FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4376875443> ?p ?o ?g. }

• W4376875443 endingPage "8850" @default.
• W4376875443 startingPage "8850" @default.
• W4376875443 abstract "Globally, over the next few decades, more than 2.5 billion people will suffer from hearing impairment, including profound hearing loss, and millions could potentially benefit from a cochlea implant. To date, several studies have focused on tissue trauma caused by cochlea implantation. The direct immune reaction in the inner ear after an implantation has not been well studied. Recently, therapeutic hypothermia has been found to positively influence the inflammatory reaction caused by electrode insertion trauma. The present study aimed to evaluate the hypothermic effect on the structure, numbers, function and reactivity of macrophages and microglial cells. Therefore, the distribution and activated forms of macrophages in the cochlea were evaluated in an electrode insertion trauma cochlea culture model in normothermic and mild hypothermic conditions. In 10-day-old mouse cochleae, artificial electrode insertion trauma was inflicted, and then they were cultured for 24 h at 37 °C and 32 °C. The influence of mild hypothermia on macrophages was evaluated using immunostaining of cryosections using antibodies against IBA1, F4/80, CD45 and CD163. A clear influence of mild hypothermia on the distribution of activated and non-activated forms of macrophages and monocytes in the inner ear was observed. Furthermore, these cells were located in the mesenchymal tissue in and around the cochlea, and the activated forms were found in and around the spiral ganglion tissue at 37 °C. Our findings suggest that mild hypothermic treatment has a beneficial effect on immune system activation after electrode insertion trauma." @default.
• W4376875443 created "2023-05-18" @default.
• W4376875443 creator A5014113177 @default.
• W4376875443 creator A5036158187 @default.
• W4376875443 creator A5039173642 @default.
• W4376875443 creator A5076994076 @default.
• W4376875443 creator A5077811485 @default.
• W4376875443 creator A5080318235 @default.
• W4376875443 date "2023-05-16" @default.
• W4376875443 modified "2023-09-27" @default.
• W4376875443 title "Effects of Therapeutic Hypothermia on Macrophages in Mouse Cochlea Explants" @default.
• W4376875443 cites W1523259102 @default.
• W4376875443 cites W1798123424 @default.
• W4376875443 cites W1804349295 @default.
• W4376875443 cites W1870017858 @default.
• W4376875443 cites W1960832851 @default.
• W4376875443 cites W1965561337 @default.
• W4376875443 cites W1968081526 @default.
• W4376875443 cites W1973406593 @default.
• W4376875443 cites W1984184977 @default.
• W4376875443 cites W1988201931 @default.
• W4376875443 cites W1990115192 @default.
• W4376875443 cites W1994945510 @default.
• W4376875443 cites W1995894734 @default.
• W4376875443 cites W2005154068 @default.
• W4376875443 cites W2008450997 @default.
• W4376875443 cites W2008588817 @default.
• W4376875443 cites W2018286119 @default.
• W4376875443 cites W2025490993 @default.
• W4376875443 cites W2027125450 @default.
• W4376875443 cites W2047729161 @default.
• W4376875443 cites W2051245045 @default.
• W4376875443 cites W2058229310 @default.
• W4376875443 cites W2060766291 @default.
• W4376875443 cites W2061518229 @default.
• W4376875443 cites W2067368569 @default.
• W4376875443 cites W2078619125 @default.
• W4376875443 cites W2090772730 @default.
• W4376875443 cites W2097645887 @default.
• W4376875443 cites W2112516157 @default.
• W4376875443 cites W2129861885 @default.
• W4376875443 cites W2152624886 @default.
• W4376875443 cites W2152887115 @default.
• W4376875443 cites W2178083527 @default.
• W4376875443 cites W2209180556 @default.
• W4376875443 cites W2268631802 @default.
• W4376875443 cites W2419527353 @default.
• W4376875443 cites W2552740926 @default.
• W4376875443 cites W2598519737 @default.
• W4376875443 cites W2765904780 @default.
• W4376875443 cites W2768627185 @default.
• W4376875443 cites W2790893948 @default.
• W4376875443 cites W2792120462 @default.
• W4376875443 cites W2799465684 @default.
• W4376875443 cites W2911380898 @default.
• W4376875443 cites W2949246003 @default.
• W4376875443 cites W2963421937 @default.
• W4376875443 cites W3016279791 @default.
• W4376875443 cites W3025547101 @default.
• W4376875443 cites W3026606390 @default.
• W4376875443 cites W3120995574 @default.
• W4376875443 cites W3169704303 @default.
• W4376875443 cites W3202391256 @default.
• W4376875443 cites W3216580791 @default.
• W4376875443 cites W4295138665 @default.
• W4376875443 cites W4312084347 @default.
• W4376875443 cites W4365455519 @default.
• W4376875443 cites W50233419 @default.
• W4376875443 doi "https://doi.org/10.3390/ijms24108850" @default.
• W4376875443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37240196" @default.
• W4376875443 hasPublicationYear "2023" @default.
• W4376875443 type Work @default.
• W4376875443 citedByCount "0" @default.
• W4376875443 crossrefType "journal-article" @default.
• W4376875443 hasAuthorship W4376875443A5014113177 @default.
• W4376875443 hasAuthorship W4376875443A5036158187 @default.
• W4376875443 hasAuthorship W4376875443A5039173642 @default.
• W4376875443 hasAuthorship W4376875443A5076994076 @default.
• W4376875443 hasAuthorship W4376875443A5077811485 @default.
• W4376875443 hasAuthorship W4376875443A5080318235 @default.
• W4376875443 hasBestOaLocation W43768754431 @default.
• W4376875443 hasConcept C105702510 @default.
• W4376875443 hasConcept C142724271 @default.
• W4376875443 hasConcept C16685009 @default.
• W4376875443 hasConcept C185592680 @default.
• W4376875443 hasConcept C203014093 @default.
• W4376875443 hasConcept C204232928 @default.
• W4376875443 hasConcept C2777390192 @default.
• W4376875443 hasConcept C2778500370 @default.
• W4376875443 hasConcept C2779152698 @default.
• W4376875443 hasConcept C2780130748 @default.
• W4376875443 hasConcept C42219234 @default.
• W4376875443 hasConcept C4224716 @default.
• W4376875443 hasConcept C71924100 @default.
• W4376875443 hasConcept C8891405 @default.
• W4376875443 hasConceptScore W4376875443C105702510 @default.
• W4376875443 hasConceptScore W4376875443C142724271 @default.
• W4376875443 hasConceptScore W4376875443C16685009 @default.

• next