FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377010380> ?p ?o ?g. }

• W4377010380 endingPage "3182" @default.
• W4377010380 startingPage "3177" @default.
• W4377010380 abstract "The link between human leukocyte antigen (HLA) alleles and carbamazepine-induced cutaneous, respiratory, and gastrointestinal adverse drug reactions (ADR) has created a window of opportunity for preventing certain forms of cutaneous adverse drug reactions (cADRs); however, there is not enough data to make pharmacogenomic recommendations that can be implemented globally. The aim of this study is to assess and document carbamazepine-induced adverse reactions among prescribed Saudi/non-Saudi patients. A retrospective chart review was performed for patients who received carbamazepine (CBZ) in the period between 2016 and 2020, in the Kingdom of Saudi Arabia. Data were gathered and descriptive statistical analyses were performed on the data for the study sample. Comparisons were made using the chi-square test or independent samples' t-test. Statistical significance was considered at p < .05. All statistical analyses were performed using IBM SPSS 21.0 (Armonk, NY; IBM Corp). Results from multivariate logistic regression analyses showed that higher likelihood of carbamazepine-induced adverse reactions was significantly associated with younger age, OR = 0.82, 95% CI (0.74, 0.90); p < 0.001. Patients who were prescribed CBZ for reasons other than epilepsy or seizures were significantly more likely to develop carbamazepine-induced adverse reactions (epilepsy vs. other; OR = 0.63, p = 0.013; seizures vs. other; OR = 0.59, p = 0.018). Gender or medication duration were not related to carbamazepine-induced adverse reactions (p > 0.05). The findings of this study are comparable with those of other studies assessing carbamazepine-associated adverse reactions in children and adults. Recommendations include genetic prescreening, educating patients and parents on the possibility of adverse reactions, and routine laboratory monitoring." @default.
• W4377010380 created "2023-05-19" @default.
• W4377010380 creator A5000070555 @default.
• W4377010380 creator A5009618407 @default.
• W4377010380 creator A5015813047 @default.
• W4377010380 creator A5021850188 @default.
• W4377010380 creator A5059896819 @default.
• W4377010380 creator A5067278004 @default.
• W4377010380 date "2023-05-18" @default.
• W4377010380 modified "2023-10-15" @default.
• W4377010380 title "A highlight on carbamazepine-induced adverse drug reactions in Saudi Arabia: a retrospective medical records-based study" @default.
• W4377010380 cites W1142857625 @default.
• W4377010380 cites W1971629227 @default.
• W4377010380 cites W1983783995 @default.
• W4377010380 cites W1990791135 @default.
• W4377010380 cites W1995447433 @default.
• W4377010380 cites W2014794958 @default.
• W4377010380 cites W2047064722 @default.
• W4377010380 cites W2051828712 @default.
• W4377010380 cites W2057802344 @default.
• W4377010380 cites W2072376495 @default.
• W4377010380 cites W2077021518 @default.
• W4377010380 cites W2090094984 @default.
• W4377010380 cites W2094975151 @default.
• W4377010380 cites W2111508045 @default.
• W4377010380 cites W2112255088 @default.
• W4377010380 cites W2120103968 @default.
• W4377010380 cites W2136143199 @default.
• W4377010380 cites W2140273121 @default.
• W4377010380 cites W2164893689 @default.
• W4377010380 cites W2171583595 @default.
• W4377010380 cites W2343930718 @default.
• W4377010380 cites W2442955058 @default.
• W4377010380 cites W2599150585 @default.
• W4377010380 cites W2769985603 @default.
• W4377010380 cites W2774631894 @default.
• W4377010380 cites W2808602373 @default.
• W4377010380 cites W2903060406 @default.
• W4377010380 cites W2923212435 @default.
• W4377010380 cites W4243689842 @default.
• W4377010380 cites W86972048 @default.
• W4377010380 doi "https://doi.org/10.1007/s00210-023-02525-2" @default.
• W4377010380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37199768" @default.
• W4377010380 hasPublicationYear "2023" @default.
• W4377010380 type Work @default.
• W4377010380 citedByCount "0" @default.
• W4377010380 crossrefType "journal-article" @default.
• W4377010380 hasAuthorship W4377010380A5000070555 @default.
• W4377010380 hasAuthorship W4377010380A5009618407 @default.
• W4377010380 hasAuthorship W4377010380A5015813047 @default.
• W4377010380 hasAuthorship W4377010380A5021850188 @default.
• W4377010380 hasAuthorship W4377010380A5059896819 @default.
• W4377010380 hasAuthorship W4377010380A5067278004 @default.
• W4377010380 hasBestOaLocation W43770103801 @default.
• W4377010380 hasConcept C118552586 @default.
• W4377010380 hasConcept C126322002 @default.
• W4377010380 hasConcept C151956035 @default.
• W4377010380 hasConcept C167135981 @default.
• W4377010380 hasConcept C197934379 @default.
• W4377010380 hasConcept C2778186239 @default.
• W4377010380 hasConcept C2779253243 @default.
• W4377010380 hasConcept C2780035454 @default.
• W4377010380 hasConcept C2780542314 @default.
• W4377010380 hasConcept C65409693 @default.
• W4377010380 hasConcept C71924100 @default.
• W4377010380 hasConcept C98274493 @default.
• W4377010380 hasConceptScore W4377010380C118552586 @default.
• W4377010380 hasConceptScore W4377010380C126322002 @default.
• W4377010380 hasConceptScore W4377010380C151956035 @default.
• W4377010380 hasConceptScore W4377010380C167135981 @default.
• W4377010380 hasConceptScore W4377010380C197934379 @default.
• W4377010380 hasConceptScore W4377010380C2778186239 @default.
• W4377010380 hasConceptScore W4377010380C2779253243 @default.
• W4377010380 hasConceptScore W4377010380C2780035454 @default.
• W4377010380 hasConceptScore W4377010380C2780542314 @default.
• W4377010380 hasConceptScore W4377010380C65409693 @default.
• W4377010380 hasConceptScore W4377010380C71924100 @default.
• W4377010380 hasConceptScore W4377010380C98274493 @default.
• W4377010380 hasIssue "11" @default.
• W4377010380 hasLocation W43770103801 @default.
• W4377010380 hasLocation W43770103802 @default.
• W4377010380 hasOpenAccess W4377010380 @default.
• W4377010380 hasPrimaryLocation W43770103801 @default.
• W4377010380 hasRelatedWork W1985937992 @default.
• W4377010380 hasRelatedWork W2019020053 @default.
• W4377010380 hasRelatedWork W2054180912 @default.
• W4377010380 hasRelatedWork W2057573263 @default.
• W4377010380 hasRelatedWork W2089362184 @default.
• W4377010380 hasRelatedWork W2390115927 @default.
• W4377010380 hasRelatedWork W2398881293 @default.
• W4377010380 hasRelatedWork W2460864373 @default.
• W4377010380 hasRelatedWork W2485927482 @default.
• W4377010380 hasRelatedWork W2185975764 @default.
• W4377010380 hasVolume "396" @default.
• W4377010380 isParatext "false" @default.
• W4377010380 isRetracted "false" @default.
• W4377010380 workType "article" @default.