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- W4376609476 abstract "Abstract It is well known that vitamin D’s general immunomodulatory actions are helpful in viral infections and that a shortage is linked to a more serious prognosis for Covid-19. In this sistematic review, we examined the existing literature on evidence as to whether there is also link between vitamin D range levels in pediatric population and the outcome of the Covid-19 infection. We looked for studies that measured vitamin D blood concentrations and examined the effects of vitamin D supplementation in young infected patients. Vitamin D may decrease the risk of respiratory infections in a number of ways through its interactions with numerous cells, including by decreasing viral survival and replication, reducing the cytokine storm, raising angiotensin-converting enzyme 2 concentrations (ACE2) while not damaging the endothelial integrity. The incidence or severity of Covid-19 is linked with blood 25-hydroxyvitamin D concentrations, according to many observational studies. However experimental verification is still needed. Given their safety and broad therapeutic window, vitamin D supplements seem to be an effective way for individuals and doctors to prevent or treat Covid-19. Nonetheless, the outcomes of significant vitamin D randomized controlled trials are further needed." @default.
- W4376609476 created "2023-05-17" @default.
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- W4376609476 date "2022-05-01" @default.
- W4376609476 modified "2023-10-18" @default.
- W4376609476 title "Should Young Covid-19 Patients be Suplemented with Vitamin D?" @default.
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- W4376609476 doi "https://doi.org/10.2478/arsm-2022-0017" @default.
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