Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376272485> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W4376272485 abstract "Anthracnose disease, caused by Colletotrichum truncatum, is a destructive fungal disease in soybean worldwide and some demethylation inhibitor fungicides are used to manage it. In this study, the sensitivity of C. truncatum to difenoconazole was determined, and the risk for resistance development of C. truncatum to difenoconazole was also assessed. The results showed that the mean EC50 value was 0.9313 μg/mL and the frequency of sensitivity formed a unimodal distribution. Six stable mutants with a mutation frequency of 8.33 × 10−5 were generated, and resistance factors ranged from 3.00 to 5.81 after 10 successive culture transfers. All mutants exhibited fitness penalties in reduced mycelial growth rate, sporulation and pathogenicity, except for the Ct2-3-5 mutant. Positive cross-resistance was observed between difenoconazole and propiconazole, but not between difenoconazole and prochloraz, pyraclostrobin or fluazinam. One point mutation I463V in CYP51A was found in five resistant mutants. Surprisingly, the homologous I463V mutation has not been observed in other plant pathogens. CYP51A and CYP51B expression increased slightly in the resistant mutants as compared to wild-types when exposed to difenoconazole, but not in the CtR61-2-3f and CtR61-2-4a mutants. In general, a new point mutation, I463V in CYP51A, could be associated with low resistance to difenoconazole in C. truncatum. In the greenhouse assay, control efficacy of difenoconazole on both parental isolates and the mutants increased in a dose dependent manner. Collectively, the resistance risk of C. truncatum to difenoconazole is regarded to be low to moderate, suggesting that difenoconazole can still be reasonably used to control soybean anthracnose." @default.
- W4376272485 created "2023-05-13" @default.
- W4376272485 creator A5005959656 @default.
- W4376272485 creator A5012773093 @default.
- W4376272485 creator A5027737240 @default.
- W4376272485 creator A5043687380 @default.
- W4376272485 creator A5053902228 @default.
- W4376272485 date "2023-05-12" @default.
- W4376272485 modified "2023-09-26" @default.
- W4376272485 title "Analysis of the difenoconazole-resistance risk and its molecular basis in Colletotrichum truncatum from soybean" @default.
- W4376272485 doi "https://doi.org/10.1094/pdis-12-22-2983-re" @default.
- W4376272485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37172974" @default.
- W4376272485 hasPublicationYear "2023" @default.
- W4376272485 type Work @default.
- W4376272485 citedByCount "0" @default.
- W4376272485 crossrefType "journal-article" @default.
- W4376272485 hasAuthorship W4376272485A5005959656 @default.
- W4376272485 hasAuthorship W4376272485A5012773093 @default.
- W4376272485 hasAuthorship W4376272485A5027737240 @default.
- W4376272485 hasAuthorship W4376272485A5043687380 @default.
- W4376272485 hasAuthorship W4376272485A5053902228 @default.
- W4376272485 hasConcept C104317684 @default.
- W4376272485 hasConcept C133479454 @default.
- W4376272485 hasConcept C143065580 @default.
- W4376272485 hasConcept C144027150 @default.
- W4376272485 hasConcept C176944494 @default.
- W4376272485 hasConcept C202751555 @default.
- W4376272485 hasConcept C2777860415 @default.
- W4376272485 hasConcept C2778080818 @default.
- W4376272485 hasConcept C54355233 @default.
- W4376272485 hasConcept C59822182 @default.
- W4376272485 hasConcept C74600772 @default.
- W4376272485 hasConcept C86803240 @default.
- W4376272485 hasConcept C89423630 @default.
- W4376272485 hasConcept C96529984 @default.
- W4376272485 hasConceptScore W4376272485C104317684 @default.
- W4376272485 hasConceptScore W4376272485C133479454 @default.
- W4376272485 hasConceptScore W4376272485C143065580 @default.
- W4376272485 hasConceptScore W4376272485C144027150 @default.
- W4376272485 hasConceptScore W4376272485C176944494 @default.
- W4376272485 hasConceptScore W4376272485C202751555 @default.
- W4376272485 hasConceptScore W4376272485C2777860415 @default.
- W4376272485 hasConceptScore W4376272485C2778080818 @default.
- W4376272485 hasConceptScore W4376272485C54355233 @default.
- W4376272485 hasConceptScore W4376272485C59822182 @default.
- W4376272485 hasConceptScore W4376272485C74600772 @default.
- W4376272485 hasConceptScore W4376272485C86803240 @default.
- W4376272485 hasConceptScore W4376272485C89423630 @default.
- W4376272485 hasConceptScore W4376272485C96529984 @default.
- W4376272485 hasLocation W43762724851 @default.
- W4376272485 hasLocation W43762724852 @default.
- W4376272485 hasOpenAccess W4376272485 @default.
- W4376272485 hasPrimaryLocation W43762724851 @default.
- W4376272485 hasRelatedWork W2180439808 @default.
- W4376272485 hasRelatedWork W2351373333 @default.
- W4376272485 hasRelatedWork W2357007119 @default.
- W4376272485 hasRelatedWork W2361130506 @default.
- W4376272485 hasRelatedWork W2385884983 @default.
- W4376272485 hasRelatedWork W2388571269 @default.
- W4376272485 hasRelatedWork W2530770319 @default.
- W4376272485 hasRelatedWork W3193883282 @default.
- W4376272485 hasRelatedWork W4285180800 @default.
- W4376272485 hasRelatedWork W836436065 @default.
- W4376272485 isParatext "false" @default.
- W4376272485 isRetracted "false" @default.
- W4376272485 workType "article" @default.