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- W4376648700 abstract "Peripheral arterial disease (PAD) is poorly researched compared with its cardiovascular counterparts. Existing guidelines support high intensity statin prescription in patients with PAD, with a focus on tailoring therapy to specific low density lipoprotein cholesterol (LDL-C) targets, as these directly link to clinical outcome. 1 Sucharitkul P.P.J. Jones K.L. Scott D.J.A. Bailey M.A. Lipid optimization in lower extremity peripheral arterial disease. Ann Vasc Surg. 2021; 76: 542-554 Abstract Full Text Full Text PDF Scopus (0) Google Scholar Currently, Treat to Target (T2T) and Fire and Forget (F&F) are strategies for lipid management in PAD. T2T focuses on titration of lipid lowering therapy to stringent LDL-C targets as set out by current UK National Institute for Health and Care Excellence (NICE; ≤ 1.8 mmol/L) and European Society of Cardiology (≤ 1.4 mmol/L) guidelines. 2 National Institute for Clinical Excellence2021 Recommendations Peripheral arterial disease: diagnosis and management. https://www.nice.org.uk/guidance/cg147/chapter/Recommendations#secondary-prevention-of-cardiovascular-disease-in-people-with-peripheral-arterial-diseaseDate accessed: March 14, 2023 Google Scholar ,3 Aboyans V. Ricco J.B. Bartelink M.E.L. Björck M. Brodmann M. Cohnert T. et al. 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg. 2018; 55: 305-368 Abstract Full Text Full Text PDF PubMed Scopus (574) Google Scholar F&F focuses on high intensity statin prescription without further monitoring. The performance of each approach for LDL-C reduction in patients with intermittent claudication was assessed." @default.
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- W4376648700 date "2023-09-01" @default.
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- W4376648700 title "Treat to Target Confers Enhanced Low Density Lipoprotein Cholesterol Reduction Compared With a Fire and Forget Approach in Patients With Intermittent Claudication" @default.
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- W4376648700 doi "https://doi.org/10.1016/j.ejvs.2023.05.017" @default.
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