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- W4376272271 endingPage "168144" @default.
- W4376272271 startingPage "168144" @default.
- W4376272271 abstract "The elucidation of the function of the PINK1 protein kinase and Parkin ubiquitin E3 ligase in the elimination of damaged mitochondria by autophagy (mitophagy) has provided unprecedented understanding of the mechanistic pathways underlying Parkinson's disease (PD). We provide a comprehensive overview of the general importance of autophagy in Parkinson's disease and related disorders of the central nervous system. This reveals a critical link between autophagy and neurodegenerative and neurodevelopmental disorders and suggests that strategies to modulate mitophagy may have greater relevance in the CNS beyond PD." @default.
- W4376272271 created "2023-05-13" @default.
- W4376272271 creator A5004462406 @default.
- W4376272271 creator A5009978283 @default.
- W4376272271 creator A5083210549 @default.
- W4376272271 creator A5084528692 @default.
- W4376272271 date "2023-06-01" @default.
- W4376272271 modified "2023-10-14" @default.
- W4376272271 title "Role of autophagy pathway in Parkinson’s disease and related Genetic Neurological disorders" @default.
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