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- W4377010767 abstract "Mantle cell lymphoma is considered an aggressive B-cell lymphoma. The optimal induction regimen remains controversial as no randomized controlled trial has compared the efficacy of different induction therapies.Herein, we performed a retrospective analysis of the clinical characteristics of 10 patients who received induction treatment consisting of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) and rituximab, bendamustine, and cytarabine (R-BAC) at Toranomon Hospital between November 2016 and February 2022.Although one patient discontinued R-BAC therapy due to a rash, the other nine completed the scheduled chemotherapy. All patients achieved complete response, underwent high-dose chemotherapy and autologous stem cell transplantation, and maintained complete remission with a median follow-up of 15 months. Hematological adverse events (AEs) occurred in all patients; however, none developed documented infection. There were also no fatal non-hematological AEs specific to R-BAC.R-CHOP/R-BAC may be a good induction therapy for transplant-eligible patients with mantle cell lymphoma." @default.
- W4377010767 created "2023-05-19" @default.
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- W4377010767 date "2023-05-18" @default.
- W4377010767 modified "2023-10-01" @default.
- W4377010767 title "Rituximab/bendamustine/cytarabine for transplant‐eligible patients with mantle cell lymphoma: A retrospective study" @default.
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- W4377010767 doi "https://doi.org/10.1002/cam4.6114" @default.
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