Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376133604> ?p ?o ?g. }
- W4376133604 abstract "Here, we reported the complete profiling of the crotonylation proteome in common wheat. Through a combination of crotonylation and multi-omics analysis, we identified a TaPGK associated with wheat cold stress. Then, we confirmed the positive role of TaPGK-modulating wheat cold tolerance. Meanwhile, we found that cold stress induced lysine crotonylation of TaPGK. Moreover, we screened a lysine decrotonylase TaSRT1 interacting with TaPGK and found that TaSRT1 negatively regulated wheat cold tolerance. We subsequently demonstrated TaSRT1 inhibiting the accumulation of TaPGK protein, and this inhibition was possibly resulted from decrotonylation of TaPGK by TaSRT1. Transcriptome sequencing indicated that overexpression of TaPGK activated glycolytic key genes and thereby increased pyruvate content. Moreover, we found that exogenous application of pyruvate sharply enhanced wheat cold tolerance. These findings suggest that the TaSRT1-TaPGK model regulating wheat cold tolerance is possibly through mediating pyruvate. This study provided two valuable cold tolerance genes and dissected diverse mechanism of glycolytic pathway involving in wheat cold stress." @default.
- W4376133604 created "2023-05-12" @default.
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- W4376133604 date "2023-05-10" @default.
- W4376133604 modified "2023-09-30" @default.
- W4376133604 title "Global crotonylatome and GWAS revealed a <i>TaSRT1</i> - <i>TaPGK</i> model regulating wheat cold tolerance through mediating pyruvate" @default.
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- W4376133604 doi "https://doi.org/10.1126/sciadv.adg1012" @default.
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