Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376873048> ?p ?o ?g. }
- W4376873048 abstract "Abstract Heterocycles with nitrogen‐nitrogen (N−N) bonds are privileged building blocks of synthetic drugs. They are also found in natural products, although the biosynthetic logic behind them is poorly understood. Actinopyridazinones produced by Streptomyces sp. MSD090630SC‐05 possess unique dihydropyridazinone rings that have been studied as core nuclei in several approved synthetic therapeutics. Herein, we performed gene knockouts and in vitro biochemical experiments to elucidate the major steps in actinopyridazinone biosynthesis, including the unprecedented carrier protein mediated machinery for dihydropyridazinone formation." @default.
- W4376873048 created "2023-05-18" @default.
- W4376873048 creator A5044491238 @default.
- W4376873048 creator A5055131198 @default.
- W4376873048 creator A5064472249 @default.
- W4376873048 creator A5089507010 @default.
- W4376873048 creator A5091046338 @default.
- W4376873048 date "2023-06-06" @default.
- W4376873048 modified "2023-10-17" @default.
- W4376873048 title "Carrier Protein Mediated Formation of the Dihydropyridazinone Ring in Actinopyridazinone Biosynthesis" @default.
- W4376873048 cites W1985424949 @default.
- W4376873048 cites W2030035423 @default.
- W4376873048 cites W2071280170 @default.
- W4376873048 cites W2076165765 @default.
- W4376873048 cites W2094919403 @default.
- W4376873048 cites W2346652445 @default.
- W4376873048 cites W2506627165 @default.
- W4376873048 cites W2556720820 @default.
- W4376873048 cites W2604872822 @default.
- W4376873048 cites W2695325110 @default.
- W4376873048 cites W2824379583 @default.
- W4376873048 cites W2911530530 @default.
- W4376873048 cites W2928699041 @default.
- W4376873048 cites W2953150921 @default.
- W4376873048 cites W2954167186 @default.
- W4376873048 cites W2971696868 @default.
- W4376873048 cites W2973113340 @default.
- W4376873048 cites W3014624155 @default.
- W4376873048 cites W3025841913 @default.
- W4376873048 cites W3044294667 @default.
- W4376873048 cites W3093591145 @default.
- W4376873048 cites W3096002958 @default.
- W4376873048 cites W3126291512 @default.
- W4376873048 cites W3137627626 @default.
- W4376873048 cites W3209680340 @default.
- W4376873048 cites W4200190904 @default.
- W4376873048 cites W4206161772 @default.
- W4376873048 cites W4220807920 @default.
- W4376873048 cites W4221011896 @default.
- W4376873048 cites W4283731961 @default.
- W4376873048 cites W4293213018 @default.
- W4376873048 cites W4366351965 @default.
- W4376873048 cites W914528071 @default.
- W4376873048 doi "https://doi.org/10.1002/anie.202305155" @default.
- W4376873048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37194491" @default.
- W4376873048 hasPublicationYear "2023" @default.
- W4376873048 type Work @default.
- W4376873048 citedByCount "0" @default.
- W4376873048 crossrefType "journal-article" @default.
- W4376873048 hasAuthorship W4376873048A5044491238 @default.
- W4376873048 hasAuthorship W4376873048A5055131198 @default.
- W4376873048 hasAuthorship W4376873048A5064472249 @default.
- W4376873048 hasAuthorship W4376873048A5089507010 @default.
- W4376873048 hasAuthorship W4376873048A5091046338 @default.
- W4376873048 hasConcept C104317684 @default.
- W4376873048 hasConcept C178790620 @default.
- W4376873048 hasConcept C185592680 @default.
- W4376873048 hasConcept C191908910 @default.
- W4376873048 hasConcept C202751555 @default.
- W4376873048 hasConcept C21951064 @default.
- W4376873048 hasConcept C2779920670 @default.
- W4376873048 hasConcept C2780378348 @default.
- W4376873048 hasConcept C3675279 @default.
- W4376873048 hasConcept C523546767 @default.
- W4376873048 hasConcept C54355233 @default.
- W4376873048 hasConcept C553450214 @default.
- W4376873048 hasConcept C55493867 @default.
- W4376873048 hasConcept C70721500 @default.
- W4376873048 hasConcept C86803240 @default.
- W4376873048 hasConceptScore W4376873048C104317684 @default.
- W4376873048 hasConceptScore W4376873048C178790620 @default.
- W4376873048 hasConceptScore W4376873048C185592680 @default.
- W4376873048 hasConceptScore W4376873048C191908910 @default.
- W4376873048 hasConceptScore W4376873048C202751555 @default.
- W4376873048 hasConceptScore W4376873048C21951064 @default.
- W4376873048 hasConceptScore W4376873048C2779920670 @default.
- W4376873048 hasConceptScore W4376873048C2780378348 @default.
- W4376873048 hasConceptScore W4376873048C3675279 @default.
- W4376873048 hasConceptScore W4376873048C523546767 @default.
- W4376873048 hasConceptScore W4376873048C54355233 @default.
- W4376873048 hasConceptScore W4376873048C553450214 @default.
- W4376873048 hasConceptScore W4376873048C55493867 @default.
- W4376873048 hasConceptScore W4376873048C70721500 @default.
- W4376873048 hasConceptScore W4376873048C86803240 @default.
- W4376873048 hasFunder F4320309785 @default.
- W4376873048 hasFunder F4320309996 @default.
- W4376873048 hasFunder F4320310657 @default.
- W4376873048 hasFunder F4320310760 @default.
- W4376873048 hasFunder F4320311405 @default.
- W4376873048 hasFunder F4320333596 @default.
- W4376873048 hasFunder F4320334764 @default.
- W4376873048 hasFunder F4320338246 @default.
- W4376873048 hasIssue "29" @default.
- W4376873048 hasLocation W43768730481 @default.
- W4376873048 hasLocation W43768730482 @default.
- W4376873048 hasOpenAccess W4376873048 @default.
- W4376873048 hasPrimaryLocation W43768730481 @default.
- W4376873048 hasRelatedWork W2009687716 @default.
- W4376873048 hasRelatedWork W2072526354 @default.
- W4376873048 hasRelatedWork W2099102792 @default.