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- W4376880149 abstract "Our cover features immunofluorescence stainings of human keratinocytes using GPCR19 (shown in red) and P2X7R (shown in green) antibodies. This image is from the article by Ghaderpour et al. in which the authors investigate the effect of the GPCR19 agonist, TDCA, on atopic dermatitis using human keratinocytes. The authors demonstrate that GPCR19 and P2X7R are colocalized on the keratinocyte membrane and that TDCA can ameliorate atopic inflammation by regulating the GPCR19-P2X7R-NLRP3 inflammasome pathway. These findings provide novel insights into potential therapeutic approaches for attenuating the pro-inflammatory features of AD patients." @default.
- W4376880149 created "2023-05-18" @default.
- W4376880149 date "2023-05-01" @default.
- W4376880149 modified "2023-09-29" @default.
- W4376880149 doi "https://doi.org/10.1002/eji.v53.5" @default.
- W4376880149 hasPublicationYear "2023" @default.
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