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• W4376504414 abstract "As a nexus of routine antibiotic use and zoonotic pathogen presence, the live-stock farming environment is a potential hotspot for the emergence of zoonotic diseases and antibiotic resistant bacteria. Livestock can further facilitate disease transmission by serving as intermediary hosts for pathogens as they undergo evolution prior to a spillover event. In light of this, we are interested in characterizing the microbiome and resistome of dairy workers, whose exposure to the livestock farming environment places them at risk for facilitating community transmission of antibiotic resistant genes and emerging zoonotic diseases.Using shotgun sequencing, we investigated differences in the taxonomy, diversity and gene presence of the human gut microbiome of 10 dairy farm workers and 6 community controls, supplementing these samples with additional publicly available gut metagenomes. We observed greater abundance of tetracycline resistance genes and prevalence of cephamycin resistance genes in dairy workers' metagenomes, and lower average gene diversity. We also found evidence of commensal organism association with plasmid-mediated tetracycline resistance genes in both dairy workers and community controls (including Faecalibacterium prausnitzii, Ligilactobacillus animalis , and Simiaoa sunii ). However, we did not find significant differences in the prevalence of resistance genes or virulence factors overall, nor differences in the taxonomic composition of dairy worker and community control metagenomes.This study presents the first metagenomics analysis of United States dairy workers, providing insights into potential risks of exposure to antibiotics and pathogens in animal farming environments. Previous metagenomic studies of livestock workers in China and Europe have reported increased abundance and carriage of antibiotic resistance genes in livestock workers. While our investigation found no strong evidence for differences in the abundance or carriage of antibiotic resistance genes and virulence factors between dairy worker and community control gut metagenomes, we did observe patterns in the abundance of tetracycline resistance genes and the prevalence of cephamycin resistance genes that is consistent with previous work." @default.
• W4376504414 created "2023-05-15" @default.
• W4376504414 creator A5005338517 @default.
• W4376504414 creator A5015548332 @default.
• W4376504414 creator A5053110644 @default.
• W4376504414 creator A5054725825 @default.
• W4376504414 date "2023-05-12" @default.
• W4376504414 modified "2023-09-27" @default.
• W4376504414 title "Differences in gut metagenomes between dairy workers and community controls: a cross-sectional study" @default.
• W4376504414 cites W1532987327 @default.
• W4376504414 cites W1903024071 @default.
• W4376504414 cites W1958058086 @default.
• W4376504414 cites W1985106082 @default.
• W4376504414 cites W1990452068 @default.
• W4376504414 cites W2004549986 @default.
• W4376504414 cites W2010513968 @default.
• W4376504414 cites W2014775641 @default.
• W4376504414 cites W2025114863 @default.
• W4376504414 cites W2026777696 @default.
• W4376504414 cites W2027266940 @default.
• W4376504414 cites W2034634989 @default.
• W4376504414 cites W2045204781 @default.
• W4376504414 cites W2050849048 @default.
• W4376504414 cites W2052554412 @default.
• W4376504414 cites W2055043387 @default.
• W4376504414 cites W2083501377 @default.
• W4376504414 cites W2084057318 @default.
• W4376504414 cites W2099837668 @default.
• W4376504414 cites W2101571099 @default.
• W4376504414 cites W2108234281 @default.
• W4376504414 cites W2108281900 @default.
• W4376504414 cites W2110417468 @default.
• W4376504414 cites W2111283004 @default.
• W4376504414 cites W2113679889 @default.
• W4376504414 cites W2113785850 @default.
• W4376504414 cites W2119497560 @default.
• W4376504414 cites W2125834258 @default.
• W4376504414 cites W2128769815 @default.
• W4376504414 cites W2131026689 @default.
• W4376504414 cites W2133897686 @default.
• W4376504414 cites W2138122982 @default.
• W4376504414 cites W2140731876 @default.
• W4376504414 cites W2143485490 @default.
• W4376504414 cites W2149118757 @default.
• W4376504414 cites W2155606054 @default.
• W4376504414 cites W2162088497 @default.
• W4376504414 cites W2166562121 @default.
• W4376504414 cites W2170551349 @default.
• W4376504414 cites W2328023807 @default.
• W4376504414 cites W2343917624 @default.
• W4376504414 cites W2344149427 @default.
• W4376504414 cites W2588090080 @default.
• W4376504414 cites W2765485035 @default.
• W4376504414 cites W2769807545 @default.
• W4376504414 cites W2787902098 @default.
• W4376504414 cites W2792021903 @default.
• W4376504414 cites W2794891594 @default.
• W4376504414 cites W2898402099 @default.
• W4376504414 cites W2900750626 @default.
• W4376504414 cites W2903537183 @default.
• W4376504414 cites W2929934094 @default.
• W4376504414 cites W2947038645 @default.
• W4376504414 cites W2951160681 @default.
• W4376504414 cites W2951912016 @default.
• W4376504414 cites W2952597168 @default.
• W4376504414 cites W2953093188 @default.
• W4376504414 cites W2962703075 @default.
• W4376504414 cites W2963064180 @default.
• W4376504414 cites W2965005210 @default.
• W4376504414 cites W2965564399 @default.
• W4376504414 cites W2980278484 @default.
• W4376504414 cites W2982531601 @default.
• W4376504414 cites W2990618091 @default.
• W4376504414 cites W2998523622 @default.
• W4376504414 cites W3011457913 @default.
• W4376504414 cites W3021893467 @default.
• W4376504414 cites W3029686768 @default.
• W4376504414 cites W3043561813 @default.
• W4376504414 cites W3085212067 @default.
• W4376504414 cites W3092434457 @default.
• W4376504414 cites W3112234114 @default.
• W4376504414 cites W3119507732 @default.
• W4376504414 cites W3121495243 @default.
• W4376504414 cites W3125247928 @default.
• W4376504414 cites W3125845881 @default.
• W4376504414 cites W3145516664 @default.
• W4376504414 cites W3158873216 @default.
• W4376504414 cites W3159504416 @default.
• W4376504414 cites W3192503388 @default.
• W4376504414 cites W3194499026 @default.
• W4376504414 cites W3194700300 @default.
• W4376504414 cites W3202352160 @default.
• W4376504414 cites W4200091812 @default.
• W4376504414 cites W4200127170 @default.
• W4376504414 cites W4200405976 @default.
• W4376504414 cites W4210308072 @default.
• W4376504414 cites W4211040199 @default.
• W4376504414 cites W4220795136 @default.
• W4376504414 cites W4225155554 @default.
• W4376504414 cites W4225854522 @default.

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