Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376289053> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4376289053 endingPage "107185" @default.
- W4376289053 startingPage "107185" @default.
- W4376289053 abstract "To test the hypothesis that intracranial arterial calcification (IAC) is associated with intracranial large artery stenosis (ILAS) and a higher risk of vascular events and mortality.We leveraged data from two cohorts, the New York-Presbyterian Hospital/Columbia University Irving Medical Center Stroke Registry Study (NYP/CUIMC-SRS) and the Northern Manhattan Study (NOMAS) to test our hypotheses. We measured IAC using CT scans of participants in both cohorts and expressed IAC as present (vs not) and in tertiles. For the CUIMC-SRS, demographic, clinical and ILAS status was collected retrospectively. In NOMAS, we used research brain MRI and MRA to define asymptomatic ILAS and covert brain infarcts(CBI). We built models adjusted for demographics and vascular risk factors for cross-sectional and longitudinal analyses.Cross-sectionally, IAC was associated with ILAS in both cohorts (OR 1.78, 95% CI: 1.16-2.73 for ILAS-related stroke in the NYP/CUIMC-SRS and OR 3.07, 95%CI 1.13-8.35 for ILAS-related covert brain infarcts in NOMAS). In a meta-analysis of both cohorts, IAC in the upper (HR 1.25, 95%CI 1.01-1.55) and middle tertile (HR 1.27, 95%CI 1.01-1.59) was associated with higher mortality compared with participants with no IAC. There were no longitudinal associations between IAC and risk of stroke or other vascular events.In these multiethnic populations, IAC is associated with symptomatic and asymptomatic ILAS as well as higher mortality. IAC may be a useful marker of higher mortality, the role of IAC as an imaging marker of risk of stroke is less certain." @default.
- W4376289053 created "2023-05-13" @default.
- W4376289053 creator A5019103144 @default.
- W4376289053 creator A5021756508 @default.
- W4376289053 creator A5022417082 @default.
- W4376289053 creator A5035161117 @default.
- W4376289053 creator A5055183306 @default.
- W4376289053 creator A5062778696 @default.
- W4376289053 creator A5063594630 @default.
- W4376289053 creator A5065239151 @default.
- W4376289053 creator A5070735650 @default.
- W4376289053 creator A5072145703 @default.
- W4376289053 creator A5088034421 @default.
- W4376289053 creator A5088954991 @default.
- W4376289053 date "2023-08-01" @default.
- W4376289053 modified "2023-10-18" @default.
- W4376289053 title "The role of intracranial artery calcification (IAC) in stroke subtype and risk of vascular events" @default.
- W4376289053 cites W1841053439 @default.
- W4376289053 cites W2070310852 @default.
- W4376289053 cites W2134543054 @default.
- W4376289053 cites W2136529991 @default.
- W4376289053 cites W2165402915 @default.
- W4376289053 cites W2253505102 @default.
- W4376289053 cites W2388614218 @default.
- W4376289053 cites W2563893819 @default.
- W4376289053 cites W2586445337 @default.
- W4376289053 cites W2787893909 @default.
- W4376289053 cites W2896236102 @default.
- W4376289053 cites W2901854445 @default.
- W4376289053 cites W2944091999 @default.
- W4376289053 cites W2989847909 @default.
- W4376289053 cites W4225730599 @default.
- W4376289053 doi "https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107185" @default.
- W4376289053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37186970" @default.
- W4376289053 hasPublicationYear "2023" @default.
- W4376289053 type Work @default.
- W4376289053 citedByCount "0" @default.
- W4376289053 crossrefType "journal-article" @default.
- W4376289053 hasAuthorship W4376289053A5019103144 @default.
- W4376289053 hasAuthorship W4376289053A5021756508 @default.
- W4376289053 hasAuthorship W4376289053A5022417082 @default.
- W4376289053 hasAuthorship W4376289053A5035161117 @default.
- W4376289053 hasAuthorship W4376289053A5055183306 @default.
- W4376289053 hasAuthorship W4376289053A5062778696 @default.
- W4376289053 hasAuthorship W4376289053A5063594630 @default.
- W4376289053 hasAuthorship W4376289053A5065239151 @default.
- W4376289053 hasAuthorship W4376289053A5070735650 @default.
- W4376289053 hasAuthorship W4376289053A5072145703 @default.
- W4376289053 hasAuthorship W4376289053A5088034421 @default.
- W4376289053 hasAuthorship W4376289053A5088954991 @default.
- W4376289053 hasConcept C126322002 @default.
- W4376289053 hasConcept C127413603 @default.
- W4376289053 hasConcept C164705383 @default.
- W4376289053 hasConcept C2777910003 @default.
- W4376289053 hasConcept C2780645631 @default.
- W4376289053 hasConcept C71924100 @default.
- W4376289053 hasConcept C78519656 @default.
- W4376289053 hasConceptScore W4376289053C126322002 @default.
- W4376289053 hasConceptScore W4376289053C127413603 @default.
- W4376289053 hasConceptScore W4376289053C164705383 @default.
- W4376289053 hasConceptScore W4376289053C2777910003 @default.
- W4376289053 hasConceptScore W4376289053C2780645631 @default.
- W4376289053 hasConceptScore W4376289053C71924100 @default.
- W4376289053 hasConceptScore W4376289053C78519656 @default.
- W4376289053 hasFunder F4320332161 @default.
- W4376289053 hasIssue "8" @default.
- W4376289053 hasLocation W43762890531 @default.
- W4376289053 hasLocation W43762890532 @default.
- W4376289053 hasOpenAccess W4376289053 @default.
- W4376289053 hasPrimaryLocation W43762890531 @default.
- W4376289053 hasRelatedWork W129423339 @default.
- W4376289053 hasRelatedWork W1987215768 @default.
- W4376289053 hasRelatedWork W1991129960 @default.
- W4376289053 hasRelatedWork W1995188757 @default.
- W4376289053 hasRelatedWork W2007817983 @default.
- W4376289053 hasRelatedWork W2016679923 @default.
- W4376289053 hasRelatedWork W2116001782 @default.
- W4376289053 hasRelatedWork W2943195325 @default.
- W4376289053 hasRelatedWork W4229900919 @default.
- W4376289053 hasRelatedWork W17604275 @default.
- W4376289053 hasVolume "32" @default.
- W4376289053 isParatext "false" @default.
- W4376289053 isRetracted "false" @default.
- W4376289053 workType "article" @default.