Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376869138> ?p ?o ?g. }
- W4376869138 endingPage "154543" @default.
- W4376869138 startingPage "154543" @default.
- W4376869138 abstract "PReferentially expressed Antigen in Melanoma (PRAME) is a cancer testis antigen, first isolated in tumor-reactive T-cell clones from a metastatic melanoma patient. It has been widely studied in skin pathology as an immunohistochemical marker capable of distinguishing between benign nevi and malignant melanomas. PRAME has been found to be also expressed in non-melanocytic tumors, including lung, breast, kidney and ovarian cancer. However, less is known about the diagnostic and/or prognostic role of this protein in uveal melanoma (UM); few studies have reported that PRAME expression seems to give to UM patients an additional metastatic risk beyond the other already-known prognostic parameters. In the present retrospective study, we aimed to correlate PRAME immunoreactivity to other clinico-pathologic features and follow-up data on a large series of 85 cases (45 non-metastasizing and 40 metastasizing tumors) of primary UM. A statistically significant correlation was found between PRAME expression and higher metastatic risk and lower metastasis-free survival. We propose to include PRAME in the immunohistochemical panel of UM as an easily usable marker capable of predicting higher metastatic risk and stratifying patients' outcome." @default.
- W4376869138 created "2023-05-18" @default.
- W4376869138 creator A5027952276 @default.
- W4376869138 creator A5041028484 @default.
- W4376869138 creator A5055550598 @default.
- W4376869138 creator A5056723399 @default.
- W4376869138 creator A5057184782 @default.
- W4376869138 creator A5061495027 @default.
- W4376869138 creator A5061835885 @default.
- W4376869138 creator A5067452360 @default.
- W4376869138 creator A5074719054 @default.
- W4376869138 creator A5079099473 @default.
- W4376869138 creator A5083114518 @default.
- W4376869138 creator A5088802487 @default.
- W4376869138 creator A5088962032 @default.
- W4376869138 creator A5090000646 @default.
- W4376869138 date "2023-07-01" @default.
- W4376869138 modified "2023-10-06" @default.
- W4376869138 title "Immunohistochemical expression of PRAME is a marker of poor prognosis in uveal melanoma: A clinico-pathologic and immunohistochemical study on a series of 85 cases" @default.
- W4376869138 cites W1976244358 @default.
- W4376869138 cites W1993191461 @default.
- W4376869138 cites W2026285612 @default.
- W4376869138 cites W2300492004 @default.
- W4376869138 cites W2499451571 @default.
- W4376869138 cites W2559127842 @default.
- W4376869138 cites W2593610824 @default.
- W4376869138 cites W2608198193 @default.
- W4376869138 cites W2884769110 @default.
- W4376869138 cites W2885897872 @default.
- W4376869138 cites W2913613732 @default.
- W4376869138 cites W2935516794 @default.
- W4376869138 cites W2944683852 @default.
- W4376869138 cites W2959616452 @default.
- W4376869138 cites W3005234850 @default.
- W4376869138 cites W3008487230 @default.
- W4376869138 cites W3017281362 @default.
- W4376869138 cites W3044342719 @default.
- W4376869138 cites W3104178374 @default.
- W4376869138 cites W3159444276 @default.
- W4376869138 cites W3165388646 @default.
- W4376869138 cites W3198391937 @default.
- W4376869138 cites W3201894159 @default.
- W4376869138 cites W4200052849 @default.
- W4376869138 cites W4220961244 @default.
- W4376869138 cites W4281739369 @default.
- W4376869138 cites W4285404577 @default.
- W4376869138 cites W4292004444 @default.
- W4376869138 cites W4318203845 @default.
- W4376869138 doi "https://doi.org/10.1016/j.prp.2023.154543" @default.
- W4376869138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37210771" @default.
- W4376869138 hasPublicationYear "2023" @default.
- W4376869138 type Work @default.
- W4376869138 citedByCount "1" @default.
- W4376869138 crossrefType "journal-article" @default.
- W4376869138 hasAuthorship W4376869138A5027952276 @default.
- W4376869138 hasAuthorship W4376869138A5041028484 @default.
- W4376869138 hasAuthorship W4376869138A5055550598 @default.
- W4376869138 hasAuthorship W4376869138A5056723399 @default.
- W4376869138 hasAuthorship W4376869138A5057184782 @default.
- W4376869138 hasAuthorship W4376869138A5061495027 @default.
- W4376869138 hasAuthorship W4376869138A5061835885 @default.
- W4376869138 hasAuthorship W4376869138A5067452360 @default.
- W4376869138 hasAuthorship W4376869138A5074719054 @default.
- W4376869138 hasAuthorship W4376869138A5079099473 @default.
- W4376869138 hasAuthorship W4376869138A5083114518 @default.
- W4376869138 hasAuthorship W4376869138A5088802487 @default.
- W4376869138 hasAuthorship W4376869138A5088962032 @default.
- W4376869138 hasAuthorship W4376869138A5090000646 @default.
- W4376869138 hasBestOaLocation W43768691381 @default.
- W4376869138 hasConcept C121608353 @default.
- W4376869138 hasConcept C126322002 @default.
- W4376869138 hasConcept C142724271 @default.
- W4376869138 hasConcept C143998085 @default.
- W4376869138 hasConcept C204232928 @default.
- W4376869138 hasConcept C2777658100 @default.
- W4376869138 hasConcept C2779013556 @default.
- W4376869138 hasConcept C502942594 @default.
- W4376869138 hasConcept C71924100 @default.
- W4376869138 hasConceptScore W4376869138C121608353 @default.
- W4376869138 hasConceptScore W4376869138C126322002 @default.
- W4376869138 hasConceptScore W4376869138C142724271 @default.
- W4376869138 hasConceptScore W4376869138C143998085 @default.
- W4376869138 hasConceptScore W4376869138C204232928 @default.
- W4376869138 hasConceptScore W4376869138C2777658100 @default.
- W4376869138 hasConceptScore W4376869138C2779013556 @default.
- W4376869138 hasConceptScore W4376869138C502942594 @default.
- W4376869138 hasConceptScore W4376869138C71924100 @default.
- W4376869138 hasLocation W43768691381 @default.
- W4376869138 hasLocation W43768691382 @default.
- W4376869138 hasOpenAccess W4376869138 @default.
- W4376869138 hasPrimaryLocation W43768691381 @default.
- W4376869138 hasRelatedWork W1588533041 @default.
- W4376869138 hasRelatedWork W2021968456 @default.
- W4376869138 hasRelatedWork W2068861579 @default.
- W4376869138 hasRelatedWork W2159897971 @default.
- W4376869138 hasRelatedWork W2353600181 @default.
- W4376869138 hasRelatedWork W2371735115 @default.
- W4376869138 hasRelatedWork W2393830862 @default.