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- W4376223675 abstract "Objective: This study was conducted to investigate polymorphisms of the melanocortin-4 receptor (<i>MC4R</i>) and insulin like growth factor 2 (<i>IGF2</i>) genes and to evaluate the growth traits affected by such polymorphisms in Thai native (Kradon) pigs.Methods: Blood samples and productive data from 91 Kradon pigs were collected. DNA was extracted and quantified, the <i>IGF2</i> and <i>MC4R</i> genes were amplified, and the polymerase chain reaction (PCR) produces were digested using the PCR-restriction fragment length polymorphism (PCR-RFLP) technique. Genotyping was performed, and the association between genotypes and growth traits on the birth and weaning weights were evaluated.Results: The IGF2 intron7 g.162G>C variations in Kradon pigs were found in three genotypes: i) GG, ii) GC, and iii) CC. The GG genotype frequency was the highest followed by the GC and CC genotypes. The frequencies of the G and C alleles were 0.703 and 0.297, respectively. The <i>MC4R</i> genotype was found in only one genotype (GG). The <i>IGF2</i> gene pattern was not associated with birth weight traits, whereas the <i>IGF2</i> gene pattern was related to the weaning weight trait in Kradon pigs. Pigs with the CC and GC genotypes had higher weaning weights than ones with the GG genotype (p<0.001).Conclusion: Thai native Kradon pigs with the CC and GC genotypes of the <i>IGF2</i> gene have higher weaning weights than pigs with the GG genotype." @default.
- W4376223675 created "2023-05-13" @default.
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- W4376223675 date "2023-09-01" @default.
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- W4376223675 title "The variation of IGF2 maker is associated with growth traits in Thai native (Kradon) pigs" @default.
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- W4376223675 doi "https://doi.org/10.5713/ab.22.0431" @default.
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