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- W4376155708 abstract "A plethora of studies in animal models and large epidemiological studies in humans have shown that cannabis consumption during adolescence – a critical neurodevelopmental period for human beings – leads to an increased risk of developing mood disorders in adolescence or in young adulthood. Cannabis interacts with the monoaminergic system and with the endogenous cannabinoid system by altering the mechanism of mood regulation. Recent meta-analyses have also pointed out an increased risk for major depression in young adulthood after cannabis consumption in adolescence, even in the absence of pre-existing depression. Moreover, cannabis is also a risk factor for suicidal behaviours and suicide attempts. In summary, clinical studies suggest that cannabis is consumed by young people with depression largely for self-medication; however, its use, even in the absence of pre-morbid conditions, may also increase the risk of developing a mood disorder and can drive impulsive and suicidal behaviours." @default.
- W4376155708 created "2023-05-12" @default.
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- W4376155708 date "2023-06-01" @default.
- W4376155708 modified "2023-10-14" @default.
- W4376155708 title "Cannabis Consumption and Risk of Depression and Suicidal Behaviour" @default.
- W4376155708 doi "https://doi.org/10.1017/9781108943246.013" @default.
- W4376155708 hasPublicationYear "2023" @default.
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