Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376642620> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4376642620 endingPage "54" @default.
- W4376642620 startingPage "49" @default.
- W4376642620 abstract "Ivabradine, an agent lowering the heart rate, acting as a funny current (If) specific inhibitor, is responsible for the sinoatrial node's spontaneous depolarization. According to current guidelines, it is indicated in specific heart failure populations and as a second-line treatment option to improve angina in chronic coronary syndromes.The role of ivabradine in the setting of ventricular arrhythmias has been studied in both experimental and clinical studies. Specifically, experimental studies have examined the role of ivabradine in acute myocardial ischemia, reperfusion, digitalis-induced ventricular arrhythmias, and catecholaminergic polymorphic ventricular tachycardia showing promising results. In addition, clinical studies have shown a beneficial role of ivabradine in reducing ventricular arrhythmias. Ivabradine reduced premature ventricular contractions in combination with beta-blockers in dilated cardiomyopathy patients. Similarly, in catecholaminergic polymorphic ventricular tachycardia, ivabradine reduced dobutamine-induced premature ventricular complexes and improved ventricular arrhythmias burden. On the other hand, current data show no beneficial role of ivabradine in reducing ventricular arrhythmias in myocardial ischemia.Randomized clinical trials are needed to elucidate the role of ivabradine in reducing the burden of ventricular arrhythmias in various clinical settings. HIPPOKRATIA 2022, 26 (2):49-54." @default.
- W4376642620 created "2023-05-17" @default.
- W4376642620 creator A5033863295 @default.
- W4376642620 creator A5043075532 @default.
- W4376642620 creator A5059788514 @default.
- W4376642620 creator A5066697688 @default.
- W4376642620 date "2022-04-01" @default.
- W4376642620 modified "2023-09-28" @default.
- W4376642620 title "Ivabradine: pre-clinical and clinical evidence in the setting of ventricular arrhythmias." @default.
- W4376642620 cites W1567648906 @default.
- W4376642620 cites W2006816208 @default.
- W4376642620 cites W2031357491 @default.
- W4376642620 cites W2054653014 @default.
- W4376642620 cites W2071987892 @default.
- W4376642620 cites W2075866535 @default.
- W4376642620 cites W2076813032 @default.
- W4376642620 cites W2090502272 @default.
- W4376642620 cites W2136642260 @default.
- W4376642620 cites W2149791370 @default.
- W4376642620 cites W2151253049 @default.
- W4376642620 cites W2159461724 @default.
- W4376642620 cites W2163331972 @default.
- W4376642620 cites W2305214350 @default.
- W4376642620 cites W2403652391 @default.
- W4376642620 cites W2513911398 @default.
- W4376642620 cites W2593733884 @default.
- W4376642620 cites W2614670020 @default.
- W4376642620 cites W2672618914 @default.
- W4376642620 cites W2758818102 @default.
- W4376642620 cites W2777074561 @default.
- W4376642620 cites W2810145538 @default.
- W4376642620 cites W2851502571 @default.
- W4376642620 cites W2895926360 @default.
- W4376642620 cites W2944323076 @default.
- W4376642620 cites W3000383906 @default.
- W4376642620 cites W3011371150 @default.
- W4376642620 cites W3014224796 @default.
- W4376642620 cites W3086744996 @default.
- W4376642620 cites W4205728235 @default.
- W4376642620 cites W4205992414 @default.
- W4376642620 cites W4281673693 @default.
- W4376642620 cites W430462832 @default.
- W4376642620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37188047" @default.
- W4376642620 hasPublicationYear "2022" @default.
- W4376642620 type Work @default.
- W4376642620 citedByCount "0" @default.
- W4376642620 crossrefType "journal-article" @default.
- W4376642620 hasAuthorship W4376642620A5033863295 @default.
- W4376642620 hasAuthorship W4376642620A5043075532 @default.
- W4376642620 hasAuthorship W4376642620A5059788514 @default.
- W4376642620 hasAuthorship W4376642620A5066697688 @default.
- W4376642620 hasConcept C126322002 @default.
- W4376642620 hasConcept C164705383 @default.
- W4376642620 hasConcept C2776331378 @default.
- W4376642620 hasConcept C2777953023 @default.
- W4376642620 hasConcept C2778198053 @default.
- W4376642620 hasConcept C2778542873 @default.
- W4376642620 hasConcept C2779167562 @default.
- W4376642620 hasConcept C42219234 @default.
- W4376642620 hasConcept C71924100 @default.
- W4376642620 hasConcept C84393581 @default.
- W4376642620 hasConceptScore W4376642620C126322002 @default.
- W4376642620 hasConceptScore W4376642620C164705383 @default.
- W4376642620 hasConceptScore W4376642620C2776331378 @default.
- W4376642620 hasConceptScore W4376642620C2777953023 @default.
- W4376642620 hasConceptScore W4376642620C2778198053 @default.
- W4376642620 hasConceptScore W4376642620C2778542873 @default.
- W4376642620 hasConceptScore W4376642620C2779167562 @default.
- W4376642620 hasConceptScore W4376642620C42219234 @default.
- W4376642620 hasConceptScore W4376642620C71924100 @default.
- W4376642620 hasConceptScore W4376642620C84393581 @default.
- W4376642620 hasIssue "2" @default.
- W4376642620 hasLocation W43766426201 @default.
- W4376642620 hasOpenAccess W4376642620 @default.
- W4376642620 hasPrimaryLocation W43766426201 @default.
- W4376642620 hasRelatedWork W2079812387 @default.
- W4376642620 hasRelatedWork W2107838649 @default.
- W4376642620 hasRelatedWork W2131996841 @default.
- W4376642620 hasRelatedWork W2183675949 @default.
- W4376642620 hasRelatedWork W2262262884 @default.
- W4376642620 hasRelatedWork W2270377498 @default.
- W4376642620 hasRelatedWork W2610787159 @default.
- W4376642620 hasRelatedWork W2707576095 @default.
- W4376642620 hasRelatedWork W2795216625 @default.
- W4376642620 hasRelatedWork W3107858219 @default.
- W4376642620 hasVolume "26" @default.
- W4376642620 isParatext "false" @default.
- W4376642620 isRetracted "false" @default.
- W4376642620 workType "article" @default.