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- W4376133090 abstract "BACKGROUND: Urinary incontinence (UI) is a common and frustrating condition that affects patients’ quality of life as well as the Healthcare systems. Currently, the most severe cases of UI are treated using implanted, invasive artificial sphincters. We propose an innovative, minimally invasive magnetic endourethral sphincter for the treatment of stress UI (SUI) in patients for whom previous medical and surgical treatments have failed.METHODS: Six patients with severe SUI were enrolled at a single center and underwent cystoscopic sphincter implantation. After 10 days, correct device position was confirmed by ultrasonography. The sphincter was explanted after 28 days.RESULTS: In all patients, the sphincter was successfully implanted using an endoscopic approach. One patient reached the end of the pilot test (28 days) with the sphincter correctly placed. Patients’ responses on the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form questionnaire improved from a score of 18 out of 21 at the screening visit (UI without reasons) to a score of 3 out of 21 (almost perfect continence). No major pain and discomfort were reported.CONCLUSIONS: This study showed the feasibility of sphincter implantation, explantation, and overall tolerability, although a redesign of the sphincter distal part is needed." @default.
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- W4376133090 date "2023-08-01" @default.
- W4376133090 modified "2023-10-02" @default.
- W4376133090 title "A magnetic endourethral sphincter against stress urinary incontinence: preliminary pilot study in humans" @default.
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- W4376133090 doi "https://doi.org/10.23736/s2724-6051.23.05190-x" @default.
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