FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376875310> ?p ?o ?g. }

• W4376875310 endingPage "8851" @default.
• W4376875310 startingPage "8851" @default.
• W4376875310 abstract "Sepsis is a common disease in sub-Saharan Africa and Asia, where malaria is also prevalent. To determine whether Plasmodium infection might enhance susceptibility to endotoxin shock, we used a mouse model of lipopolysaccharide (LPS) administration. Our results indicated that Plasmodium yoelii infection in mice strongly enhanced the susceptibility of the host to develop endotoxin shock. This increased susceptibility to endotoxin shock was correlated with a synergistic effect of Plasmodium and LPS on the secretion of Tumor Necrosis Factor (TNF). TNF contributed mostly to lethality after the dual challenge since neutralization with an anti-TNF antibody provided protection from death. Plasmodium infection also induced an enhancement of the serum levels of LPS soluble ligands, sCD14 and Lipopolysaccharide Binding Protein. In this regard, our data confirm that Plasmodium infection can profoundly modify responses to secondary bacteria challenges, resulting in dysregulated cytokine expression and pathological effects. If confirmed in humans, LPS soluble receptors might serve as markers of susceptibility to septic shock." @default.
• W4376875310 created "2023-05-18" @default.
• W4376875310 creator A5039082432 @default.
• W4376875310 creator A5066478747 @default.
• W4376875310 date "2023-05-16" @default.
• W4376875310 modified "2023-10-14" @default.
• W4376875310 title "Enhanced Mouse Susceptibility to Endotoxin Shock after Plasmodium yoelii Infection Is Correlated with Increased Serum Levels of Lipopolysaccharide Soluble Receptors" @default.
• W4376875310 cites W1531345276 @default.
• W4376875310 cites W1591835130 @default.
• W4376875310 cites W1600316709 @default.
• W4376875310 cites W1648631879 @default.
• W4376875310 cites W1671369824 @default.
• W4376875310 cites W1841886004 @default.
• W4376875310 cites W1964465730 @default.
• W4376875310 cites W1967628584 @default.
• W4376875310 cites W1968241763 @default.
• W4376875310 cites W1969315310 @default.
• W4376875310 cites W1982479634 @default.
• W4376875310 cites W1991773233 @default.
• W4376875310 cites W2029157767 @default.
• W4376875310 cites W2048559240 @default.
• W4376875310 cites W2064626913 @default.
• W4376875310 cites W2091961926 @default.
• W4376875310 cites W2095833996 @default.
• W4376875310 cites W2103035923 @default.
• W4376875310 cites W2113828544 @default.
• W4376875310 cites W2120699270 @default.
• W4376875310 cites W2122709899 @default.
• W4376875310 cites W2125844015 @default.
• W4376875310 cites W2144589352 @default.
• W4376875310 cites W2149466293 @default.
• W4376875310 cites W2152659473 @default.
• W4376875310 cites W2162511967 @default.
• W4376875310 cites W2165467811 @default.
• W4376875310 cites W2190014693 @default.
• W4376875310 cites W2207634473 @default.
• W4376875310 cites W2317184793 @default.
• W4376875310 cites W2724317418 @default.
• W4376875310 cites W2998853022 @default.
• W4376875310 cites W3014159486 @default.
• W4376875310 cites W3149352469 @default.
• W4376875310 cites W4294921172 @default.
• W4376875310 cites W4313347806 @default.
• W4376875310 doi "https://doi.org/10.3390/ijms24108851" @default.
• W4376875310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37240201" @default.
• W4376875310 hasPublicationYear "2023" @default.
• W4376875310 type Work @default.
• W4376875310 citedByCount "0" @default.
• W4376875310 crossrefType "journal-article" @default.
• W4376875310 hasAuthorship W4376875310A5039082432 @default.
• W4376875310 hasAuthorship W4376875310A5066478747 @default.
• W4376875310 hasBestOaLocation W43768753101 @default.
• W4376875310 hasConcept C104317684 @default.
• W4376875310 hasConcept C126322002 @default.
• W4376875310 hasConcept C136764020 @default.
• W4376875310 hasConcept C170493617 @default.
• W4376875310 hasConcept C17991360 @default.
• W4376875310 hasConcept C203014093 @default.
• W4376875310 hasConcept C205260736 @default.
• W4376875310 hasConcept C2775867548 @default.
• W4376875310 hasConcept C2776486806 @default.
• W4376875310 hasConcept C2777628635 @default.
• W4376875310 hasConcept C2778048844 @default.
• W4376875310 hasConcept C2778371730 @default.
• W4376875310 hasConcept C2778384902 @default.
• W4376875310 hasConcept C2778675580 @default.
• W4376875310 hasConcept C2778690821 @default.
• W4376875310 hasConcept C2778754761 @default.
• W4376875310 hasConcept C2779341262 @default.
• W4376875310 hasConcept C2781300812 @default.
• W4376875310 hasConcept C41008148 @default.
• W4376875310 hasConcept C55493867 @default.
• W4376875310 hasConcept C71924100 @default.
• W4376875310 hasConcept C71928629 @default.
• W4376875310 hasConcept C86803240 @default.
• W4376875310 hasConcept C8891405 @default.
• W4376875310 hasConcept C89423630 @default.
• W4376875310 hasConceptScore W4376875310C104317684 @default.
• W4376875310 hasConceptScore W4376875310C126322002 @default.
• W4376875310 hasConceptScore W4376875310C136764020 @default.
• W4376875310 hasConceptScore W4376875310C170493617 @default.
• W4376875310 hasConceptScore W4376875310C17991360 @default.
• W4376875310 hasConceptScore W4376875310C203014093 @default.
• W4376875310 hasConceptScore W4376875310C205260736 @default.
• W4376875310 hasConceptScore W4376875310C2775867548 @default.
• W4376875310 hasConceptScore W4376875310C2776486806 @default.
• W4376875310 hasConceptScore W4376875310C2777628635 @default.
• W4376875310 hasConceptScore W4376875310C2778048844 @default.
• W4376875310 hasConceptScore W4376875310C2778371730 @default.
• W4376875310 hasConceptScore W4376875310C2778384902 @default.
• W4376875310 hasConceptScore W4376875310C2778675580 @default.
• W4376875310 hasConceptScore W4376875310C2778690821 @default.
• W4376875310 hasConceptScore W4376875310C2778754761 @default.
• W4376875310 hasConceptScore W4376875310C2779341262 @default.
• W4376875310 hasConceptScore W4376875310C2781300812 @default.
• W4376875310 hasConceptScore W4376875310C41008148 @default.
• W4376875310 hasConceptScore W4376875310C55493867 @default.
• W4376875310 hasConceptScore W4376875310C71924100 @default.

• next