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- W4376863396 abstract "Hepatocellular carcinoma is the major cause of death all over the world and is the fth most common cancer affecting one million individuals annually. Medicinal plants have immense potential to combat cancer without any known side effects and Selenium is an essential micronutrient that plays a vital role in maintaining good health. In this study Selenium nanoparticles of Baliospermum montanum leaf extract [SeNP] were synthesized and characterized using SEM, XRD, UV, and FTIR. Hep G2 cell lines were used to check the anticancer activity by MTT assay and Doxorubicin was used as standard. MTT assay exhibited signicantly good results with an IC50 value of 23.38 µg/ml. Two standard methods Proteinase inhibitory action and BSA denaturation assay were used to check the antiinammatory activity. The Proteinase inhibitory action exhibited an IC50 value of 698.02 µg/ml and BSA denaturation assay an IC50 value of 440.33 µg/ml. The antioxidant activity of selenium nanoparticles also showed better results by DPPH and ABTS methods. The IC50 value was found to be 72.80 µg/ml for DPPH and 65.73 µg/ml for ABTS method. Overall Selenium nanoparticles of Baliospermum montanum leaves exhibited good results for anticancer activity, anti-inammatory activity, and antioxidant activity against hepatocellular carcinoma and can be a good candidate for therapeutic and pharmaceutical use." @default.
- W4376863396 created "2023-05-18" @default.
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- W4376863396 date "2023-04-01" @default.
- W4376863396 modified "2023-09-30" @default.
- W4376863396 title "IN VITRO ANTICANCER AND ANTI-INFLAMMATORY ACTIVITY OF GREEN SYNTHESIZED SELENIUM NANOPARTICLES OF BALIOSPERMUM MONTANUM LEAF ON HEPATOCELLULAR CARCINOMA" @default.
- W4376863396 doi "https://doi.org/10.36106/ijar/9203082" @default.
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