Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376140911> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4376140911 abstract "Abstract Introduction Little is known regarding whether opioid prescriptions following colectomy lead to persistent use. We aimed to determine the prevalence of persistent post-discharge opioid use following colectomy, stratified by preadmission opioid exposure, and identify associated predictors of prolonged use. Methods This cohort study on adults undergoing colectomy between 2010 and 2019 used linked primary (Clinical Practice Research Datalink), and secondary (Hospital Episode Statistics) care data. Patients were categorised as opioid-naïve, currently exposed (opioid prescription 0-6 months before admission) and prior exposed (prescription 6-12 months before admission). Persistent use was defined as needing an opioid prescription within 90 days of hospital discharge, along with another opioid prescription 91 to 180 days after discharge. Multivariable logistic regression analyses were performed to identify predictors of persistent use. Results Of the 93,262 patients, 15,081 (16.2%) were issued at least one opioid prescription within 90 days of discharge. Of these, 45.0% were opioid-naïve, 49.9% currently exposed, and 5.0% prior exposed. From the whole cohort, 7540 (8.1%) developed persistent opioid use. Patients with preoperative opioid exposure had the highest persistent use: 5317 (40.4%) from the currently exposed group and 305 (9.8%) from the prior exposed group, with only 2.5% from the opioid-naïve group. Predictors of persistent use included prior opioid exposure, high deprivation index, multiple comorbidities, White ethnicity, and open surgery. Conclusion After colectomy, more than 1:12 patients continued to receive opioids three months beyond discharge. Minimally invasive surgery was associated with lower risk of persistent opioid use and may represent a modifiable risk factor." @default.
- W4376140911 created "2023-05-12" @default.
- W4376140911 creator A5003031084 @default.
- W4376140911 creator A5003275621 @default.
- W4376140911 creator A5004931608 @default.
- W4376140911 creator A5049880391 @default.
- W4376140911 creator A5062910447 @default.
- W4376140911 date "2023-05-01" @default.
- W4376140911 modified "2023-09-27" @default.
- W4376140911 title "O087 Predictors of persistent opioid use after discharge following colectomy: a population-based cohort study from England" @default.
- W4376140911 doi "https://doi.org/10.1093/bjs/znad101.087" @default.
- W4376140911 hasPublicationYear "2023" @default.
- W4376140911 type Work @default.
- W4376140911 citedByCount "0" @default.
- W4376140911 crossrefType "journal-article" @default.
- W4376140911 hasAuthorship W4376140911A5003031084 @default.
- W4376140911 hasAuthorship W4376140911A5003275621 @default.
- W4376140911 hasAuthorship W4376140911A5004931608 @default.
- W4376140911 hasAuthorship W4376140911A5049880391 @default.
- W4376140911 hasAuthorship W4376140911A5062910447 @default.
- W4376140911 hasBestOaLocation W43761409111 @default.
- W4376140911 hasConcept C121608353 @default.
- W4376140911 hasConcept C126322002 @default.
- W4376140911 hasConcept C151956035 @default.
- W4376140911 hasConcept C167135981 @default.
- W4376140911 hasConcept C170493617 @default.
- W4376140911 hasConcept C194828623 @default.
- W4376140911 hasConcept C201903717 @default.
- W4376140911 hasConcept C2426938 @default.
- W4376140911 hasConcept C2776667177 @default.
- W4376140911 hasConcept C2781063702 @default.
- W4376140911 hasConcept C2908647359 @default.
- W4376140911 hasConcept C42219234 @default.
- W4376140911 hasConcept C526805850 @default.
- W4376140911 hasConcept C71924100 @default.
- W4376140911 hasConcept C72563966 @default.
- W4376140911 hasConcept C98274493 @default.
- W4376140911 hasConcept C99454951 @default.
- W4376140911 hasConceptScore W4376140911C121608353 @default.
- W4376140911 hasConceptScore W4376140911C126322002 @default.
- W4376140911 hasConceptScore W4376140911C151956035 @default.
- W4376140911 hasConceptScore W4376140911C167135981 @default.
- W4376140911 hasConceptScore W4376140911C170493617 @default.
- W4376140911 hasConceptScore W4376140911C194828623 @default.
- W4376140911 hasConceptScore W4376140911C201903717 @default.
- W4376140911 hasConceptScore W4376140911C2426938 @default.
- W4376140911 hasConceptScore W4376140911C2776667177 @default.
- W4376140911 hasConceptScore W4376140911C2781063702 @default.
- W4376140911 hasConceptScore W4376140911C2908647359 @default.
- W4376140911 hasConceptScore W4376140911C42219234 @default.
- W4376140911 hasConceptScore W4376140911C526805850 @default.
- W4376140911 hasConceptScore W4376140911C71924100 @default.
- W4376140911 hasConceptScore W4376140911C72563966 @default.
- W4376140911 hasConceptScore W4376140911C98274493 @default.
- W4376140911 hasConceptScore W4376140911C99454951 @default.
- W4376140911 hasIssue "Supplement_3" @default.
- W4376140911 hasLocation W43761409111 @default.
- W4376140911 hasOpenAccess W4376140911 @default.
- W4376140911 hasPrimaryLocation W43761409111 @default.
- W4376140911 hasRelatedWork W2360736373 @default.
- W4376140911 hasRelatedWork W2767142319 @default.
- W4376140911 hasRelatedWork W2890967794 @default.
- W4376140911 hasRelatedWork W2895285328 @default.
- W4376140911 hasRelatedWork W2939600593 @default.
- W4376140911 hasRelatedWork W2978765478 @default.
- W4376140911 hasRelatedWork W3024703602 @default.
- W4376140911 hasRelatedWork W3091109908 @default.
- W4376140911 hasRelatedWork W3154718948 @default.
- W4376140911 hasRelatedWork W3157198265 @default.
- W4376140911 hasVolume "110" @default.
- W4376140911 isParatext "false" @default.
- W4376140911 isRetracted "false" @default.
- W4376140911 workType "article" @default.