.
• W4376133040 date "2023-07-01" @default.
• W4376133040 modified "2023-10-16" @default.
• W4376133040 title "Association of Hearing Loss With Anatomical and Functional Connectivity in Patients With Mild Cognitive Impairment" @default.
• W4376133040 cites W1998835792 @default.
• W4376133040 cites W1999890357 @default.
• W4376133040 cites W2029597341 @default.
• W4376133040 cites W2037145190 @default.
• W4376133040 cites W2041748723 @default.
• W4376133040 cites W2071794819 @default.
• W4376133040 cites W2122410839 @default.
• W4376133040 cites W2122522567 @default.
• W4376133040 cites W2123719421 @default.
• W4376133040 cites W2130654277 @default.
• W4376133040 cites W2136022845 @default.
• W4376133040 cites W2137918406 @default.
• W4376133040 cites W2156515629 @default.
• W4376133040 cites W2163452374 @default.
• W4376133040 cites W2167840686 @default.
• W4376133040 cites W2328613904 @default.
• W4376133040 cites W2416032883 @default.
• W4376133040 cites W2775253012 @default.
• W4376133040 cites W2776509557 @default.
• W4376133040 cites W2891995230 @default.
• W4376133040 cites W2897943730 @default.
• W4376133040 cites W2914124137 @default.
• W4376133040 cites W2924644334 @default.
• W4376133040 cites W2943398266 @default.
• W4376133040 cites W2950773127 @default.
• W4376133040 cites W2952835181 @default.
• W4376133040 cites W2984087519 @default.
• W4376133040 cites W2987803460 @default.
• W4376133040 cites W3011485854 @default.
• W4376133040 cites W3046275966 @default.
• W4376133040 cites W3081039494 @default.
• W4376133040 cites W3137280506 @default.
• W4376133040 cites W3186899711 @default.
• W4376133040 cites W4220663587 @default.
• W4376133040 cites W4241456134 @default.
• W4376133040 cites W4241635949 @default.
• W4376133040 cites W4245912083 @default.
• W4376133040 cites W4254878997 @default.
• W4376133040 cites W4256106179 @default.
• W4376133040 cites W4283273580 @default.
• W4376133040 cites W4304140374 @default.
• W4376133040 cites W4312438656 @default.
• W4376133040 doi "https://doi.org/10.1001/jamaoto.2023.0824" @default.
• W4376133040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37166823" @default.
• W4376133040 hasPublicationYear "2023" @default.
• W4376133040 type Work @default.
• W4376133040 citedByCount "1" @default.
• W4376133040 countsByYear W43761330402023 @default.
• W4376133040 crossrefType "journal-article" @default.
• W4376133040 hasAuthorship W4376133040A5004522965 @default.
• W4376133040 hasAuthorship W4376133040A5009816420 @default.
• W4376133040 hasAuthorship W4376133040A5037868500 @default.
• W4376133040 hasAuthorship W4376133040A5062551982 @default.
• W4376133040 hasAuthorship W4376133040A5069043281 @default.
• W4376133040 hasAuthorship W4376133040A5072780051 @default.
• W4376133040 hasAuthorship W4376133040A5078101542 @default.
• W4376133040 hasAuthorship W4376133040A5088757263 @default.
• W4376133040 hasConcept C118552586 @default.
• W4376133040 hasConcept C126838900 @default.
• W4376133040 hasConcept C143409427 @default.
• W4376133040 hasConcept C16568411 @default.
• W4376133040 hasConcept C169900460 @default.
• W4376133040 hasConcept C2775842073 @default.
• W4376133040 hasConcept C2780493683 @default.
• W4376133040 hasConcept C548259974 @default.
• W4376133040 hasConcept C58693492 @default.
• W4376133040 hasConcept C71924100 @default.
• W4376133040 hasConceptScore W4376133040C118552586 @default.
• W4376133040 hasConceptScore W4376133040C126838900 @default.
• W4376133040 hasConceptScore W4376133040C143409427 @default.
• W4376133040 hasConceptScore W4376133040C16568411 @default.
• W4376133040 hasConceptScore W4376133040C169900460 @default.
• W4376133040 hasConceptScore W4376133040C2775842073 @default.
• W4376133040 hasConceptScore W4376133040C2780493683 @default.
• W4376133040 hasConceptScore W4376133040C548259974 @default.
• W4376133040 hasConceptScore W4376133040C58693492 @default.
• W4376133040 hasConceptScore W4376133040C71924100 @default.
• W4376133040 hasIssue "7" @default.
• W4376133040 hasLocation W43761330401 @default.
• W4376133040 hasLocation W43761330402 @default.
• W4376133040 hasOpenAccess W4376133040 @default.
• W4376133040 hasPrimaryLocation W43761330401 @default.
• W4376133040 hasRelatedWork W2092769255 @default.
• W4376133040 hasRelatedWork W2136289487 @default.
• W4376133040 hasRelatedWork W2161096528 @default.

• next