FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376609534> ?p ?o ?g. }

• W4376609534 abstract "Autophagy refers to the conserved cellular catabolic process relevant to lysosome activity and plays a vital role in maintaining the dynamic equilibrium of intracellular matter by degrading harmful and abnormally accumulated cellular components. Accumulating evidence has recently revealed that dysregulation of autophagy by genetic and exogenous interventions may disrupt cellular homeostasis in human diseases. In silico approaches as powerful aids to experiments have also been extensively reported to play their critical roles in the storage, prediction, and analysis of massive amounts of experimental data. Thus, modulating autophagy to treat diseases by in silico methods would be anticipated. Here, we focus on summarizing the updated in silico approaches including databases, systems biology network approaches, omics-based analyses, mathematical models, and artificial intelligence (AI) methods that sought to modulate autophagy for potential therapeutic purposes, which will provide a new insight into more promising therapeutic strategies. Autophagy-related databases are the data basis of the in silico method, storing a large amount of information about DNA, RNA, proteins, small molecules and diseases. The systems biology approach is a method to systematically study the interrelationships among biological processes including autophagy from a macroscopic perspective. Omics-based analyses are based on high-throughput data to analyze gene expression at different levels of biological processes involving autophagy. mathematical models are visualization methods to describe the dynamic process of autophagy, and its accuracy is related to the selection of parameters. AI methods use big data related to autophagy to predict autophagy targets, design targeted small molecules, and classify diverse human diseases for potential therapeutic applications." @default.
• W4376609534 created "2023-05-17" @default.
• W4376609534 creator A5022553822 @default.
• W4376609534 creator A5023713439 @default.
• W4376609534 creator A5026861620 @default.
• W4376609534 creator A5072183122 @default.
• W4376609534 date "2023-05-01" @default.
• W4376609534 modified "2023-10-05" @default.
• W4376609534 title "Modulating autophagy to treat diseases: A revisited review on in silico methods" @default.
• W4376609534 cites W1857680029 @default.
• W4376609534 cites W1935781822 @default.
• W4376609534 cites W1999998145 @default.
• W4376609534 cites W2001623365 @default.
• W4376609534 cites W2012255493 @default.
• W4376609534 cites W2025665129 @default.
• W4376609534 cites W2039609876 @default.
• W4376609534 cites W2052684956 @default.
• W4376609534 cites W2060167893 @default.
• W4376609534 cites W2066662062 @default.
• W4376609534 cites W2089578131 @default.
• W4376609534 cites W2118258530 @default.
• W4376609534 cites W2136994247 @default.
• W4376609534 cites W2154748862 @default.
• W4376609534 cites W2297562081 @default.
• W4376609534 cites W2328399538 @default.
• W4376609534 cites W2414800819 @default.
• W4376609534 cites W2549172728 @default.
• W4376609534 cites W2550771129 @default.
• W4376609534 cites W2559588208 @default.
• W4376609534 cites W2606209624 @default.
• W4376609534 cites W2612352274 @default.
• W4376609534 cites W2615994102 @default.
• W4376609534 cites W2617115371 @default.
• W4376609534 cites W2750135767 @default.
• W4376609534 cites W2753588101 @default.
• W4376609534 cites W2758797028 @default.
• W4376609534 cites W2761346730 @default.
• W4376609534 cites W2762198415 @default.
• W4376609534 cites W2766206544 @default.
• W4376609534 cites W2769700967 @default.
• W4376609534 cites W2770548163 @default.
• W4376609534 cites W2792594287 @default.
• W4376609534 cites W2795068716 @default.
• W4376609534 cites W2795845448 @default.
• W4376609534 cites W2799473901 @default.
• W4376609534 cites W2800528847 @default.
• W4376609534 cites W2807909158 @default.
• W4376609534 cites W2876917861 @default.
• W4376609534 cites W2885531813 @default.
• W4376609534 cites W2886257261 @default.
• W4376609534 cites W2887708784 @default.
• W4376609534 cites W2890280066 @default.
• W4376609534 cites W2891858794 @default.
• W4376609534 cites W2892082076 @default.
• W4376609534 cites W2898321887 @default.
• W4376609534 cites W2908201961 @default.
• W4376609534 cites W2909477364 @default.
• W4376609534 cites W2915037793 @default.
• W4376609534 cites W2919115771 @default.
• W4376609534 cites W2921882381 @default.
• W4376609534 cites W2947390945 @default.
• W4376609534 cites W2949598989 @default.
• W4376609534 cites W2950595506 @default.
• W4376609534 cites W2951482883 @default.
• W4376609534 cites W2972497960 @default.
• W4376609534 cites W2980168206 @default.
• W4376609534 cites W2980631738 @default.
• W4376609534 cites W2981184261 @default.
• W4376609534 cites W2982636185 @default.
• W4376609534 cites W2984424352 @default.
• W4376609534 cites W2997633082 @default.
• W4376609534 cites W2999704546 @default.
• W4376609534 cites W3001040093 @default.
• W4376609534 cites W3001449808 @default.
• W4376609534 cites W3001475835 @default.
• W4376609534 cites W3005857648 @default.
• W4376609534 cites W3011924010 @default.
• W4376609534 cites W3012996909 @default.
• W4376609534 cites W3013990127 @default.
• W4376609534 cites W3016390892 @default.
• W4376609534 cites W3017205475 @default.
• W4376609534 cites W3017374434 @default.
• W4376609534 cites W3020766569 @default.
• W4376609534 cites W3023042104 @default.
• W4376609534 cites W3025651178 @default.
• W4376609534 cites W3038715790 @default.
• W4376609534 cites W3041921794 @default.
• W4376609534 cites W3044505687 @default.
• W4376609534 cites W3048008447 @default.
• W4376609534 cites W3048254221 @default.
• W4376609534 cites W3048520812 @default.
• W4376609534 cites W3087381804 @default.
• W4376609534 cites W3087563071 @default.
• W4376609534 cites W3091987029 @default.
• W4376609534 cites W3092107442 @default.
• W4376609534 cites W3092966039 @default.
• W4376609534 cites W3093950086 @default.
• W4376609534 cites W3094964773 @default.
• W4376609534 cites W3097885939 @default.
• W4376609534 cites W3108118546 @default.

• next