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- W4376613908 abstract "Early treatment of COVID-19 patients could reduce hospitalization and death. The effect of corticosteroids in the outpatient setting is still unknown. This study aimed to determine the effect of corticosteroids in the prevention of hospitalization of nonsevere cases.This study is a multicenter randomized controlled trial. Seventy five nonsevere COVID-19 patients presented between days 7 and 14 of their symptoms received either prednisolone or placebo. The primary outcome was hospitalization. The study protocol was registered in the Iranian Registry of Clinical Trials on December 2, 2020 (IRCT20171219037964N2).Although the rate of hospitalization in the prednisolone group was higher than the placebo group (10.8% vs. 7.9%, respectively), it was not statistically significant (P value.,6). One patient in each group reported an adverse event and withdrew the medication.Considering the null effect of corticosteroids in the prevention of hospitalization in outpatient settings, it is suggested not to consider corticosteroids for outpatient treatment." @default.
- W4376613908 created "2023-05-17" @default.
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- W4376613908 date "2023-01-01" @default.
- W4376613908 modified "2023-10-14" @default.
- W4376613908 title "Steroid in the treatment of outpatient COVID-19: A multicenter randomized controlled trial" @default.
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- W4376613908 doi "https://doi.org/10.4103/abr.abr_72_22" @default.
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